rs3204689 in ALDH1A2 gene and Degenerative polyarthritis

PMID 24728293 2014 Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.

rs34811474 in ANAPC4 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs7805536 in AVL9 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs3757837 in CAMK2B gene and Degenerative polyarthritis

PMID 23989986 2014 A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip.

rs532464664 in CHADL gene and Degenerative polyarthritis

PMID 28319091 2017 We discovered two rare signals that strongly associate with osteoarthritis total hip replacement: a missense variant, c.1141G>C (p.Asp369His), in the COMP gene (allelic frequency = 0.026%, P = 4.0 × 10^-12, odds ratio (OR) = 16.7) and a frameshift mutation, rs532464664 (p.Val330Glyfs*106), in the CHADL gene that associates through a recessive mode of inheritance (homozygote frequency = 0.15%, P = 4.5 × 10^-18, OR = 7.71).

rs3815148 in COG5 gene and Degenerative polyarthritis

PMID 20112360 2010 The C allele of rs3815148 on chromosome 7q22 (minor allele frequency 23%; intron 12 of the COG5 gene) was associated with a 1.14-fold increased risk (95% confidence interval 1.09-1.19) of knee and/or hand OA (P = 8 x 10(-8)) and also with a 30% increased risk of knee OA progression (95% confidence interval 1.03-1.64) (P = 0.03).

rs2622873 in COL11A1 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs1034762 in COL2A1 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs1355782 in CPNE4 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs317630 in CPSF6 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs2171126 in CRADD gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs12982744 in DOT1L gene and Degenerative polyarthritis

PMID 22566624 2012 Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis.

rs1126464 in DPEP1 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs4730250 in DUS4L gene and Degenerative polyarthritis

PMID 21068099 2011 With a cumulative sample size of 6709 cases and 44 439 controls, one genome-wide significant locus was identified on chromosome 7q22 for knee OA (rs4730250, p=9.2 × 10⁻⁹), thereby confirming its role as a susceptibility locus for OA.

rs11409738 in DYNC1I1 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs798726 in FAM53A gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs10974438 in GLIS3 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs6976 in GNL3;GLT8D1 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs115740542 in H2AC6;H2BC4 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs7810100 in HECW1 gene and Degenerative polyarthritis

PMID 29559693 2018 Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.

rs2856821 in HLA-DPB1;HLA-DPA1 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs10172410 in ITGA4 gene and Degenerative polyarthritis

PMID 21871595 2011 A variant in MCF2L is associated with osteoarthritis.

rs10218792 in KIF26B gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs7941193 in KIRREL3 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs6557013 in LINC02234 gene and Degenerative polyarthritis

PMID 29559693 2018 Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.

rs1998094 in LINC02319 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs11031191 in LOC101928338 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs1404866 in LOC102724680 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs2966417 in LOC105375451 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs919642 in LOC105376225 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs2061027 in LTBP1 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs2820436 in LYPLAL1-AS1 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

PMID 29559693 2018 Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.

rs1417066 in LYPLAL1-AS1;LOC107985272 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs547116051 in MAPT gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs11842874 in MCF2L gene and Degenerative polyarthritis

PMID 21871595 2011 Through large-scale replication, we establish a robust association with SNPs in MCF2L (rs11842874, combined odds ratio [95% confidence interval] 1.17 [1.11-1.23], p = 2.1 × 10(-8)) across a total of 19,041 OA cases and 24,504 controls of European descent.

rs1876836 in MFHAS1 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs10654220 in MPHOSPH9 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs787640 in MYOF gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs11107957 in NAV3 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs7122854 in OPCML gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs7785659 in PDE1C gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs62182810 in RAPH1 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs62262139 in RBM6 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs12901404 in RYR3 gene and Degenerative polyarthritis

PMID 19508968 2009 A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium.

rs62174901 in SCN3A gene and Degenerative polyarthritis

PMID 21871595 2011 A variant in MCF2L is associated with osteoarthritis.

rs528981060 in SCUBE1 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs13107325 in SLC39A8 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs1560707 in SLC44A2 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs11177 in SNORD136;GNL3;SNORD19;PBRM1 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs1566347 in SORBS2 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs2979715 in STMN2 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs10948172 in SUPT3H;LOC101929770 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs17578878 in TBC1D1 gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs3771501 in TGFA gene and Degenerative polyarthritis

PMID 29559693 2018 Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs75621460 in TGFB1 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs10502437 in TMEM241 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs1149620 in TSKU gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

rs2626053 in UNC5C gene and Degenerative polyarthritis

PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs2248393 in UQCC1 gene and Degenerative polyarthritis

PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.