Gene: ANAPC4
Alternate names for this Gene: APC4
Gene Summary: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene.
Gene is located in Chromosome: 4
Location in Chromosome : 4p15.2
Description of this Gene: anaphase promoting complex subunit 4
Type of Gene: protein-coding