Condition: Syndactyly Cenani Lenz type


rs267607220 in LRP4 gene and Syndactyly Cenani Lenz type PMID 20381006 2010 LRP4 mutations alter Wnt/beta-catenin signaling and cause limb and kidney malformations in Cenani-Lenz syndrome.

PMID 28559208 2017 Novel splice mutation in LRP4 causes severe type of Cenani-Lenz syndactyly syndrome with oro-facial and skeletal symptoms.