Condition: Adenocarcinoma of lung (disorder)
rs3132610 in
ABCF1 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs17038564 in
ACTR2 gene and
Adenocarcinoma of lung (disorder)
PMID 31326317 2019 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.
rs11610143 in
ACVR1B gene and
Adenocarcinoma of lung (disorder)
PMID 26732429 2016 Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women.
rs2004038 in
ADAMTS7 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs71658797 in
AK5 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs1057519781 in
ALK gene and
Adenocarcinoma of lung (disorder)
PMID 22277784 2012 Mechanisms of acquired crizotinib resistance in ALK-rearranged lung Cancers.
PMID 24670165 2014 Ceritinib in ALK-rearranged non-small-cell lung cancer.
PMID 24327273 2014 Furthermore, HSP90 inhibition, as well as the second-generation ALK inhibitor TAE684, demonstrated activity in newly developed lung adenocarcinoma models driven by crizotinib-insensitive EML4-ALK L1196M or F1174L.
PMID 24327273 2014 Furthermore, HSP90 inhibition, as well as the second-generation ALK inhibitor TAE684, demonstrated activity in newly developed lung adenocarcinoma models driven by crizotinib-insensitive EML4-ALK L1196M or F1174L.
rs121913331 in
APC gene and
Adenocarcinoma of lung (disorder)
PMID 18948947 2008 Somatic mutations affect key pathways in lung adenocarcinoma.
PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
rs1057519786 in
ARAF gene and
Adenocarcinoma of lung (disorder)
PMID 24569458 2014 Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma.
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs1023835002 in
B2M;PATL2 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs4808075 in
BABAM1;USHBP1 gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs3117582 in
BAG6;APOM gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs1200399 in
BAZ1A gene and
Adenocarcinoma of lung (disorder)
PMID 31326317 2019 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.
rs7216064 in
BPTF gene and
Adenocarcinoma of lung (disorder)
PMID 27501781 2016 Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.
PMID 31326317 2019 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.
PMID 22797724 2012 A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
rs113488022 in
BRAF gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
PMID 22773810 2012 Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.
rs11571818 in
BRCA2 gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs191524990 in
C1D gene and
Adenocarcinoma of lung (disorder)
PMID 29924316 2018 Genome-wide association study of familial lung cancer.
rs558702 in
C2;ZBTB12;CYP21A2 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs79421398 in
CABLES1 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs1057519918 in
CASC11;MYC gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs104894340 in
CDK4 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs1057519881 in
CDKN2A gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs1011970 in
CDKN2B-AS1 gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs1270942 in
CFB;CYP21A2 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs1051730 in
CHRNA3 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs55781567 in
CHRNA5 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs12441998 in
CHRNB4 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs6495309 in
CHRNB4;CHRNA3 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs11639372 in
CHRNB4;LOC112268142 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs17487514 in
CHRNB4;LOC112268142;RPL18P11 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs31489 in
CLPTM1L gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
PMID 31009812 2019 Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region.
PMID 31326317 2019 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.
rs1057519886 in
CTNNB1 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
rs56113850 in
CYP2A6 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs9387478 in
DCBLD1 gene and
Adenocarcinoma of lung (disorder)
PMID 31326317 2019 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs35772018 in
DCTN4 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs34517439 in
DNAJB4;GIPC2 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs147001633 in
DNMT3A gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs121913229 in
EGFR gene and
Adenocarcinoma of lung (disorder)
PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
PMID 15737014 2005 Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain.
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
PMID 24212795 2011 Glioma Specific Extracellular Missense Mutations in the First Cysteine Rich Region of Epidermal Growth Factor Receptor (EGFR) Initiate Ligand Independent Activation.
