Gene: APLNR

Alternate names for this Gene: AGTRL1|APJ|APJR|HG11

Gene Summary: This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.

Gene is located in Chromosome: 11

Location in Chromosome : 11q12.1

Description of this Gene: apelin receptor

Type of Gene: protein-coding