Condition: Situs inversus totalis
rs138890576
in
DNAH5
gene and
Situs inversus totalis
PMID 26938784
2016 A prospective evaluation of whole-exome sequencing as a first-tier molecular test in infants with suspected monogenic disorders.
rs528302390
in
PKD1L1
gene and
Situs inversus totalis
PMID 27616478
2016 Bi-allelic Mutations in PKD1L1 Are Associated with Laterality Defects in Humans.
PMID 27616478
2016 In the second family, a homozygous
c.5072G>C
(
p.Cys1691Ser
) missense mutation was detected in an individual with
SIT
and congenital heart disease.