PMID 20942962 2010 Clinical implications of novel activating EGFR mutations in malignant peritoneal mesothelioma.
rs1057520012 in
EPHA5 gene and
Adenocarcinoma of lung (disorder)
PMID 16140923 2005 Somatic mutations of the protein kinase gene family in human lung cancer.
rs114807680 in
EPHB1 gene and
Adenocarcinoma of lung (disorder)
PMID 29924316 2018 Genome-wide association study of familial lung cancer.
rs1057519787 in
ERBB2 gene and
Adenocarcinoma of lung (disorder)
PMID 22908275 2012 Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs117151283 in
ERICH6B gene and
Adenocarcinoma of lung (disorder)
PMID 29924316 2018 Genome-wide association study of familial lung cancer.
rs1903003 in
FAM13A gene and
Adenocarcinoma of lung (disorder)
PMID 22797724 2012 A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
rs17400427 in
FAM227B;FGF7 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs7182948 in
FAM227B;LOC105370811 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs1057519895 in
FBXW7 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs1057519045 in
FGFR2 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs121913482 in
FGFR3 gene and
Adenocarcinoma of lung (disorder)
PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
rs2495239 in
FOXP4-AS1 gene and
Adenocarcinoma of lung (disorder)
PMID 22797724 2012 A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
PMID 27501781 2016 In addition, two additional loci, HLA class II at 6p21.32 (rs2179920; P =5.1 × 10(-17), per-allele OR=1.36) and 6p21.1 (FOXP4) (rs2495239; P=3.9 × 10(-9), per-allele OR=1.19) were newly identified as loci associated with EGFR mutation-positive lung adenocarcinoma.
PMID 31326317 2019 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.
PMID 26732429 2016 Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women.
rs56084662 in
FRY gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs1235162 in
GABBR1 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs11632038 in
GALK2 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs1057941 in
GBAP1 gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs11554273 in
GNAS gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs3129791 in
HCG15 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs3130380 in
HCG18;HCG17 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs3132580 in
HCG21;SFTA2;MUCL3 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs2256543 in
HLA-A gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs3132685 in
HLA-A;HCG9 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs115392158 in
HLA-B gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs12601991 in
HNF1B gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs104894230 in
HRAS;LRRC56 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs2036534 in
HYKK gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs121913499 in
IDH1 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs10519198 in
IREB2 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs2316515 in
IRF4 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs11119608 in
KCNH1 gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs121913530 in
KRAS gene and
Adenocarcinoma of lung (disorder)
PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
PMID 25044103 2014 Phase II study of the GI-4000 KRAS vaccine after curative therapy in patients with stage I-III lung adenocarcinoma harboring a KRAS G12C, G12D, or G12V mutation.
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs73110464 in
KRT8 gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs12503223 in
LDB2 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs886424 in
LINC00243 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs67824503 in
LINC00824 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs6988624 in
LINC01414 gene and
Adenocarcinoma of lung (disorder)
PMID 22797724 2012 A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
rs79294676 in
LINC01829;LINC01828 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs148944993 in
LINC01891 gene and
Adenocarcinoma of lung (disorder)
PMID 29924316 2018 Genome-wide association study of familial lung cancer.
rs79655816 in
LINC02392 gene and
Adenocarcinoma of lung (disorder)
PMID 29924316 2018 Genome-wide association study of familial lung cancer.
rs9816551 in
LMCD1-AS1 gene and
Adenocarcinoma of lung (disorder)
PMID 29924316 2018 Genome-wide association study of familial lung cancer.
rs3117143 in
LOC100129636 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs117634027 in
LOC101929727;RNLS gene and
Adenocarcinoma of lung (disorder)
PMID 29924316 2018 Genome-wide association study of familial lung cancer.
rs3813565 in
LOC105370913;CHRNB4 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs2734986 in
LOC105375010 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs9480192 in
LOC105378054 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs75316749 in
LOC107986051 gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs2187668 in
LOC107986589;HLA-DQA2;HLA-DQA1 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs11638372 in
LOC112268142;CHRNB4 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs6897545 in
LOC728613 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs104894226 in
LRRC56;HRAS gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs1057519728 in
MAP2K1 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
rs3099844 in
MICB-DT gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs35535570 in
MIGA1 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs28408315 in
MORF4L1 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs1056562 in
MPZL2 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs55768116 in
MPZL3 gene and
Adenocarcinoma of lung (disorder)
PMID 31326317 2019 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.
