Condition: High density lipoprotein measurement
rs10120087 in
ABCA1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 21909109 2011 Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.
PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PMID 26160806 2015 Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3.
PMID 26780889 2016 Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.
PMID 21347282 2011 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 26582766 2016 Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
PMID 27668658 2016 Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.
PMID 18193044 2008 Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
PMID 20864672 2010 Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
PMID 29615537 2018 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.
PMID 19060911 2009 Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
PMID 18193043 2008 Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 26879886 2016 A common variant association study reveals novel susceptibility loci for low HDL-cholesterol levels in ethnic Arabs.
PMID 18193046 2008 Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides.
PMID 23505323 2013 Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.
rs1373067 in
ABCA8 gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
rs4362077 in
ABCC2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs9556465 in
ABCC4 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs9290779 in
ABCC5 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs35060365 in
ABCG4 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs35233375 in
ACADS gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs16942333 in
ACAN gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs17885778 in
ACHE gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs6720034 in
ACOXL gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs11553746 in
ACP1 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs75393320 in
ACP2 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs17189743 in
ACYP2;TSPYL6 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs11960235 in
ADAMTS6 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2062432 in
ADCY5 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs11833801 in
ADGRD1;LOC107984452 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs6987037 in
ADRA1A gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs35381288 in
ADRB3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2035403 in
AFF1 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs12686890 in
AFF2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2936512 in
AGPAT5 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs11568026 in
AGT gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs17237820 in
AGTR2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2347377 in
AKR1B10 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2494748 in
AKT1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs10468017 in
ALDH1A2 gene and
High density lipoprotein measurement
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 21589926 2011 Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.
PMID 21943158 2011 Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 21589926 2011 Here we apply an EMR-based phenotyping approach, within the context of routine care, to replicate several known associations between HDL-C and previously characterized genetic variants: CETP (rs3764261, p = 1.22e-25), LIPC (rs11855284, p = 3.92e-14), LPL (rs12678919, p = 1.99e-7), and the APOA1/C3/A4/A5 locus (rs964184, p = 1.06e-5), all adjusted for age, gender, body mass index (BMI), and smoking status.
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 19060910 2009 Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 19060911 2009 Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
PMID 21909109 2011 Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 24386095 2013 A genome wide association study identifies common variants associated with lipid levels in the Chinese population.
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 18193043 2008 Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs1077835 in
ALDH1A2;LIPC gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 23505323 2013 Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 18193044 2008 Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
PMID 26582766 2016 Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.
PMID 23236364 2012 Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.
PMID 21347282 2011 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
rs261332 in
ALDH1A2;LIPC-AS1;LIPC gene and
High density lipoprotein measurement
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
PMID 29615537 2018 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs17190517 in
ALDH1A2;LIPC;LIPC-AS1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 29615537 2018 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.
PMID 24023260 2013 Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.
rs34183407 in
ALMS1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs17239074 in
ALOX5AP gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs116843064 in
ANGPTL4 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 24507774 2014 Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
PMID 29084231 2017 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
rs2278426 in
ANGPTL8;DOCK6 gene and
High density lipoprotein measurement
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 23505323 2013 Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs78074706 in
ANKS3 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs7162391 in
ANP32A gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs127430 in
APCDD1L-DT gene and
High density lipoprotein measurement
PMID 20838585 2010 Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.
rs7120078 in
APLNR gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs525028 in
APOA1-AS gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs12718465 in
APOA1-AS;APOA1 gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs10750097 in
APOA5 gene and
High density lipoprotein measurement
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 28371326 2017 Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.
PMID 29212154 2017 Moreover, we identified the effect of <i>APOA5</i> rs662799 on triglyceride and HDL, the effect of rs1106475 in the actin filament associated protein 1 like 2 (<i>AFAP1L2</i>) gene on systolic blood pressure, and the effect of rs17667932 in the mediator complex subunit 30 (<i>MED30</i>) gene on fasting glucose.
PMID 23236364 2012 Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.
PMID 26582766 2016 Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.
PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.
rs2075291 in
APOA5;ZPR1 gene and
High density lipoprotein measurement
PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.
rs1041968 in
APOB gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs12721046 in
APOC1 gene and
High density lipoprotein measurement
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs66626994 in
APOC1P1 gene and
High density lipoprotein measurement
PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.
rs2288912 in
APOC2;APOC4-APOC2;APOC4 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
rs138326449 in
APOC3 gene and
High density lipoprotein measurement
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 28548082 2017 Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits.
PMID 30576415 2019 Very low-depth whole-genome sequencing in complex trait association studies.
rs12709889 in
APOC4-APOC2;APOC2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs5157 in
APOC4;APOC4-APOC2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs429358 in
APOE gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 31675503 2019 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
rs9984764 in
APP gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10484766 in
ARG1;MED23 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2238894 in
ARHGAP6 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs6881956 in
ARHGEF28 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs28402213 in
ARHGEF38 gene and
High density lipoprotein measurement
PMID 30498476 2018 Heritability and Genome-Wide Association Study of Plasma Cholesterol in Chinese Adult Twins.
