Gene: ACTR2

Alternate names for this Gene: ARP2

Gene Summary: The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 2

Location in Chromosome : 2p14

Description of this Gene: actin related protein 2

Type of Gene: protein-coding

rs17038564 in ACTR2 gene and Adenocarcinoma of lung (disorder) PMID 31326317 2019 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.