rs3131379 in
MSH5;MSH5-SAPCD1 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs885518 in
MTAP gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs2974935 in
MTX1 gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs756091827 in
MYC;CASC11 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs2320614 in
NAF1 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs481519 in
NEK10 gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs1057519920 in
NFE2L2 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs3134942 in
NOTCH4 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs11554290 in
NRAS gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs4236709 in
NRG1 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
PMID 31326317 2019 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.
rs1057519879 in
PATL2;B2M gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs104886003 in
PIK3CA gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs9262143 in
PPP1R18 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs1057519946 in
PPP2R1A gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs397507546 in
PTPN11 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs2608029 in
PVT1 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs9960703 in
RAB31 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs11844632 in
RAD51B gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs80338796 in
RAF1 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs2300206 in
RALY gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs9668978 in
RASSF3;LOC105369803 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs1057519951 in
RHOA gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs9261290 in
RNF39 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs1057519788 in
ROS1 gene and
Adenocarcinoma of lung (disorder)
PMID 23724914 2013 Acquired resistance to crizotinib from a mutation in CD74-ROS1.
rs3184504 in
SH2B3;ATXN2 gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs1057519962 in
SMAD4 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs1057519963 in
SOS1 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs1057520017 in
STK11 gene and
Adenocarcinoma of lung (disorder)
PMID 17676035 2007 LKB1 modulates lung cancer differentiation and metastasis.
rs389884 in
STK19;CYP21A2;DXO gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs3794742 in
SYNGR2 gene and
Adenocarcinoma of lung (disorder)
PMID 26732429 2016 Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women.
rs7750641 in
TCF19 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs78442819 in
TEKT5 gene and
Adenocarcinoma of lung (disorder)
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
rs2293607 in
TERC gene and
Adenocarcinoma of lung (disorder)
PMID 31326317 2019 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.
rs2736100 in
TERT gene and
Adenocarcinoma of lung (disorder)
PMID 20871597 2010 The combined analyses identified two susceptibility loci for lung adenocarcinoma: TERT (rs2736100, combined P = 2.91 × 10⁻¹¹), odds ratio (OR) = 1.27) and TP63 (rs10937405, combined P = 7.26 × 10⁻¹²), OR = 1.31).
PMID 27501781 2016 Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.
PMID 20700438 2010 Since most women in Asia do not smoke, we conducted a genome-wide association study of lung adenocarcinoma in never-smoking females (584 cases, 585 controls) among Han Chinese in Taiwan and found that the most significant association was for rs2736100 on chromosome 5p15.33 (p = 1.30 x 10(-11)).
PMID 22797724 2012 A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
PMID 27393504 2016 Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population.
PMID 31326317 2019 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs1150752 in
TNXB gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs1057519747 in
TP53 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs10937405 in
TP63 gene and
Adenocarcinoma of lung (disorder)
PMID 22797724 2012 A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
PMID 20871597 2010 The combined analyses identified two susceptibility loci for lung adenocarcinoma: TERT (rs2736100, combined P = 2.91 × 10⁻¹¹), odds ratio (OR) = 1.27) and TP63 (rs10937405, combined P = 7.26 × 10⁻¹²), OR = 1.31).
PMID 31326317 2019 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.
PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
PMID 24880342 2014 We also showed an association between common variation at 3q28 (TP63, rs13314271, OR = 1.13, P = 7.22 × 10(-10)) and lung adenocarcinoma that had been previously reported only in Asians.
PMID 27501781 2016 Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.
rs2523987 in
TRIM31-AS1;TRIM31 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs3817963 in
TSBP1-AS1;BTNL2 gene and
Adenocarcinoma of lung (disorder)
PMID 22797724 2012 A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
PMID 27501781 2016 Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.
rs7775397 in
TSBP1-AS1;TSBP1 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs11168936 in
TUBA1C gene and
Adenocarcinoma of lung (disorder)
PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
rs371769427 in
U2AF1 gene and
Adenocarcinoma of lung (disorder)
PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
rs7086803 in
VTI1A gene and
Adenocarcinoma of lung (disorder)
PMID 31326317 2019 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.
rs8321 in
ZNRD1 gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
rs259919 in
ZNRD1ASP gene and
Adenocarcinoma of lung (disorder)
PMID 19836008 2009 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.