rs1694068 in
ARL15 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs10422058 in
ARMC6 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10305650 in
ARNT gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10832027 in
ARNTL gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs737410 in
ARRB1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs5993889 in
ARVCF;COMT gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2111622 in
ASB3;GPR75-ASB3 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs2606736 in
ATG7 gene and
High density lipoprotein measurement
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
rs3218688 in
ATM gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs1321655 in
ATP1A2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11065633 in
ATP2A2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs12579302 in
ATP2B1 gene and
High density lipoprotein measurement
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs17006555 in
ATP6V1B1;VAX2;ATP6V1B1-AS1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs4766578 in
ATXN2 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs6508974 in
AXL gene and
High density lipoprotein measurement
PMID 31170924 2019 Identification of female-specific genetic variants for metabolic syndrome and its component traits to improve the prediction of metabolic syndrome in females.
rs7000184 in
BAG4;LSM1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs17199964 in
BANK1 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs10239940 in
BAZ1B gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs4987867 in
BCL2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10401176 in
BCL3 gene and
High density lipoprotein measurement
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs13233571 in
BCL7B gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs1519480 in
BDNF-AS gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs6558172 in
BIN3 gene and
High density lipoprotein measurement
PMID 30275891 2018 Family-based genome-wide association of inflammation biomarkers and fenofibrate treatment response in the GOLDN study.
rs10200587 in
BMPR2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs6024947 in
BPI gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs61676547 in
BPTF gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs10790162 in
BUD13 gene and
High density lipoprotein measurement
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10507274 in
C12orf49 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs459193 in
C5orf67 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs10427943 in
CABIN1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2239051 in
CACNA1C gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10891841 in
CADM1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2923084 in
CAND1.11;AMPD3 gene and
High density lipoprotein measurement
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
rs141279119 in
CARMIL2 gene and
High density lipoprotein measurement
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
rs2308939 in
CASP9 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs3208856 in
CBLC gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs884366 in
CCDC162P gene and
High density lipoprotein measurement
PMID 26780889 2016 Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs4130023 in
CCND3 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs10743940 in
CD163 gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs35715143 in
CD22 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs72836561 in
CD300LG gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
rs3211938 in
CD36 gene and
High density lipoprotein measurement
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PMID 23236364 2012 Initial discovery and in silico follow-up in 7,000 additional African American samples, confirmed two novel loci: rs5030359 within ICAM1 is associated with total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) (p = 8.8×10(-7) and p = 1.5×10(-6) respectively) and a nonsense mutation rs3211938 within CD36 is associated with high-density lipoprotein cholesterol (HDL-C) levels (p = 13.5×10(-12)).
rs353616 in
CD44 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs146179438 in
CDC25A gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs34621310 in
CDH16 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs9465848 in
CDKAL1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs3731199 in
CDKN2A gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs1333049 in
CDKN2B-AS1 gene and
High density lipoprotein measurement
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs4253440 in
CEBPB-AS1;CEBPB gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs12740374 in
CELSR2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs192489212 in
CEP164 gene and
High density lipoprotein measurement
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
rs2249105 in
CEP68 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs7726839 in
CEP72 gene and
High density lipoprotein measurement
PMID 23251661 2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
rs267738 in
CERS2 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs4704221 in
CERT1 gene and
High density lipoprotein measurement
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs11076174 in
CETP gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 21909109 2011 Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.
PMID 23505323 2013 Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.
PMID 30911093 2019 Genome-wide association study of blood lipids in Indians confirms universality of established variants.
PMID 21589926 2011 Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks.
PMID 19060911 2009 Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
PMID 31551469 2019 Genetic architecture of human plasma lipidome and its link to cardiovascular disease.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 23236364 2012 Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.
PMID 23696881 2013 Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation.
PMID 20031564 2009 Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.
PMID 18193044 2008 Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
PMID 29404214 2018 Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.
PMID 24023260 2013 Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
PMID 26879886 2016 A common variant association study reveals novel susceptibility loci for low HDL-cholesterol levels in ethnic Arabs.
PMID 18193046 2008 Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides.
PMID 18193043 2008 Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
PMID 30108155 2018 Genome-wide association study identifies novel recessive genetic variants for high TGs in an Arab population.
PMID 28548082 2017 Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits.
PMID 29404214 2018 Two previously implicated loci met genome-wide significance in our SNP-level GWAS in the Nigerian cohort, rs34065661 in <i>CETP</i> associated with HDL cholesterol (<i>P</i> = 9.0 × 10<sup>-10</sup>) and rs1065853 upstream of <i>APOE</i> associated with LDL cholesterol (<i>P</i> = 6.6 × 10<sup>-9</sup>).
PMID 31675503 2019 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa.
PMID 24507774 2014 Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 24886709 2014 Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
PMID 30576415 2019 Very low-depth whole-genome sequencing in complex trait association studies.
PMID 26780889 2016 Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs8006570 in
CHURC1-FNTB;RAB15 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs17085837 in
CLOCK gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs7254723 in
CLPTM1 gene and
High density lipoprotein measurement
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs2925979 in
CMIP gene and
High density lipoprotein measurement
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
rs10948059 in
CNPY3-GNMT;GNMT gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs16880248 in
CNR1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10963012 in
CNTLN gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs1128249 in
COBLL1 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
rs7998875 in
COL4A1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs7121538 in
COPB1 gene and
High density lipoprotein measurement
PMID 26780889 2016 Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.
rs16860432 in
CORIN gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs750134 in
CORO1C gene and
High density lipoprotein measurement
PMID 26879886 2016 A common variant association study reveals novel susceptibility loci for low HDL-cholesterol levels in ethnic Arabs.
