Condition: Diabetes Mellitus, Non-Insulin-Dependent
rs348330 in
ABCB10 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs4275659 in
ABCB9 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs757110 in
ABCC8 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
rs72928364 in
ABI3BP gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs505922 in
ABO gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
rs60780116 in
ACSL1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs7804216 in
ACTR3C gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs111558778 in
ADAMTS9-AS2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31049640 2019 Genome-wide association study of type 2 diabetes in Africa.
PMID 18372903 2008 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs2838820 in
ADARB1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30130595 2018 Pilot genome-wide association study identifying novel risk loci for type 2 diabetes in a Maya population.
rs11708067 in
ADCY5 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 22693455 2012 Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs995447 in
ADGRL3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23670970 2013 Genetic modifiers of cystic fibrosis-related diabetes.
rs73284431 in
AGMO gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31049640 2019 Genome-wide association study of type 2 diabetes in Africa.
rs1535435 in
AHI1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17668382 2007 Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium.
rs121434593 in
AKT2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 19164855 2009 Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis.
PMID 22962670 2012 Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline.
PMID 15166380 2004 A family with severe insulin resistance and diabetes due to a mutation in AKT2.
PMID 23492873 2013 Recommendations from the EGAPP Working Group: does genomic profiling to assess type 2 diabetes risk improve health outcomes?
rs9931702 in
AKTIP gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs6898559 in
ALDH7A1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs1406230 in
ALK gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31264924 2019 A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity.
rs33981001 in
ANK1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
rs515071 in
ANK1;MIR486-1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22456796 2012 Combined meta-analysis using directly genotyped data for stages 1 and 2 revealed that rs515071 in ANK1 and rs7656416 near MGC21675 were associated with type 2 diabetes in the Japanese population at the genome-wide significant level (P < 5 × 10(-8)).
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs2278524 in
ANKFY1;CYB5D2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs1061813 in
ANKH gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs2028299 in
AP3S2;ARPIN-AP3S2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 21874001 2011 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs2476601 in
AP4B1-AS1;PTPN22 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30254083 2018 First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes.
rs4420638 in
APOC1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs11602873 in
ARAP1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs2246012 in
ARG1;MED23 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs10189773 in
ARHGAP15 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
rs12719778 in
ARHGAP39 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs4865796 in
ARL15 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs74570061 in
ARL9 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs8031576 in
ARPIN-AP3S2;AP3S2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs11435035 in
ARPIN-AP3S2;AP3S2;MIR5094 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs73934724 in
ASB3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs28265 in
ASCC2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs116549635 in
ASCL2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs1027700 in
ATF6 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
rs68062313 in
ATP8B2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs16879003 in
ATXN1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs112674299 in
ATXN7 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs2292662 in
ATXN7;SCAANT1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs6947395 in
AUTS2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs12454712 in
BCL2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs79128089 in
BCL9 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs75229567 in
BEST3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs72804453 in
BICC1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs9648716 in
BRAF gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs377457 in
C16orf74 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
rs9891146 in
C17orf58 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs11763876 in
C1GALT1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs115884658 in
C2;CYP21A2;EHMT2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
rs256903 in
C5orf67 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 26961502 2016 Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 27189021 2016 Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility.
rs3900856 in
C5orf67;LOC105378978 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs10278 in
CALCOCO2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs12569857 in
CAMK1D gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs2633310 in
CAMK2G gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs3794205 in
CAMKK2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
rs1193179 in
CAMTA1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17293876 2007 A genome-wide association study identifies novel risk loci for type 2 diabetes.
PMID 19184112 2009 Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans.
rs2134223 in
CASR gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs137945355 in
CCDC149 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs115321690 in
CCHCR1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs12299509 in
CCND2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs11063069 in
CCND2-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
rs76895963 in
CCND2-AS1;CCND2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs12010175 in
CCNQ gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22961080 2013 A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.
rs1049549 in
CD81;TSSC4 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28254843 2017 Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
rs10508438 in
CDC123 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
rs1040558 in
CDKAL1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 17463249 2007 Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
PMID 19056611 2009 Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.
PMID 20818381 2010 A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
PMID 17460697 2007 A variant in CDKAL1 influences insulin response and risk of type 2 diabetes.
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 19401414 2009 Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.
PMID 19734900 2009 Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.
PMID 18711366 2008 SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.
PMID 18372903 2008 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
PMID 17463248 2007 A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
PMID 23945395 2014 Genome-wide association study identifies three novel loci for type 2 diabetes.
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
PMID 22961080 2013 A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 26961502 2016 Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 22693455 2012 Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
PMID 25483131 2014 T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility.
PMID 27189021 2016 Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility.
