Gene: AXL

Alternate names for this Gene: ARK|JTK11|Tyro7|UFO

Gene Summary: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.2

Description of this Gene: AXL receptor tyrosine kinase

Type of Gene: protein-coding