rs11574980 in
CPB2-AS1;CPB2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs13076253 in
CPNE4 gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs1047891 in
CPS1 gene and
High density lipoprotein measurement
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
rs7938117 in
CPT1A gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs8142366 in
CRKL gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs1388044873 in
CRPPA;CRPPA-AS1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs333947 in
CSF1 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs28487964 in
CTDSPL2 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs17131304 in
CTH gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs12257093 in
CUBN gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 30498476 2018 Heritability and Genome-Wide Association Study of Plasma Cholesterol in Chinese Adult Twins.
rs79105258 in
CUX2 gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs12784396 in
CWF19L1 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs691960 in
CYP27A1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs33980385 in
CYP2B6 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs702485 in
DAGLB gene and
High density lipoprotein measurement
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs3025393 in
DBH gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs7395581 in
DDB2 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
rs11236530 in
DGAT2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2268840 in
DGKG gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs760242 in
DHCR7 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2074158 in
DHX58 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs10876041 in
DIP2B gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs4844229 in
DLG3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11706108 in
DNAH1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs17404153 in
DNAJC13 gene and
High density lipoprotein measurement
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
rs1011731 in
DNM3;PIGC gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs12979813 in
DOCK6 gene and
High density lipoprotein measurement
PMID 23726366 2013 Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 31393916 2019 Genetically regulated gene expression underlies lipid traits in Hispanic cohorts.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
rs145464906 in
DOCK6;ANGPTL8 gene and
High density lipoprotein measurement
PMID 24507774 2014 Although we did not identify new genes associated with LDL-C, we did identify four low-frequency (frequencies between 0.1% and 2%) variants (ANGPTL8 rs145464906 [c.361C>T; p.Gln121*], PAFAH1B2 rs186808413 [c.482C>T; p.Ser161Leu], COL18A1 rs114139997 [c.331G>A; p.Gly111Arg], and PCSK7 rs142953140 [c.1511G>A; p.Arg504His]) with large effects on HDL-C and/or triglycerides.
rs4495740 in
DOCK7 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs255052 in
DPEP2;DUS2 gene and
High density lipoprotein measurement
PMID 18193043 2008 Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
rs255049 in
DPEP3 gene and
High density lipoprotein measurement
PMID 19060910 2009 Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs12133576 in
DR1 gene and
High density lipoprotein measurement
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs56303487 in
DUS2;DPEP2 gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs192446476 in
DYM gene and
High density lipoprotein measurement
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
rs10478730 in
EDN1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11570255 in
EDN3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10808026 in
EPHA1 gene and
High density lipoprotein measurement
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs1408579 in
ERLIN1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs9341023 in
ESR1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11850375 in
ESR2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10937241 in
ETV5 gene and
High density lipoprotein measurement
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs35926225 in
EVC;CRMP1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs3729639 in
EXOC3L1;E2F4 gene and
High density lipoprotein measurement
PMID 21347282 2011 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
rs7895716 in
EXOC6 gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs12144063 in
EYA3 gene and
High density lipoprotein measurement
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
rs2070850 in
F2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs2243083 in
F2RL1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs9332637 in
F5 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs3093267 in
F7 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs174546 in
FADS1;FADS2 gene and
High density lipoprotein measurement
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
PMID 20694148 2010 A genome-wide association study of the metabolic syndrome in Indian Asian men.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs1535 in
FADS2 gene and
High density lipoprotein measurement
PMID 20694148 2010 A genome-wide association study of the metabolic syndrome in Indian Asian men.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs174547 in
FADS2;FADS1 gene and
High density lipoprotein measurement
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
PMID 29615537 2018 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.
PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 20864672 2010 Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
rs956084 in
FAF1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs12092977 in
FAF1;LOC112268262 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs13133548 in
FAM13A gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs138331350 in
FANCB gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs8017226 in
FANCM gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs12423664 in
FBRSL1 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs62362194 in
FCHO2 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs6601615 in
FDFT1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2845885 in
FLRT1;MACROD1 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs1456649 in
FMN2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs17788930 in
FNBP4 gene and
High density lipoprotein measurement
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
rs74256604 in
FPR1;FPR3 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs17695224 in
FPR3;ZNF577 gene and
High density lipoprotein measurement
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs138570705 in
FRMD5 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
rs1121980 in
FTO gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs10483776 in
FUT8 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs7939352 in
GAB2 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs10818782 in
GABBR2 gene and
High density lipoprotein measurement
PMID 23726366 2013 Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.
rs11248051 in
GAK gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs10127775 in
GALNT2 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 20864672 2010 Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 18193043 2008 Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.
PMID 18193044 2008 Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
rs7222232 in
GAS7 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10149080 in
GCH1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs1260326 in
GCKR gene and
High density lipoprotein measurement
PMID 18454146 2008 Common genetic variation near MC4R is associated with waist circumference and insulin resistance.
