Condition: Aspartate aminotransferase measurement
rs137866734
in
ABCA4
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs2241339
in
ABCB11
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs17342773
in
ABTB2
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs10198552
in
ACMSD;CCNT2-AS1
gene and
Aspartate aminotransferase measurement
PMID 23251661
2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
rs76622665
in
ADAMTS6
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs319991
in
AGBL4
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs7043196
in
AKNA
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs671
in
ALDH2
gene and
Aspartate aminotransferase measurement
PMID 30718733
2019 Moreover, 9 missense variants were newly identified, of which we identified new associations between a common population-specific missense variant,
rs671
(
p.Glu457Lys
) of ALDH2, and two traits including
aspartate aminotransferase
(P = 5.20 × 10<sup>-13</sup>) and alanine aminotransferase (P = 4.98 × 10<sup>-8</sup>).
rs686288
in
ANO4
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs7865362
in
B4GALT1
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs182700961
in
C2orf16
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs7825271
in
C8orf34
gene and
Aspartate aminotransferase measurement
PMID 23251661
2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
rs2489201
in
CACNB2
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs139761834
in
CD36
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs596406
in
CELF2
gene and
Aspartate aminotransferase measurement
PMID 24124411
2013 Genome-wide association study of liver enzymes in korean children.
rs892295
in
CHL1
gene and
Aspartate aminotransferase measurement
PMID 23251661
2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
rs10509735
in
CNNM1
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs333947
in
CSF1
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs79105258
in
CUX2
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs1818782
in
DAB2;C9
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs10165093
in
EFHD1
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs34010237
in
FCGRT
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs76850691
in
GOT1
gene and
Aspartate aminotransferase measurement
PMID 24124411
2013 Genome-wide association study of liver enzymes in korean children.
PMID 30718733
2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.
rs73550818
in
GOT2
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs9389268
in
HBS1L
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs11066280
in
HECTD4
gene and
Aspartate aminotransferase measurement
PMID 30718733
2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.
rs72838936
in
HPSE2
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs147627531
in
KCNIP4
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs6455128
in
KHDRBS2
gene and
Aspartate aminotransferase measurement
PMID 18464913
2008 A genome-wide association study identifies protein quantitative trait loci (pQTLs).
rs862946
in
LINC02306
gene and
Aspartate aminotransferase measurement
PMID 24124411
2013 Genome-wide association study of liver enzymes in korean children.
rs77213573
in
LINC02608
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs73154660
in
LOC101928236
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs17109512
in
LOC105378449
gene and
Aspartate aminotransferase measurement
PMID 21900944
2011 We carried out a genome-wide association study of serum
aspartate aminotransferase
(
AST
) activity in 866 Amish participants of the Heredity and Phenotype Intervention Heart Study and identified significant association of
AST
activity with a cluster of single nucleotide polymorphisms located on chromosome 10q24.1 (peak association was
rs17109512
; P=2.80E-14), in the vicinity of GOT1, the gene encoding cytosolic AST (cAST).
rs2477664
in
MRC1
gene and
Aspartate aminotransferase measurement
PMID 20139978
2010 Genome-wide association study of hematological and biochemical traits in a Japanese population.
rs2078087
in
NMNAT2
gene and
Aspartate aminotransferase measurement
PMID 23251661
2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
rs115695709
in
NOTCH4
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs11820744
in
OSBPL5;LOC107987158
gene and
Aspartate aminotransferase measurement
PMID 31311600
2019 GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network.
rs74913549
in
PANX1
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs118107800
in
PDCD4-AS1;PDCD4
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs17835714
in
PDE7B
gene and
Aspartate aminotransferase measurement
PMID 31219225
2019 Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium.
rs2896019
in
PNPLA3
gene and
Aspartate aminotransferase measurement
PMID 20139978
2010 Genome-wide association study of hematological and biochemical traits in a Japanese population.
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
PMID 31219225
2019 In the PNPLA3 gene,
rs4823173
(P = 3.44 × 10<sup>-10</sup> ), rs2896019 (P = 7.29 × 10<sup>-9</sup> ), and rs2281135 (P = 8.73 × 10<sup>-9</sup> ) were significantly associated with
AST
levels.
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs11292716
in
PON1
gene and
Aspartate aminotransferase measurement
PMID 28240269
2017 Connecting genetic risk to disease end points through the human blood plasma proteome.
rs34173
in
PPP1R17;PDE1C
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs191610380
in
PPP2R2A
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs139271658
in
PTPRD
gene and
Aspartate aminotransferase measurement
PMID 31311600
2019 GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network.
rs117983281
in
PUM3
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs13077101
in
RABL3
gene and
Aspartate aminotransferase measurement
PMID 23251661
2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
rs2371605
in
RBMS3
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs2491441
in
RGL1
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs76053346
in
SHOC2
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs12803802
in
SLC35F2
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs10272006
in
SP4
gene and
Aspartate aminotransferase measurement
PMID 31311600
2019 GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network.
rs4949718
in
ST6GALNAC3
gene and
Aspartate aminotransferase measurement
PMID 24124411
2013 Genome-wide association study of liver enzymes in korean children.
rs144430312
in
STAM
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs6855088
in
TENM3
gene and
Aspartate aminotransferase measurement
PMID 23251661
2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
rs12580745
in
TMEM132D
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs12231737
in
TRAFD1
gene and
Aspartate aminotransferase measurement
PMID 30718733
2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.
rs6899983
in
VARS1
gene and
Aspartate aminotransferase measurement
PMID 30589442
2019 Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
rs4835265
in
ZNF827
gene and
Aspartate aminotransferase measurement
PMID 29403010
2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.