Gene: ARAF

Alternate names for this Gene: A-RAF|ARAF1|PKS2|RAFA1

Gene Summary: This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: X

Location in Chromosome : Xp11.3

Description of this Gene: A-Raf proto-oncogene, serine/threonine kinase

Type of Gene: protein-coding

rs1057519786 in ARAF gene and Adenocarcinoma of lung (disorder) PMID 24569458 2014 Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma.

PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519786 in ARAF gene and Cutaneous Melanoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519786 in ARAF gene and Papillary renal cell carcinoma, sporadic PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.