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs12449157 in
GFOD2 gene and
High density lipoprotein measurement
PMID 20864672 2010 Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
rs5745571 in
GGNBP1;BAK1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs62491812 in
GIMAP6 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs9826676 in
GNAI2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs76213020 in
GNG2 gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs1129555 in
GPAM gene and
High density lipoprotein measurement
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
rs6573723 in
GPHN gene and
High density lipoprotein measurement
PMID 31393916 2019 Genetically regulated gene expression underlies lipid traits in Hispanic cohorts.
rs78123380 in
GPIHBP1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs7311556 in
GPR19 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs16857586 in
GREB1 gene and
High density lipoprotein measurement
PMID 30108155 2018 Genome-wide association study identifies novel recessive genetic variants for high TGs in an Arab population.
rs16830551 in
GSK3B gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs2749008 in
GSTA2 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs34400162 in
GSTO2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs41266779 in
H4C1 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs11066280 in
HECTD4 gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.
PMID 21909109 2011 Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
rs5745642 in
HGF gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11727676 in
HHIP gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs28366301 in
HLA-DRB1 gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs1144041 in
HMBS gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11555832 in
HMOX1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2244608 in
HNF1A;HNF1A-AS1 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs1800961 in
HNF4A gene and
High density lipoprotein measurement
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11938688 in
HPGDS gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs56076449 in
HSPA4 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs7931970 in
HYOU1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs5030361 in
ICAM1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11999657 in
IFNB1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs622082 in
IGHMBP2 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs4252273 in
IL10RA gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs8134758 in
IL10RB gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs9979085 in
IL10RB-DT;IL10RB gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs17007565 in
IL15 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2232350 in
IL17RB;ACTR8 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs7890572 in
IL1RAPL1 gene and
High density lipoprotein measurement
PMID 20838585 2010 Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.
rs4252040 in
IL1RN gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs6000582 in
IL2RB gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs13306436 in
IL6 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs12089132 in
IL6R-AS1;IL6R gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs1552481 in
IL6R;IL6R-AS1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10940493 in
IL6ST gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs6907508 in
ILRUN gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs2229357 in
INHBC gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs3809114 in
INHBE gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs2322549 in
INPP4B gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs77375493 in
INSL6;JAK2 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs4804411 in
INSR gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs6808104 in
IP6K2 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs4251583 in
IRAK4 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2230667 in
IRF3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs820164 in
ITGB4 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs4905014 in
ITPK1 gene and
High density lipoprotein measurement
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs10761731 in
JMJD1C gene and
High density lipoprotein measurement
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
rs2058804 in
KCTD10 gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 18193043 2008 Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
rs12742376 in
KDF1 gene and
High density lipoprotein measurement
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs7666097 in
KDR gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11870935 in
KPNB1 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs17240378 in
LCAT gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 29084231 2017 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 24507774 2014 Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
rs1109166 in
LCAT;SLC12A4 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs9436735 in
LEPR;LEPROT gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs17615494 in
LINC01122 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs1689788 in
LINC01344 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs2188380 in
LINC01405 gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs856404 in
LINC01524;LOC105372666 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs496300 in
LINC01679 gene and
High density lipoprotein measurement
PMID 20694148 2010 A genome-wide association study of the metabolic syndrome in Indian Asian men.
rs76183280 in
LINC01819 gene and
High density lipoprotein measurement
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
rs338610 in
LINC01967 gene and
High density lipoprotein measurement
PMID 26920376 2016 Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors.
rs900399 in
LINC02029 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs5742626 in
LINC02456;IGF1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs480823 in
LINC02702 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10968576 in
LINGO2 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs17269271 in
LIPC-AS1;ALDH1A2;LIPC gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11858164 in
LIPC-AS1;LIPC;ALDH1A2 gene and
High density lipoprotein measurement
PMID 18193046 2008 Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs1077834 in
LIPC;ALDH1A2 gene and
High density lipoprotein measurement
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 20139978 2010 Genome-wide association study of hematological and biochemical traits in a Japanese population.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PMID 23236364 2012 Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.
PMID 31393916 2019 Genetically regulated gene expression underlies lipid traits in Hispanic cohorts.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 31675503 2019 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa.
PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.
rs17269264 in
LIPC;ALDH1A2;LIPC-AS1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 20864672 2010 Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 26160806 2015 Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 26780889 2016 Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.
rs261338 in
LIPC;LIPC-AS1;ALDH1A2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11082764 in
LIPG gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 26582766 2016 Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
PMID 29084231 2017 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 24507774 2014 Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs359027 in
LMCD1-AS1 gene and
High density lipoprotein measurement
PMID 26879886 2016 A common variant association study reveals novel susceptibility loci for low HDL-cholesterol levels in ethnic Arabs.
rs2602836 in
LOC100507053 gene and
High density lipoprotein measurement
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs4683438 in
LOC100507389 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs114165349 in
LOC101928728;ARID1A gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs7134375 in
LOC105369688 gene and
High density lipoprotein measurement
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
rs11048456 in
LOC105369705 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs7298751 in
LOC105370051 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs28364406 in
LOC105370794;CAPN3 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs7188861 in
LOC105371082;RMI2 gene and
High density lipoprotein measurement
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
rs12753251 in
LOC105371632 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs7209295 in
LOC105371754;HNF1B gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs9913813 in
LOC105371790 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs8065100 in
LOC105371880;MAP2K6 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10438978 in
LOC105372112 gene and
High density lipoprotein measurement
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PMID 20864672 2010 Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
PMID 18193044 2008 Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
PMID 18193043 2008 Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.
