Gene: ARID3B

Alternate names for this Gene: BDP|DRIL2

Gene Summary: This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification.

Gene is located in Chromosome: 15

Location in Chromosome : 15q24.1

Description of this Gene: AT-rich interaction domain 3B

Type of Gene: protein-coding

rs8025068 in ARID3B gene and Body Height PMID 31562340 2019 Characterizing rare and low-frequency height-associated variants in the Japanese population.

rs11072494 in ARID3B gene and Cleft Palate PMID 28054174 2017 Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.

rs11072494 in ARID3B gene and Cleft upper lip PMID 28054174 2017 Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.

rs74781061 in ARID3B gene and Endometriosis PMID 28881265 2017 New variants near RHOJ and C2, HLA-DRA region and susceptibility to endometriosis in the Polish population-The genome-wide association study.

rs10459648 in ARID3B gene and Goldenhar Syndrome PMID 26853712 2016 Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia.