Gene: BABAM2
Alternate names for this Gene: BRCC4|BRCC45|BRE
Gene Summary: This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.
Gene is located in Chromosome: 2
Location in Chromosome : 2p23.2
Description of this Gene: BRISC and BRCA1 A complex member 2
Type of Gene: protein-coding