PMID 19060911 2009 Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
PMID 20031538 2008 Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 29084231 2017 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.
rs5030339 in
LOC105372272;ICAM1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs4655268 in
LOC105372916 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs4253642 in
LOC105373074;PPARA gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs6733839 in
LOC105373605 gene and
High density lipoprotein measurement
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs13396091 in
LOC105373664 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs56144648 in
LOC105375059;CCND3 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs1358980 in
LOC105375070 gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs12529923 in
LOC105375091 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs11762784 in
LOC105375508 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs17173637 in
LOC105375567;AOC1 gene and
High density lipoprotein measurement
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs17243641 in
LOC105376326;TRAF2;MIR4479 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs7076938 in
LOC105378493 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs2257129 in
LOC105378522 gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs13263508 in
LOC105379311 gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 31201950 2019 Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation, and plasma lipids in the Health and Retirement Study.
rs11987974 in
LOC105379376 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs6728523 in
LOC107984063;CEP68;LINC02245 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs1009360 in
LOC107984063;LINC02245;LINC02576 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs57276302 in
LOC107984444;SCARB1 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs2245477 in
LOC107984782 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs2066152 in
LOC107985272;LYPLAL1-AS1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs10426401 in
LOC107985305;PVR gene and
High density lipoprotein measurement
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs10212938 in
LOC107986321;NPY2R gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs17548308 in
LOC107986556;RIPK1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2268719 in
LOC107986603;TRAM2 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs72961007 in
LOC112267972 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs1461729 in
LOC157273 gene and
High density lipoprotein measurement
PMID 23726366 2013 Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 23505323 2013 Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 21347282 2011 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.
rs1806895 in
LOC283214;DGAT2 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs191555775 in
LPA gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10099160 in
LPL gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PMID 23236364 2012 Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 23202125 2013 Large-scale association analysis identifies new risk loci for coronary artery disease.
PMID 24507774 2014 Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 20864672 2010 Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 23726366 2013 Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.
PMID 18193044 2008 Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
PMID 24386095 2013 A genome wide association study identifies common variants associated with lipid levels in the Chinese population.
PMID 26763881 2016 Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride.
rs34660894 in
LRP1;STAT6 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs5176 in
LRP8 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs143264468 in
LRRC29 gene and
High density lipoprotein measurement
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
rs16922412 in
LYN gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2785990 in
LYPLAL1-AS1 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs2296172 in
MACF1 gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
rs190528931 in
MACROD1 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs10838686 in
MADD gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
rs10501321 in
MADD-AS1;MADD gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs4820323 in
MAFF;PLA2G6 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs1869717 in
MAML3 gene and
High density lipoprotein measurement
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs55707100 in
MAP1A gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs16974082 in
MAP2K6 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs6925103 in
MAP3K5 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs77403571 in
MAPK8IP1 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs11239549 in
MARCHF8 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
rs3773910 in
MBNL1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs11466018 in
MEFV gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2280334 in
MEIS1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs9836225 in
MGLL gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs13379043 in
MIDEAS gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs4074015 in
MIR190B gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs7849420 in
MIR31HG gene and
High density lipoprotein measurement
PMID 24023261 2013 THOC5: a novel gene involved in HDL-cholesterol metabolism.
rs2912054 in
MIR4659A;AGPAT5 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs2070628 in
MIR5188;UBC gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs12446689 in
MIR6863;SLC12A3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs35980686 in
MIR8085;BCL3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs1051921 in
MLXIPL gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs7134594 in
MMAB gene and
High density lipoprotein measurement
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
rs11824953 in
MMP13 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs3746428 in
MMP24-AS1-EDEM2;EDEM2 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs11035019 in
MMP26 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs3025063 in
MMP3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs34722146 in
MSR1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10107815 in
MSRA gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2642438 in
MTARC1 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs12509976 in
MTTP gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs7954144 in
MVK gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs10769254 in
MYBPC3 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2075440 in
MYO1H gene and
High density lipoprotein measurement
PMID 22629316 2012 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
rs146524044 in
MYO5B gene and
High density lipoprotein measurement
PMID 29084231 2017 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.
rs9913758 in
MYOCD;LOC100128006 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs174529 in
MYRF;TMEM258 gene and
High density lipoprotein measurement
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs937254 in
MYZAP;GCOM1 gene and
High density lipoprotein measurement
PMID 21347282 2011 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
rs17696736 in
NAA25 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs10271556 in
NAMPT gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs1940700 in
NCAM1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10402729 in
NCAN gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10504474 in
NCOA2 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs6059988 in
NCOA6;PIGU gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs7218945 in
NCOR1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs406315 in
NECTIN2 gene and
High density lipoprotein measurement
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
PMID 21909109 2011 Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2854322 in
NF1 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs1859311 in
NFATC3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs55878063 in
NFIA gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs12975319 in
NFIC gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs4648086 in
NFKB1;LOC105377347 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2862183 in
NIFK-AS1 gene and
High density lipoprotein measurement
PMID 30670697 2019 Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
rs4743758 in
NIPSNAP3A gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs6810819 in
NOCT gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2975634 in
NOD1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2233455 in
NOL3 gene and
High density lipoprotein measurement
PMID 23236364 2012 Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.
rs9658292 in
NOS1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs1510291 in
NOS1AP gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs8070472 in
NOS2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs34338511 in
NOTCH3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs1788783 in
NPC1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs8086463 in
NPC1;RMC1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10838681 in
NR1H3 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 19060910 2009 Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
rs1879997 in
NR1I2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs17100234 in
NR3C1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10954843 in
NRG1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs7081526 in
NRG3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs28932178 in
NSD1 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs480392 in
NTNG1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10900522 in
NUCKS1 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs10852553 in
NUP93 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
rs1124324 in
NUTF2 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.