PMID 23575436 2013 New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population.
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
PMID 17554300 2007 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
PMID 28406950 2017 A total of 3 SNPs [rs9465871 (CDKAL1), rs10761745 (JMJD1C), and rs163177 (KCNQ1)] were selected as candidate SNPs related to T2D.
rs2820001 in
CDKAL1;LOC107986577 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
rs564398 in
CDKN2B-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17463249 2007 Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs1063192 in
CDKN2B;CDKN2B-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs71313049 in
CELSR1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs11759026 in
CENPW gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs7572857 in
CEP68 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs104893649 in
CERKL;NEUROD1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 10545951 1999 Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus.
PMID 23492873 2013 Recommendations from the EGAPP Working Group: does genomic profiling to assess type 2 diabetes risk improve health outcomes?
PMID 22962670 2012 Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline.
rs79768058 in
CFAP77 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs11706588 in
CHCHD6 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31264924 2019 A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity.
rs7274168 in
CHMP4B gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs11591741 in
CHUK gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs34030778 in
CLN8 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs12596103 in
CMIP gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs6633421 in
CNKSR2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs2779772 in
CNTLN gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 21799836 2011 A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese.
rs10195252 in
COBLL1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs77792157 in
CPA1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs189118455 in
CPEB3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23945395 2014 Genome-wide association study identifies three novel loci for type 2 diabetes.
rs10261386 in
CPED1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30130595 2018 Pilot genome-wide association study identifying novel risk loci for type 2 diabetes in a Maya population.
rs73069940 in
CTBP1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
rs7656416 in
CTBP1-DT gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22456796 2012 The association of rs7656416 with type 2 diabetes disappeared after conditioning on rs6815464.
rs72501962 in
CTBP1-DT;CTBP1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs13239186 in
CTTNBP2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs7921488 in
CUBN gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23945395 2014 Genome-wide association study identifies three novel loci for type 2 diabetes.
rs145010525 in
DARS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs3791020 in
DARS2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
rs136867 in
DEPDC5 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30130595 2018 Pilot genome-wide association study identifying novel risk loci for type 2 diabetes in a Maya population.
rs17168486 in
DGKB gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
rs838720 in
DGKD gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs1149833 in
DLEU1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31264924 2019 A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs963740 in
DLEU7;DLEU1;DLEU1-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs1861612 in
DNER gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 24101674 2014 A genome-wide association study in American Indians implicates DNER as a susceptibility locus for type 2 diabetes.
rs6951280 in
DOCK4 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs1894299 in
DUSP9 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs181126208 in
EDARADD gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs6059662 in
EIF2S2;RALY gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs10420309 in
EML2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs138945390 in
ENPP7P10;LOC105369250 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs16829174 in
EPC2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs11819995 in
ETS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs67232546 in
ETS1-AS1;ETS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs34773007 in
EXOC6 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
rs6066138 in
EYA2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs144226500 in
FAAH2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs12031188 in
FAF1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs9940149 in
FAM234A gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs80333777 in
FBXL7 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs7660590 in
FBXW7 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs1783598 in
FCHSD2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
rs2607653 in
FGF14 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs3135911 in
FGFR4 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs3214606 in
FLJ13224;SINHCAF gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs1653969 in
FOXP1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs448792 in
FRY gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs806215 in
FSCN3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
rs75260059 in
FTCDNL1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 25760438 2015 First genome-wide association study in an Australian aboriginal population provides insights into genetic risk factors for body mass index and type 2 diabetes.
rs11075989 in
FTO gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 17463249 2007 Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
PMID 19056611 2009 In the "obese-type 2 diabetes" scan, FTO variants had the strongest type 2 diabetes effect (rs8050136: relative risk [RR] 1.49 [95% CI 1.34-1.66], P = 1.3 x 10(-13)), with only weak evidence for TCF7L2 (rs7901695 RR 1.21 [1.09-1.35], P = 0.001).
PMID 17463248 2007 A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 26961502 2016 Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 22693455 2012 Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
PMID 17554300 2007 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
rs2055942 in
GABRA4 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23937595 2013 A genome-wide search for type 2 diabetes susceptibility genes in an extended Arab family.
rs6606859 in
GABRG3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs3794991 in
GATAD2A gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs989099 in
GCC1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
rs1799884 in
GCK gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23575436 2013 New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population.
rs2908289 in
GCK;LOC105375257 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
rs1260326 in
GCKR gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
rs12481568 in
GDAP1L1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 21874001 2011 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
rs115505614 in
GIN1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs11671664 in
GIPR gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs1017568 in
GLIS3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 22961080 2013 A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs9394574 in
GLP1R gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs78761021 in
GLP2R gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
rs117267808 in
GP2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs7916840 in
GPR158 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29703844 2018 A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.
