Gene: ARPIN-AP3S2

Alternate names for this Gene: ARPIN|C15orf38|C15orf38-AP3S2

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring C15orf38 (chromosome 15 open reading frame 38) and AP3S2 (adaptor-related protein complex 3, sigma 2 subunit) genes. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product.

Gene is located in Chromosome: 15

Location in Chromosome : 15q26.1

Description of this Gene: ARPIN-AP3S2 readthrough

Type of Gene: protein-coding

Gene: AP3S2

Alternate names for this Gene: AP3S3|sigma3b

Gene Summary:

Gene is located in Chromosome: 15

Location in Chromosome : 15q26.1

Description of this Gene: adaptor related protein complex 3 subunit sigma 2

Type of Gene: protein-coding

Gene: MIR5094

Alternate names for this Gene: -

Gene Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Gene is located in Chromosome: 15

Location in Chromosome : 15q26.1

Description of this Gene: microRNA 5094

Type of Gene: ncRNA

rs11435035 in ARPIN-AP3S2;AP3S2;MIR5094 gene and Diabetes Mellitus, Non-Insulin-Dependent PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.