PMID 19060911 2009 Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
rs2072134 in
OAS3 gene and
High density lipoprotein measurement
PMID 31006500 2020 Protein and fat intake interacts with the haplotype of PTPN11_rs11066325, RPH3A_rs886477, and OAS3_rs2072134 to modulate serum HDL concentrations in middle-aged people.
PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.
rs2233548 in
OMP;CAPN5 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs139917442 in
OR4C46 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs11230661 in
OR4P1P gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs35396069 in
OSBP2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10494363 in
OTUD7B;MTMR11 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs11603691 in
P2RX3 gene and
High density lipoprotein measurement
PMID 26879886 2016 A common variant association study reveals novel susceptibility loci for low HDL-cholesterol levels in ethnic Arabs.
rs1790082 in
P2RY2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs4660293 in
PABPC4 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 29615537 2018 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.
rs17513135 in
PABPC4;PABPC4-AS1 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs186808413 in
PAFAH1B2 gene and
High density lipoprotein measurement
PMID 24507774 2014 Although we did not identify new genes associated with LDL-C, we did identify four low-frequency (frequencies between 0.1% and 2%) variants (ANGPTL8 rs145464906 [c.361C>T; p.Gln121*], PAFAH1B2 rs186808413 [c.482C>T; p.Ser161Leu], COL18A1 rs114139997 [c.331G>A; p.Gly111Arg], and PCSK7 rs142953140 [c.1511G>A; p.Arg504His]) with large effects on HDL-C and/or triglycerides.
rs483465 in
PCCB gene and
High density lipoprotein measurement
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
rs7679 in
PCIF1 gene and
High density lipoprotein measurement
PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.
rs6130975 in
PCIF1;ZNF335 gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs12801636 in
PCNX3 gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
rs142953140 in
PCSK7 gene and
High density lipoprotein measurement
PMID 24507774 2014 Although we did not identify new genes associated with LDL-C, we did identify four low-frequency (frequencies between 0.1% and 2%) variants (ANGPTL8 rs145464906 [c.361C>T; p.Gln121*], PAFAH1B2 rs186808413 [c.482C>T; p.Ser161Leu], COL18A1 rs114139997 [c.331G>A; p.Gly111Arg], and PCSK7 rs142953140 [c.1511G>A; p.Arg504His]) with large effects on HDL-C and/or triglycerides.
rs12289096 in
PDE2A;PDE2A-AS1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs7313422 in
PDE3A gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs1037378 in
PDE3B gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs4691380 in
PDGFC gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs12274248 in
PDGFD gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs7993724 in
PDX1;PLUT gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs8138057 in
PDXP gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs34940240 in
PEPD gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs35426314 in
PER3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2934956 in
PGAP3 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs11571151 in
PGR-AS1;PGR gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs12601079 in
PGS1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs4883201 in
PHC1 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs7847628 in
PHF19 gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs184392658 in
PIGT;LOC105372631 gene and
High density lipoprotein measurement
PMID 29084231 2017 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.
rs6059932 in
PIGU gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs3729693 in
PIK3CA gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs41278045 in
PLA2G12A gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs17688076 in
PLA2G15 gene and
High density lipoprotein measurement
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs133027 in
PLA2G6 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs4251884 in
PLAUR gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs35169799 in
PLCB3 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs6710896 in
PLCD4 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs760762 in
PLCG1 gene and
High density lipoprotein measurement
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs1147169 in
PLCL1 gene and
High density lipoprotein measurement
PMID 26879886 2016 A common variant association study reveals novel susceptibility loci for low HDL-cholesterol levels in ethnic Arabs.
rs139271800 in
PLIN1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs435306 in
PLTP gene and
High density lipoprotein measurement
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2294915 in
PNPLA3 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs2307111 in
POC5 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs5744680 in
POLK gene and
High density lipoprotein measurement
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs3213833 in
POLR3A gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11217785 in
POU2F3;LOC105369531 gene and
High density lipoprotein measurement
PMID 23726366 2013 Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.
rs4253624 in
PPARA gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2299869 in
PPARD gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs117350179 in
PPARG gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs17264866 in
PPIEL gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs139097404 in
PPIP5K1P1-CATSPER2;CATSPER2 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs1126930 in
PRKAG1;DDN-AS1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs1881626 in
PRKAG2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs3923913 in
PRKAR2A gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs75862065 in
PRKRA gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs4911477 in
PROCR;MMP24-AS1-EDEM2 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs16942887 in
PSKH1 gene and
High density lipoprotein measurement
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs20549 in
PSMB10 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs599839 in
PSRC1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 23202125 2013 Large-scale association analysis identifies new risk loci for coronary artery disease.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs12242772 in
PTEN gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11066325 in
PTPN11 gene and
High density lipoprotein measurement
PMID 31006500 2020 Protein and fat intake interacts with the haplotype of PTPN11_rs11066325, RPH3A_rs886477, and OAS3_rs2072134 to modulate serum HDL concentrations in middle-aged people.
rs235314 in
PTTG1IP gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs11613352 in
R3HDM2 gene and
High density lipoprotein measurement
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs2967605 in
RAB11B gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.
rs73591976 in
RANBP10 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
rs7730898 in
RANBP17 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs143876112 in
RBM39 gene and
High density lipoprotein measurement
PMID 31201950 2019 Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation, and plasma lipids in the Health and Retirement Study.
rs2013208 in
RBM5;RBM6 gene and
High density lipoprotein measurement
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs111439884 in
RBM6 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs7897379 in
REEP3 gene and
High density lipoprotein measurement
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
rs11571111 in
REN gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs4765127 in
RFLNA;ZNF664;ZNF664-RFLNA gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
rs12055786 in
RGS17 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs4657836 in
RGS2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs28577594 in
RILPL2 gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs17513478 in
RIPK1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs183208454 in
RIPOR1 gene and
High density lipoprotein measurement
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
rs12594733 in
RORA gene and
High density lipoprotein measurement
PMID 24886709 2014 Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.
rs4455790 in
RP1L1 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs721772 in
RPAP1 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs2384034 in
RPH3A gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
PMID 31006500 2020 Protein and fat intake interacts with the haplotype of PTPN11_rs11066325, RPH3A_rs886477, and OAS3_rs2072134 to modulate serum HDL concentrations in middle-aged people.
rs7899453 in
RPS24 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11644601 in
RRN3;PDXDC1 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs12145743 in
RRNAD1 gene and
High density lipoprotein measurement
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs2489629 in
RSPO3 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs2834707 in
RUNX1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs10120653 in
RXRA gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs34879232 in
SARM1;SLC46A1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs10773003 in
SBNO1 gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs61743199 in
SCAF1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs10773105 in
SCARB1 gene and
High density lipoprotein measurement
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
rs67053123 in
SCARB1;LOC105370050 gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs3917781 in
SELP gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs60839105 in
SEMA3C gene and
High density lipoprotein measurement
PMID 27036123 2016 Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels.
rs7632505 in
SEMA5B gene and
High density lipoprotein measurement
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs16862734 in
SERP1;EIF2A gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs895953 in
SETD1B gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
PMID 30525989 2018 Bivariate Genome-Wide Association Scan Identifies 6 Novel Loci Associated With Lipid Levels and Coronary Artery Disease.
rs2290547 in
SETD2 gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs11960617 in
SGCD gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs147122512 in
SGSM3 gene and
High density lipoprotein measurement
PMID 31393916 2019 Genetically regulated gene expression underlies lipid traits in Hispanic cohorts.
rs7310615 in
SH2B3 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs3184504 in
SH2B3;ATXN2 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs6710091 in
SH3YL1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs530885291 in
SIDT2 gene and
High density lipoprotein measurement
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
rs11216162 in
SIK3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 24886709 2014 Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
PMID 31170924 2019 In addition, two genome-wide significant female-specific associations (P<sub>meta</sub> < 5X10<sup>- 8</sup>) were detected for rs455489 in DSCAM for fasting plasma glucose (FPG) and for rs7115583 in SIK3 for high-density lipoprotein cholesterol (HDLC).
rs2306363 in
SIPA1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs17100926 in
SIPA1L1 gene and
High density lipoprotein measurement
PMID 23251661 2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
rs151159962 in
SKA1 gene and
High density lipoprotein measurement
PMID 29084231 2017 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.
rs11079810 in
SKAP1 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs1138429 in
SLC12A3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs2292318 in
SLC12A4 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs4285028 in
SLC15A2 gene and
High density lipoprotein measurement
PMID 26920376 2016 Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors.
rs11804107 in
SLC16A1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs3753600 in
SLC1A7 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs16928809 in
SLC22A18 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs10405178 in
SLC25A42 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs6694527 in
SLC2A5 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs6759518 in
SLC30A3 gene and
High density lipoprotein measurement
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs13107325 in
SLC39A8 gene and
High density lipoprotein measurement
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
rs7212502 in
SLC6A4 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11875522 in
SMAD4 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2863973 in
SMPD3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs538509310 in
SNHG22 gene and
High density lipoprotein measurement
PMID 29084231 2017 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.
rs141588480 in
SNTA1 gene and
High density lipoprotein measurement
PMID 30670697 2019 Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
rs4722593 in
SNX10 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs17138358 in
SNX13 gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs2231555 in
SOCS6 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs12247406 in
SORCS1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs6486291 in
SOX6 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11170538 in
SP1 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs2373459 in
SPIC gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs2303975 in
SPON1 gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs2483058 in
SRGAP2 gene and
High density lipoprotein measurement
PMID 23031429 2012 We found one locus associated with intra-pair differences in high-density lipoprotein cholesterol, rs2483058 in an intron of SRGAP2, where twins carrying the C allele are more sensitive to environmental factors(P=3.98 x 10-8).
rs76970536 in
ST3GAL4 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs13326165 in
STAB1 gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs151105710 in
STAG1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 27286809 2016 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
rs2555592 in
STARD13-AS;STARD13 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2764627 in
STARD13;STARD13-AS gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11869286 in
STARD3 gene and
High density lipoprotein measurement
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs8039217 in
STARD9 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10401969 in
SUGP1 gene and
High density lipoprotein measurement
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs10411413 in
SUGP2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2281279 in
SULF2 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs290986 in
SYK gene and
High density lipoprotein measurement
PMID 26920376 2016 Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors.