rs9973676 in
GPR55 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs11787792 in
GPSM1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23945395 2014 Genome-wide association study identifies three novel loci for type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs75536691 in
GRB14 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs10886471 in
GRK5 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22961080 2013 In nondiabetic individuals, the T2D risk-increasing allele of RASGRP1-rs7403531 was also associated with higher HbA(1c) and lower homeostasis model assessment of β-cell function (P = 0.03 and 0.0209, respectively), whereas the T2D risk-increasing allele of GRK5-rs10886471 was also associated with higher fasting insulin (P = 0.0169) but not with fasting glucose.
rs2074356 in
HECTD4 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23575436 2013 New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population.
rs3383 in
HIVEP2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs2071479 in
HLA-DOB gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs9273363 in
HLA-DQB1-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 30254083 2018 First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes.
rs1063355 in
HLA-DQB1-AS1;HLA-DQB1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs9273401 in
HLA-DQB1;HLA-DQB1-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 27189021 2016 Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility.
rs115918645 in
HLA-DRB9 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
rs12910361 in
HMG20A gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 21490949 2011 Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 22693455 2012 Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 21874001 2011 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
rs1480474 in
HMGA2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs9668162 in
HMGA2-AS1;HMGA2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
rs343092 in
HMGA2;HMGA2-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 25102180 2014 Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
rs1169299 in
HNF1A gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
rs7305618 in
HNF1A-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 21573907 2011 Genome-wide association study of type 2 diabetes in a sample from Mexico City and a meta-analysis of a Mexican-American sample from Starr County, Texas.
rs1169288 in
HNF1A-AS1;HNF1A gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs1800574 in
HNF1A;HNF1A-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs10908278 in
HNF1B gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 23492873 2013 Recommendations from the EGAPP Working Group: does genomic profiling to assess type 2 diabetes risk improve health outcomes?
PMID 22962670 2012 Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline.
PMID 12161522 2002 The S465R mutation was found in 0.5% of our patients with common type 2 diabetes and thus may be a rare genetic risk factor contributing to the development of type 2 diabetes rather than MODY5.
PMID 21874001 2011 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 22961080 2013 A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs137853337 in
HNF4A gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 9449683 1998 A missense mutation in hepatocyte nuclear factor-4 alpha, resulting in a reduced transactivation activity, in human late-onset non-insulin-dependent diabetes mellitus.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 21874001 2011 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
rs4810426 in
HNF4A-AS1;HNF4A gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs4812831 in
HNF4A;HNF4A-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 21874001 2011 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
rs16988333 in
HORMAD2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs41278853 in
HORMAD2-AS1;MTMR3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs75444904 in
HPR;TXNL4B gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29572449 2018 Genetic markers for urine haptoglobin is associated with decline in renal function in type 2 diabetes in East Asians.
rs1061810 in
HSD17B12 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
rs2421943 in
IDE gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17460697 2007 A variant in CDKAL1 influences insulin response and risk of type 2 diabetes.
rs11705729 in
IGF2BP2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 27189021 2016 Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 21573907 2011 Genome-wide association study of type 2 diabetes in a sample from Mexico City and a meta-analysis of a Mexican-American sample from Starr County, Texas.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 23945395 2014 Genome-wide association study identifies three novel loci for type 2 diabetes.
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 20818381 2010 A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
PMID 21874001 2011 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
PMID 22693455 2012 Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 18372903 2008 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 19401414 2009 Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.
PMID 26961502 2016 Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively.
PMID 17463249 2007 Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
PMID 17463248 2007 A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
PMID 18711366 2008 SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs11390176 in
IL13RA1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs137848 in
IL17REL gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
rs3842770 in
INS-IGF2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 25102180 2014 Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
rs149483638 in
INS-IGF2;IGF2;IGF2-AS gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28838971 2017 A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes.
rs689 in
INS;INS-IGF2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30254083 2018 First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes.
rs121913150 in
INSR gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22962670 2012 Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline.
PMID 23492873 2013 Recommendations from the EGAPP Working Group: does genomic profiling to assess type 2 diabetes risk improve health outcomes?
PMID 1470163 1992 [Insulin receptor Arg1131-->Gln: a novel mutation in the catalytic loop of insulin receptor observed in insulin resistant diabetes].
PMID 1607076 1992 NIDDM associated with mutation in tyrosine kinase domain of insulin receptor gene.
