Gene: ACMSD

Alternate names for this Gene: -

Gene Summary: The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004].

Gene is located in Chromosome: 2

Location in Chromosome : 2q21.3

Description of this Gene: aminocarboxymuconate semialdehyde decarboxylase

Type of Gene: protein-coding

Gene: CCNT2-AS1

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

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rs10198552 in ACMSD;CCNT2-AS1 gene and Aspartate aminotransferase measurement PMID 23251661 2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

rs6430549 in ACMSD;CCNT2-AS1 gene and Hematocrit procedure PMID 28017375 2017 Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.

rs10198552 in ACMSD;CCNT2-AS1 gene and Polysomnography PMID 23251661 2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.