rs12394306 in
SYN1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs12165603 in
SYN3;TIMP3 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs508487 in
TAGLN;PCSK7 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs10185855 in
TBC1D8 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs199929635 in
TBCA gene and
High density lipoprotein measurement
PMID 30498476 2018 Heritability and Genome-Wide Association Study of Plasma Cholesterol in Chinese Adult Twins.
rs11974409 in
TBL2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs931992 in
TCAP gene and
High density lipoprotein measurement
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
rs4506565 in
TCF7L2 gene and
High density lipoprotein measurement
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs4650994 in
TEX35;C1orf220 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs11568746 in
TGFBR1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs13306848 in
THBD gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs8135828 in
THOC5 gene and
High density lipoprotein measurement
PMID 24023261 2013 The combined meta-analysis of the three study cohorts (n(HDL) = 6041; n(LDL) = 5,995; n(TG) = 6,087) revealed a novel association for a variant in THOC5 (rs8135828) with serum HDL-C levels (P = 1.78 × 10⁻⁷; Z-score = -5.221).
rs2044753 in
THRB gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs8177358 in
TIRAP gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs5743616 in
TLR1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs6685271 in
TMED5 gene and
High density lipoprotein measurement
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs76116020 in
TMED6 gene and
High density lipoprotein measurement
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs3173615 in
TMEM106B gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs840763 in
TMEM117 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs34311866 in
TMEM175 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
rs102275 in
TMEM258 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 20694148 2010 A genome-wide association study of the metabolic syndrome in Indian Asian men.
rs174537 in
TMEM258;MYRF gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs1117816 in
TMPRSS11E gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs1045241 in
TNFAIP8 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs235216 in
TNFRSF1B gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs9943924 in
TNFSF11 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs6094214 in
TNNC2 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11652616 in
TOB1-AS1 gene and
High density lipoprotein measurement
PMID 31201950 2019 Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation, and plasma lipids in the Health and Retirement Study.
rs1038026 in
TOMM40 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 19060911 2009 Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 23202125 2013 Large-scale association analysis identifies new risk loci for coronary artery disease.
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs8078476 in
TP53 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs150844304 in
TP53BP1 gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs2880301 in
TPTE2 gene and
High density lipoprotein measurement
PMID 30263053 2018 Genome-wide association study for multiple phenotype analysis.
PMID 30275891 2018 Family-based genome-wide association of inflammation biomarkers and fenofibrate treatment response in the GOLDN study.
rs6777217 in
TRANK1 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs7901017 in
TRDMT1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs11921179 in
TRH gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs17369400 in
TRIM2 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs79775842 in
TRIO gene and
High density lipoprotein measurement
PMID 30498476 2018 Heritability and Genome-Wide Association Study of Plasma Cholesterol in Chinese Adult Twins.
rs2293889 in
TRPS1 gene and
High density lipoprotein measurement
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
rs10911505 in
TSEN15 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs56121005 in
TSPAN16 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs149492745 in
TTBK2 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs1215112 in
TTC39B gene and
High density lipoprotein measurement
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 20864672 2010 Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs148149124 in
TUBGCP4 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs5471 in
TXNL4B;HP gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs11873890 in
TYMS gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs10790519 in
UBASH3B gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs181360 in
UBE2L3 gene and
High density lipoprotein measurement
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
rs10744826 in
UBE3B gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30698716 2019 Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
rs34696509 in
UVRAG gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs1874148 in
VCL gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs1000879 in
VIL1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs7122226 in
VPS11 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs16958751 in
VPS4A;COG8 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs12938449 in
VPS53 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs7516521 in
WNT2B gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs2075847 in
WTAPP1;MMP1 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs1811069 in
YDJC gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs10789752 in
ZC3H12C;RDX gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs10408163 in
ZC3H4 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.
rs12369179 in
ZCCHC8 gene and
High density lipoprotein measurement
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs2809270 in
ZFAND5 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
rs7190256 in
ZFHX3 gene and
High density lipoprotein measurement
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
rs4465830 in
ZNF335 gene and
High density lipoprotein measurement
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
rs4805755 in
ZNF507 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs11652146 in
ZNF652 gene and
High density lipoprotein measurement
PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
rs863750 in
ZNF664-RFLNA;RFLNA gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
rs7307277 in
ZNF664;RFLNA;ZNF664-RFLNA gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
rs8142788 in
ZNRF3 gene and
High density lipoprotein measurement
PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
rs11604424 in
ZPR1 gene and
High density lipoprotein measurement
PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 21386085 2011 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.
PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
PMID 30911093 2019 Genome-wide association study of blood lipids in Indians confirms universality of established variants.
PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.
PMID 23726366 2013 Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.
PMID 30926973 2019 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.
PMID 21589926 2011 Here we apply an EMR-based phenotyping approach, within the context of routine care, to replicate several known associations between HDL-C and previously characterized genetic variants: CETP (rs3764261, p = 1.22e-25), LIPC (rs11855284, p = 3.92e-14), LPL (rs12678919, p = 1.99e-7), and the APOA1/C3/A4/A5 locus (rs964184, p = 1.06e-5), all adjusted for age, gender, body mass index (BMI), and smoking status.
PMID 20864672 2010 Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.
PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.
rs2072560 in
ZPR1;APOA5 gene and
High density lipoprotein measurement
PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.