PMID 7657032 1995 Frequency of mutations of insulin receptor gene in Japanese patients with NIDDM.
rs17359493 in
INTS8 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 25102180 2014 Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
rs329122 in
JADE2;LOC107986451 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs1635852 in
JAZF1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 27189021 2016 Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 18372903 2008 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
rs2074314 in
KCNJ11 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 18372903 2008 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 17463249 2007 Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
PMID 17463248 2007 A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
PMID 19056611 2009 Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.
rs111669836 in
KCNK7 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
rs163171 in
KCNQ1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 20818381 2010 A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
PMID 28406950 2017 Among them, rs10761745 (JMJD1C) and rs163177 (KCNQ1) were prospectively associated with T2D.
PMID 20174558 2010 A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese.
PMID 21799836 2011 A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 28254843 2017 Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 22961080 2013 A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 23945395 2014 Genome-wide association study identifies three novel loci for type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 18711367 2008 The association of KCNQ1 with type 2 diabetes was replicated in populations of Korean, Chinese and European ancestry as well as in two independent Japanese populations, and meta-analysis with a total of 19,930 individuals (9,569 cases and 10,361 controls) yielded a P value of 1.7 x 10(-42) (OR = 1.40; 95% CI = 1.34-1.47) for rs2237892.
PMID 19401414 2009 Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.
PMID 20174558 2010 We also confirmed that variants in KCNQ1 were associated with T2D risk, with the strongest signal at rs2237895 (P = 9.65x10(-10); OR = 1.29, 95% CI = 1.19-1.40).
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
PMID 24390345 2014 Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico.
PMID 18711366 2008 The association of these SNPs with type 2 diabetes was replicated in samples from Singaporean (additive model: rs2237895, P = 8.5 x 10(-3); OR = 1.14, rs2237897, P = 2.4 x 10(-4); OR = 1.22) and Danish populations (additive model: rs2237895, P = 3.7 x 10(-11); OR = 1.24, rs2237897, P = 1.2 x 10(-4); OR = 1.36).
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 25102180 2014 Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
PMID 21874001 2011 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
PMID 24101674 2014 A genome-wide association study in American Indians implicates DNER as a susceptibility locus for type 2 diabetes.
rs77402029 in
KCNQ1;KCNQ1OT1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs117601636 in
KCNQ1OT1;KCNQ1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 25102180 2014 Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs111248619 in
KCNQ3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31324766 2019 ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response.
rs10882095 in
KIF11 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
rs2276853 in
KIF9-AS1;KIF9 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs79310463 in
KSR2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs7240767 in
LAMA1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 22693455 2012 A variant (rs8090011) in the LAMA1 gene was associated with type 2 diabetes in lean cases (P = 8.4×10⁻⁹, OR = 1.13 [95% CI 1.09-1.18]), and this association was stronger than that in obese cases (P = 0.04, OR = 1.03 [95% CI 1.00-1.06]).
rs9494266 in
LINC00271 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17668382 2007 Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium.
rs1561927 in
LINC00824 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
rs1904756 in
LINC00844;LOC102724768 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
rs114176593 in
LINC01010 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs13417036 in
LINC01122 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs12518099 in
LINC01339 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 19734900 2009 Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.
rs8134546 in
LINC01426 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs200803778 in
LINC02010 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs10034465 in
LINC02484 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs1009358 in
LINC02576;LOC107984063;LINC02245 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs11636249 in
LINC02694 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs10555080 in
LINC02841 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31127053 2019 A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies.
rs7357773 in
LINGO2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs9847133 in
LMCD1-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31049640 2019 Genome-wide association study of type 2 diabetes in Africa.
rs13331385 in
LOC100506281;CTRB1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
rs2796441 in
LOC101927502 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs80196932 in
LOC101927919;NUS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs3806185 in
LOC101928264;DUSP23 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
rs112209655 in
LOC102724680 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs1449245 in
LOC102724710 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30470734 2018 Evidence for genetic contribution to the increased risk of type 2 diabetes in schizophrenia.
rs3916765 in
LOC102725019 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22693455 2012 Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
rs9309245 in
LOC105369165 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 26818947 2016 Combined data from discovery and subsequent validation analyses (23,399 T2D cases and 31,722 controls) identify 7 new loci with genome-wide significance (P<5 × 10(-8)), rs1116357 near CCDC85A, rs147538848 in FAM60A, rs1575972 near DMRTA1, rs9309245 near ASB3, rs67156297 near ATP8B2, rs7107784 near MIR4686 and rs67839313 near INAFM2.
rs6728803 in
LOC105369168 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
rs11615866 in
LOC105369617 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 24974787 2015 A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain.
