Gene: ANGPTL8

Alternate names for this Gene: C19orf80|PRO1185|PVPA599|RIFL|TD26

Gene Summary:

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.2

Description of this Gene: angiopoietin like 8

Type of Gene: protein-coding

Gene: DOCK6

Alternate names for this Gene: AOS2|ZIR1

Gene Summary: This gene encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with small GTPases and are components of intracellular signaling networks. The encoded protein is a group C DOCK protein and plays a role in actin cytoskeletal reorganization by activating the Rho GTPases Cdc42 and Rac1. Mutations in this gene are associated with Adams-Oliver syndrome 2.

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.2

Description of this Gene: dedicator of cytokinesis 6

Type of Gene: protein-coding

rs2278426 in ANGPTL8;DOCK6 gene and High density lipoprotein measurement PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.

PMID 23505323 2013 Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.

PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.

rs2278426 in ANGPTL8;DOCK6 gene and Low density lipoprotein cholesterol measurement PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.

rs2278426 in ANGPTL8;DOCK6 gene and Serum HDL cholesterol measurement PMID 23505323 2013 Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.

rs2278426 in ANGPTL8;DOCK6 gene and Serum total cholesterol measurement PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.

PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.

rs2278426 in ANGPTL8;DOCK6 gene and Triglycerides measurement PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

rs2278426 in ANGPTL8;DOCK6 gene and Waist-Hip Ratio PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.