rs11048456 in
LOC105369705 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs10842994 in
LOC105369709 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs11113776 in
LOC105369965;WSCD2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs11616380 in
LOC105370275 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 20862305 2010 Identification of new genetic risk variants for type 2 diabetes.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
rs61960346 in
LOC105370289;LINC00333 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs234146 in
LOC105370650;LINC02291 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22961080 2013 A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.
rs117897666 in
LOC105370892 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29703844 2018 A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.
rs4932143 in
LOC105370965 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs7213402 in
LOC105371525 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30130595 2018 Pilot genome-wide association study identifying novel risk loci for type 2 diabetes in a Maya population.
rs10911021 in
LOC105371642;LINC01344 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23982368 2013 Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes.
rs79349575 in
LOC105371814;SUMO2P17 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
rs6506900 in
LOC105372049 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs6515236 in
LOC105372562 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs4817543 in
LOC105372787 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30130595 2018 Pilot genome-wide association study identifying novel risk loci for type 2 diabetes in a Maya population.
rs12617659 in
LOC105373585 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs6723108 in
LOC105373629;TMEM163 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23209189 2013 We identified a new type 2 diabetes-associated locus at 2q21, with the lead signal being rs6723108 (odds ratio 1.31; P = 3.32 × 10⁻⁹).
rs1535500 in
LOC105375047;KCNK16;KCNK17 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs34247110 in
LOC105375047;KCNK17;KCNK16 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs2396083 in
LOC105375069;LOC107986598 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
rs2049477 in
LOC105375132 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30130595 2018 Pilot genome-wide association study identifying novel risk loci for type 2 diabetes in a Maya population.
rs10258162 in
LOC105375490 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
rs4731420 in
LOC105375494 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 23945395 2014 Genome-wide association study identifies three novel loci for type 2 diabetes.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs10260148 in
LOC105375508 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
rs11558471 in
LOC105375716;SLC30A8 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
rs6434742 in
LOC105376755 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
rs59457600 in
LOC105377097;LINC02030 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30130595 2018 Pilot genome-wide association study identifying novel risk loci for type 2 diabetes in a Maya population.
rs11154178 in
LOC105377982;TRDN gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28672053 2017 A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers.
rs9384331 in
LOC105378054 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs11199755 in
LOC105378521 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs527320094 in
LOC105378797 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs17428041 in
LOC105379318 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 24974787 2015 A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain.
rs73206603 in
LOC107984625 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29703844 2018 A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.
rs34715063 in
LOC107984739 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs115689251 in
LOC107985068 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs2820426 in
LOC107985272;LYPLAL1-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs6754498 in
LOC107985783 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs115990514 in
LOC107986066 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs4686471 in
LOC107986166 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs10946406 in
LOC107986577;CDKAL1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
rs9369425 in
LOC107986598 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
rs9362054 in
LOC107986620;LINC01611 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 25364816 2014 A genome-wide association study for diabetic retinopathy in a Japanese population: potential association with a long intergenic non-coding RNA.
rs91 in
LOC107986777 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs4258054 in
LOC107986989;GLIS3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
rs10114341 in
LOC107987099 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs11774915 in
LOC157273 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs12629668 in
LOC440982;ZIC1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31264924 2019 A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity.
rs7578326 in
LOC646736 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs328 in
LPL gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs148347825 in
LRFN2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs7900112 in
LRMDA gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs13268287 in
LRP12 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
rs113533135 in
LRP1B gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs16826069 in
MACF1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs11247990 in
MAEA gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 23945395 2014 Genome-wide association study identifies three novel loci for type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs17797882 in
MAF gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
rs11095909 in
MAGEC3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30130595 2018 Pilot genome-wide association study identifying novel risk loci for type 2 diabetes in a Maya population.
rs113805659 in
MAGI2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs2303700 in
MAP2K7 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs80028505 in
MAPK14 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28672053 2017 A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers.
rs3761980 in
MAPK14;SLC26A8 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28672053 2017 A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers.
rs119489103 in
MAPK8IP1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23492873 2013 Recommendations from the EGAPP Working Group: does genomic profiling to assess type 2 diabetes risk improve health outcomes?
PMID 22962670 2012 Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline.
rs3864095 in
MASP1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30130595 2018 Pilot genome-wide association study identifying novel risk loci for type 2 diabetes in a Maya population.
rs4472028 in
MBNL1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs367943 in
MCC gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
rs4988198 in
MCM6 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs3773159 in
MGLL gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 21799836 2011 A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese.
rs140386498 in
MINDY1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs243018 in
MIR4432HG gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs10169613 in
MIR4435-2HG gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs34954281 in
MIR4773-2;LOC101929319;TNFAIP6 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31264924 2019 A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity.
rs4077129 in
MIR6821;PIM3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs665268 in
MLX gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs140751051 in
MNX1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs1727313 in
MPHOSPH9 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
rs73354145 in
MRPL12 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs1127787 in
MRPS35 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 23945395 2014 Genome-wide association study identifies three novel loci for type 2 diabetes.
rs7709909 in
MSH3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs10830963 in
MTNR1B gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 28254843 2017 Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
rs59811240 in
MTSS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs7845219 in
NDUFAF6 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs6857 in
NECTIN2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 27189021 2016 Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility.
rs41277236 in
NEUROG3;LOC101929021 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs244415 in
NFAT5 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs6021276 in
NFATC2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs2857605 in
NFKBIL1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs12549902 in
NKX6-3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
rs115092681 in
NLGN1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs10923931 in
NOTCH2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 18372903 2008 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs3913535 in
NOX4 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30178632 2018 A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes.
rs2238367 in
NPRL3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
rs141864436 in
NRXN1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs10146997 in
NRXN3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs7442201 in
NSG1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs1573219 in
NTRK2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
rs11073752 in
NTRK3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31127053 2019 A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies.
rs11098676 in
NUDT6 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs11066453 in
OAS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23575436 2013 New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population.
rs61953351 in
OASL gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs275856 in
OSBPL1A gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 25483131 2014 T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility.
rs17214144 in
OSBPL3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs9911983 in
OSBPL7 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs12624924 in
OSER1-DT;OSER1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 21874001 2011 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
rs16988852 in
OSER1;OSER1-DT gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 21874001 2011 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
rs17513135 in
PABPC4;PABPC4-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 27189021 2016 Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility.
rs10823559 in
PALD1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30130595 2018 Pilot genome-wide association study identifying novel risk loci for type 2 diabetes in a Maya population.
rs17054480 in
PALLD gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 26915486 2016 Genetic analysis of advanced glycation end products in the DHS MIND study.
rs35658696 in
PAM gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs114202595 in
PAX4 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22962670 2012 Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline.
PMID 23492873 2013 Recommendations from the EGAPP Working Group: does genomic profiling to assess type 2 diabetes risk improve health outcomes?
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs16996185 in
PBX4 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs12027542 in
PCNX2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 21490949 2011 Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.
rs6598475 in
PCSK6 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30470734 2018 Evidence for genetic contribution to the increased risk of type 2 diabetes in schizophrenia.
rs11864909 in
PDILT gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29703844 2018 A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.
rs59490629 in
PDSS2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs11410487 in
PELO;ITGA1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs10406327 in
PEPD gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
rs112284299 in
PEX5L gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs8093481 in
PIEZO2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 26169365 2015 Susceptible gene of stasis-stagnation constitution from genome-wide association study related to cardiovascular disturbance and possible regulated traditional Chinese medicine.
rs10100265 in
PINX1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs940904 in
PITPNM2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs6691335 in
PKN2-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
rs35169799 in
PLCB3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs10510110 in
PLEKHA1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs738409 in
PNPLA3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs2307111 in
POC5 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs3130501 in
POU5F1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
rs11709077 in
PPARG gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
rs6904271 in
PPIL6 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
rs35678078 in
PPP2R2C gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs12910825 in
PRC1-AS1;PRC1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
rs2191651 in
PRIM2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
rs10224002 in
PRKAG2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29703844 2018 A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.
rs2075423 in
PROX1;PROX1-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs254271 in
PRPF31 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29650774 2018 Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes.
rs6693796 in
PRRX1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs3816157 in
PSMD6 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
rs599839 in
PSRC1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
rs1127655 in
PTGFRN;CD101 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs11926707 in
PTH1R gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs6780013 in
PTPN23 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs17584499 in
PTPRD gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 20174558 2010 A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
rs4272321 in
PTPRN2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs10087241 in
PURG gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs7570971 in
RAB3GAP1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23209189 2013 Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.
rs11656775 in
RAI1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs9892728 in
RAMP2-AS1;RAMP2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs4729854 in
RASA4DP gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs11073333 in
RASGRP1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 22961080 2013 In nondiabetic individuals, the T2D risk-increasing allele of RASGRP1-rs7403531 was also associated with higher HbA(1c) and lower homeostasis model assessment of β-cell function (P = 0.03 and 0.0209, respectively), whereas the T2D risk-increasing allele of GRK5-rs10886471 was also associated with higher fasting insulin (P = 0.0169) but not with fasting glucose.
rs143838781 in
RBM19 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs1020731 in
RBMS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 20418489 2010 Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes.
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
rs2299383 in
RELN gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs3818329 in
RGS13 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31264924 2019 A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity.
rs679992 in
RGS7 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 25102180 2014 Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
rs77972797 in
RHOBTB1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs10507349 in
RNF6 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs73607972 in
RPGRIP1L gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs1531343 in
RPSAP52 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 26961502 2016 Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs2258238 in
RPSAP52;HMGA2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs35742417 in
RREB1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs62069176 in
RTN4RL1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29621232 2018 Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey.
rs4823182 in
SAMM50 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs1060105 in
SBNO1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs993380 in
SCD5 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs75639901 in
SCGN gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs3731600 in
SCTR gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs1048886 in
SDHAF4 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 21490949 2011 Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.
rs6762208 in
SENP2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs2236033 in
SFI1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
rs17053082 in
SGCD gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
rs9552911 in
SGCG gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23300278 2013 On combined meta-analysis in Sikh populations (n = 7,329; 3,354 case subjects), we identified a novel locus in association with T2D at 13q12 represented by a directly genotyped intronic SNP (rs9552911, P = 1.82 × 10⁻⁸) in the SGCG gene.
rs3184504 in
SH2B3;ATXN2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30254083 2018 First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes.
rs147538848 in
SINHCAF gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 26818947 2016 Combined data from discovery and subsequent validation analyses (23,399 T2D cases and 31,722 controls) identify 7 new loci with genome-wide significance (P<5 × 10(-8)), rs1116357 near CCDC85A, rs147538848 in FAM60A, rs1575972 near DMRTA1, rs9309245 near ASB3, rs67156297 near ATP8B2, rs7107784 near MIR4686 and rs67839313 near INAFM2.
rs74577409 in
SLC16A11 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 24390345 2014 Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico.
rs312457 in
SLC16A13 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23945395 2014 Genome-wide association study identifies three novel loci for type 2 diabetes.
rs2421897 in
SLC1A2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs7512462 in
SLC26A9 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23670970 2013 Genetic modifiers of cystic fibrosis-related diabetes.
rs4077468 in
SLC26A9-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23670970 2013 Genetic modifiers of cystic fibrosis-related diabetes.
rs1342061 in
SLC26A9-AS1;SLC26A9 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23670970 2013 Genetic modifiers of cystic fibrosis-related diabetes.
rs1342063 in
SLC26A9;SLC26A9-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23670970 2013 Genetic modifiers of cystic fibrosis-related diabetes.
rs8192675 in
SLC2A2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
PMID 27500523 2016 Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin.
rs121434581 in
SLC2A4 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23492873 2013 Recommendations from the EGAPP Working Group: does genomic profiling to assess type 2 diabetes risk improve health outcomes?
PMID 1521731 1992 Insulin receptor and insulin-responsive glucose transporter (GLUT 4) mutations and polymorphisms in a Welsh type 2 (non-insulin-dependent) diabetic population.
PMID 22962670 2012 Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline.
PMID 1918382 1991 Analysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitus.
PMID 1756912 1991 Molecular scanning of insulin-responsive glucose transporter (GLUT4) gene in NIDDM subjects.
rs531347476 in
SLC30A8 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 29703844 2018 A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.
rs13266634 in
SLC30A8;LOC105375716 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 27189021 2016 Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility.
PMID 17293876 2007 A genome-wide association study identifies novel risk loci for type 2 diabetes.
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
PMID 19401414 2009 Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 17463248 2007 A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
PMID 17463249 2007 Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 21874001 2011 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 23945395 2014 Genome-wide association study identifies three novel loci for type 2 diabetes.
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 19734900 2009 Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 22693455 2012 Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 26961502 2016 Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
rs7674212 in
SLC9B2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
rs2548724 in
SLCO4C1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
rs150626020 in
SND1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs41308713 in
SNHG17 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs9285630 in
SNX7 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs11107116 in
SOCS2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs7561798 in
SPHKAP gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs187150787 in
SPPL3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs34669198 in
SRBD1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 25760438 2015 First genome-wide association study in an Australian aboriginal population provides insights into genetic risk factors for body mass index and type 2 diabetes.
rs4925115 in
SREBF1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
rs391300 in
SRR gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 20174558 2010 A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
rs1050226 in
SSR1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
rs12040333 in
ST3GAL3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs16861329 in
ST6GAL1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 21874001 2011 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs2631781 in
ST6GALNAC3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs77757620 in
STARD9 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs17405722 in
STAT3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs7214842 in
STX8 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs10401969 in
SUGP1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
rs2073721 in
TCF19 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs10885409 in
TCF7L2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 19184112 2009 Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans.
PMID 17293876 2007 A genome-wide association study identifies novel risk loci for type 2 diabetes.
PMID 20818381 2010 A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 17463248 2007 A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
PMID 17460697 2007 A variant in CDKAL1 influences insulin response and risk of type 2 diabetes.
PMID 17668382 2007 Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium.
PMID 27189021 2016 Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility.
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 25483131 2014 T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility.
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 31324766 2019 ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response.
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 17554300 2007 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
PMID 17463249 2007 Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 21347282 2011 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
PMID 23670970 2013 Genetic modifiers of cystic fibrosis-related diabetes.
PMID 19734900 2009 Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.
PMID 30470734 2018 Evidence for genetic contribution to the increased risk of type 2 diabetes in schizophrenia.
PMID 28254843 2017 Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 19056611 2009 Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.
PMID 19401414 2009 Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 21874001 2011 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 31049640 2019 Fine-mapping of the TCF7L2 locus suggested one type 2 diabetes association signal shared between Europeans and Africans (indexed by rs7903146) and a distinct African-specific signal (indexed by rs17746147).
PMID 20694148 2010 A genome-wide association study of the metabolic syndrome in Indian Asian men.
PMID 24390345 2014 Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico.
PMID 22101970 2012 Subsequent GWAS using data from five institutions replicated the TCF7L2 gene variant (rs7903146) previously associated with T2D.
PMID 22693455 2012 Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 23945395 2014 Genome-wide association study identifies three novel loci for type 2 diabetes.
PMID 26961502 2016 Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively.
PMID 23209189 2013 Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 25102180 2014 Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
PMID 18372903 2008 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
rs302864 in
TEX14 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs4715207 in
TFAP2B gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs11466334 in
TGFB1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31049640 2019 Genome-wide association study of type 2 diabetes in Africa.
rs3738441 in
TGFBR3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs4072825 in
TH gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31324766 2019 ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs10203174 in
THADA gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 18372903 2008 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
rs7180092 in
THSD4 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
rs58542926 in
TM6SF2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs621341 in
TMEM163 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23209189 2013 Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.
rs147689733 in
TNKS2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 23945395 2014 Genome-wide association study identifies three novel loci for type 2 diabetes.
rs1320164 in
TP53INP1;NDUFAF6 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
rs72928978 in
TPCN2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs58847779 in
TRIOBP gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs11635657 in
TRPM1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30130595 2018 Pilot genome-wide association study identifying novel risk loci for type 2 diabetes in a Maya population.
rs910049 in
TSBP1-AS1;TSBP1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
rs2050188 in
TSBP1;TSBP1-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
rs1955163 in
TSPAN15 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs377247337 in
TSPAN3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs7961581 in
TSPAN8 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 18372903 2008 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
rs9966620 in
TTC39C gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31264924 2019 A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity.
rs2032844 in
TTLL6 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs115025532 in
TTLL8 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs1758632 in
UBAP2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs1011754 in
UBE2E2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 20818381 2010 A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
rs1495130 in
UBE2E2-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
rs13094957 in
UBE2E2;LOC105376991 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
rs1058018 in
UBE2Z gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 27362418 2016 A Powerful Procedure for Pathway-Based Meta-analysis Using Summary Statistics Identifies 43 Pathways Associated with Type II Diabetes in European Populations.
PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs1182389 in
UBE3C gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs13333226 in
UMOD gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29703844 2018 A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.
rs28485846 in
UNC5D gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28672053 2017 A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers.
rs982077 in
USP3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs1825307 in
USP48 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs3749456 in
UVSSA gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
rs1802295 in
VPS26A gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 21874001 2011 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
rs12899811 in
VPS33B gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
rs2680830 in
VSNL1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29221444 2017 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
rs1801212 in
WFS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 19734900 2009 Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.
rs551640889 in
XYLT1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs2908282 in
YKT6 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs10077431 in
YTHDC2 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs4457053 in
ZBED3-AS1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs9470794 in
ZFAND3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22158537 2011 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
rs17265513 in
ZHX3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
rs12571751 in
ZMIZ1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 31118516 2019 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs2304130 in
ZNF101 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 22885922 2012 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
rs148316037 in
ZNF257 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
rs2294120 in
ZNF34 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs825476 in
ZNF664-RFLNA;RFLNA gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
rs7810240 in
ZNF775 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 28736931 2018 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
rs1465146591 in
ZRANB3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 31324766 2019 ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response.
rs35260355 in
ZSCAN20 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 26629533 2015 A Genome-wide Association Study Provides Evidence of Sex-specific Involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) With Diabetic Neuropathic Pain.
rs1045493 in
ZSWIM3 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 17463246 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
rs113547729 in
ZZEF1 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
PMID 28566273 2017 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.