Condition: Bipolar Disorder
rs4148087 in
ABCG1 gene and
Bipolar Disorder
PMID 26433762 2016 A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region.
rs56031956 in
ACTL7A gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs16875288 in
ADAMTS16;LOC101929200 gene and
Bipolar Disorder
PMID 24039173 2013 Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia.
rs1521470 in
ADCY1 gene and
Bipolar Disorder
PMID 29121268 2018 Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
rs10512928 in
ADCY2 gene and
Bipolar Disorder
PMID 24618891 2014 Genome-wide association study reveals two new risk loci for bipolar disorder.
PMID 27890468 2017 Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis.
rs10884920 in
ADD3 gene and
Bipolar Disorder
PMID 28072414 2017 Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder.
rs142370491 in
AKAP6 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs58630086 in
ALOX12-AS1;ALOX12P2 gene and
Bipolar Disorder
PMID 24322204 2014 Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.
rs10509129 in
ANK3 gene and
Bipolar Disorder
PMID 24618891 2014 Genome-wide association study reveals two new risk loci for bipolar disorder.
PMID 28072414 2017 Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder.
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
PMID 18711365 2008 To identify susceptibility loci for bipolar disorder, we tested 1.8 million variants in 4,387 cases and 6,209 controls and identified a region of strong association (rs10994336, P = 9.1 x 10(-9)) in ANK3 (ankyrin G).
PMID 20351715 2011 Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.
PMID 23637625 2013 Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate.
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
PMID 21926972 2011 Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs6006893 in
ARHGAP8;PRR5-ARHGAP8 gene and
Bipolar Disorder
PMID 24882193 2014 Bipolar disorder with comorbid binge eating history: a genome-wide association study implicates APOB.
PMID 29391396 2018 The meta-analysis provided genome-wide significant evidence of association between single nucleotide polymorphisms (SNPs) in PRR5-ARHGAP8 and BE in BD cases (rs726170 OR = 1.91, P = 3.05E-08).
rs146330533 in
ARHGEF10L gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs76317718 in
ARHGEF15 gene and
Bipolar Disorder
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
rs907162 in
ASAP2 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs9608816 in
ASCC2 gene and
Bipolar Disorder
PMID 27890468 2017 Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis.
rs735931 in
ATP2B2 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs11125080 in
ATP6V1E2 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs7567409 in
BABAM2 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs17810023 in
BCKDHB gene and
Bipolar Disorder
PMID 29391396 2018 Bipolar disorder with binge eating behavior: a genome-wide association study implicates PRR5-ARHGAP8.
rs11624408 in
BCL11B gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs188839109 in
C11orf21;TSPAN32 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs10896135 in
C11orf80 gene and
Bipolar Disorder
PMID 21926972 2011 Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
rs4800149 in
CABLES1 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs1006737 in
CACNA1C gene and
Bipolar Disorder
PMID 23070075 2013 Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
PMID 18711365 2008 Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.
PMID 20351715 2011 Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.
PMID 24280982 2014 Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.
PMID 23637625 2013 Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate.
PMID 21926972 2011 Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
PMID 28072414 2017 Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder.
PMID 30626913 2019 Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression.
rs10848642 in
CACNA1C;CACNA1C-AS4 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs10744560 in
CACNA1C;CACNA1C-IT3 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs2799573 in
CACNB2 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs2070615 in
CACNB3 gene and
Bipolar Disorder
PMID 21926972 2011 Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
rs10511083 in
CADM2 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs17498753 in
CAMKMT gene and
Bipolar Disorder
PMID 21738484 2011 Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes.
rs6484218 in
CAND1.11;AMPD3 gene and
Bipolar Disorder
PMID 20713499 2010 Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression.
rs12052005 in
CCDC102B gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs141252918 in
CCDC170 gene and
Bipolar Disorder
PMID 31164008 2019 GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.
rs34486957 in
CCDC175 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs3804640 in
CD47 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs12594483 in
CDAN1 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs3761218 in
CDC25B gene and
Bipolar Disorder
PMID 21254220 2011 Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder.
rs11756438 in
CEP85L gene and
Bipolar Disorder
PMID 27890468 2017 Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis.
rs12661338 in
CEP85L;LOC105377971 gene and
Bipolar Disorder
PMID 27890468 2017 Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis.
rs150404479 in
CFAP57;EBNA1BP2;LOC105378685 gene and
Bipolar Disorder
PMID 24322204 2014 Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.
rs2934442 in
CGNL1 gene and
Bipolar Disorder
PMID 21305692 2011 Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder.
rs6942227 in
CMAHP gene and
Bipolar Disorder
PMID 29121268 2018 Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
rs7914558 in
CNNM2 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs26318 in
COMMD10 gene and
Bipolar Disorder
PMID 31164008 2019 GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.
rs185880008 in
CPNE8 gene and
Bipolar Disorder
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
rs10503253 in
CSMD1 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
PMID 24166486 2013 GWAS meta analysis identifies TSNARE1 as a novel Schizophrenia / Bipolar susceptibility locus.
rs9662615 in
CSMD2 gene and
Bipolar Disorder
PMID 26806518 2016 Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.
rs2242663 in
CTSF gene and
Bipolar Disorder
PMID 19416921 2009 Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.
rs7904579 in
CUBN gene and
Bipolar Disorder
PMID 29391396 2018 Bipolar disorder with binge eating behavior: a genome-wide association study implicates PRR5-ARHGAP8.
rs1819204 in
CUL4A gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs62433108 in
DCBLD1 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs1054442 in
DDN gene and
Bipolar Disorder
PMID 27329760 2016 Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.
rs105633 in
DELE1;PCDH12 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs6993270 in
DEPTOR gene and
Bipolar Disorder
PMID 26297903 2016 Genetics of long-term treatment outcome in bipolar disorder.
rs1012053 in
DGKH gene and
Bipolar Disorder
PMID 17486107 2008 A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder.
rs7296288 in
DHH gene and
Bipolar Disorder
PMID 21926972 2011 Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
PMID 23070075 2013 Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.
rs11773103 in
DMTF1 gene and
Bipolar Disorder
PMID 20351715 2011 Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.
rs17158930 in
DOCK4 gene and
Bipolar Disorder
PMID 25944848 2015 Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs.
rs10488140 in
EGFR gene and
Bipolar Disorder
PMID 18317468 2008 Whole-genome association study of bipolar disorder.
rs2517959 in
ERBB2;PGAP3 gene and
Bipolar Disorder
PMID 27329760 2016 Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.
rs28456 in
FADS1;FADS2 gene and
Bipolar Disorder
PMID 28115744 2018 In the present GWAS (Phase I/II), which included 2964 BD and 61 887 control subjects from the Japanese population, we detected a novel susceptibility locus at 11q12.2 (rs28456, P=6.4 × 10<sup>-9</sup>), a region known to contain regulatory genes for plasma lipid levels (FADS1/2/3).
rs174576 in
FADS2 gene and
Bipolar Disorder
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
rs12226877 in
FADS2;FADS1 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs79403677 in
FAM177A1 gene and
Bipolar Disorder
PMID 29121268 2018 Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
rs6728642 in
FAM178B gene and
Bipolar Disorder
PMID 29121268 2018 Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
rs1985671 in
FBLN1 gene and
Bipolar Disorder
PMID 22365631 2012 Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.
rs4870888 in
FER1L6;FER1L6-AS2 gene and
Bipolar Disorder
PMID 31164008 2019 GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.
rs548181 in
FEZ1;STT3A-AS1;STT3A gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs1805576 in
FXR1 gene and
Bipolar Disorder
PMID 26433762 2016 A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region.
rs7833426 in
GFRA2 gene and
Bipolar Disorder
PMID 26806518 2016 Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.
rs221798 in
GIGYF1 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs3733041 in
GLT8D1 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs3755798 in
GLT8D1;SPCS1 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs2289247 in
GNL3;SNORD69 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs61123830 in
GRAMD1B gene and
Bipolar Disorder
PMID 29121268 2018 Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
rs11647445 in
GRIN2A gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs10748045 in
GRIP1 gene and
Bipolar Disorder
PMID 24964207 2014 Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study.
rs9577511 in
GRTP1 gene and
Bipolar Disorder
PMID 31164008 2019 GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.
rs17150022 in
GSDME gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs2273684 in
GSS gene and
Bipolar Disorder
PMID 23070075 2013 Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.
rs59724122 in
GULOP;EPHX2 gene and
Bipolar Disorder
PMID 29121268 2018 Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
rs112114764 in
HDAC5 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs61549860 in
HDAC9 gene and
Bipolar Disorder
PMID 26806518 2016 Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.
rs2524005 in
HLA-A gene and
Bipolar Disorder
PMID 22688191 2012 Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.
rs209474 in
HLA-DMA gene and
Bipolar Disorder
PMID 29121268 2018 Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
rs1480380 in
HLA-DMB gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs884301 in
HLF gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs329674 in
IGSF9B gene and
Bipolar Disorder
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
rs17018311 in
INTS7 gene and
Bipolar Disorder
PMID 22365631 2012 Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.
rs142754383 in
IPO8 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs72745470 in
IQCH-AS1;IQCH gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs1042779 in
ITIH1 gene and
Bipolar Disorder
PMID 19416921 2009 Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
PMID 28072414 2017 Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder.
PMID 24166486 2013 GWAS meta analysis identifies TSNARE1 as a novel Schizophrenia / Bipolar susceptibility locus.
rs2535629 in
ITIH3 gene and
Bipolar Disorder
PMID 30626913 2019 Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression.
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
PMID 23070075 2013 Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.
rs329319 in
JADE2 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs2054399 in
KCNMB2-AS1;KCNMB2 gene and
Bipolar Disorder
PMID 22688191 2012 Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.
rs10058613 in
KDM3B gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs63722863 in
KIF15 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs62173322 in
KLHL23 gene and
Bipolar Disorder
PMID 31164008 2019 GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.
rs10875914 in
KMT2D gene and
Bipolar Disorder
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
rs61945387 in
KSR2 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs17680579 in
LAMA4-AS1 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs12493050 in
LAMP3 gene and
Bipolar Disorder
PMID 26503763 2016 Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.
PMID 21254220 2011 Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder.
rs12669727 in
LHFPL3;LHFPL3-AS1 gene and
Bipolar Disorder
PMID 26806518 2016 Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.
rs886424 in
LINC00243 gene and
Bipolar Disorder
PMID 22688191 2012 Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.
rs324899 in
LINC00461 gene and
Bipolar Disorder
PMID 29121268 2018 Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
rs885553 in
LINC01121 gene and
Bipolar Disorder
PMID 25781172 2015 Infection and inflammation in schizophrenia and bipolar disorder: a genome wide study for interactions with genetic variation.
rs12144699 in
LINC01358;HSD52 gene and
Bipolar Disorder
PMID 26503763 2016 Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.
rs2635253 in
LINC01378 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs12153740 in
LINC01470 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs16935279 in
LINC01592 gene and
Bipolar Disorder
PMID 25944848 2015 Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs.
rs61580878 in
LINC01643 gene and
Bipolar Disorder
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
rs10889182 in
LINC01748 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
PMID 19416921 2009 Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.
rs111940429 in
LINC01789 gene and
Bipolar Disorder
PMID 29391396 2018 In the meta-analysis comparing cases with BD with comorbid BE vs. non-BD controls, a genome-wide significant association was observed at SNP rs111940429 in an intergenic region near PPP1R2P5 (p = 1.21E-08).
rs1532965 in
LINC02033 gene and
Bipolar Disorder
PMID 24618891 2014 Genome-wide association study reveals two new risk loci for bipolar disorder.
rs679895 in
LINC02109;LOC105374699 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs416350 in
LINC02384 gene and
Bipolar Disorder
PMID 22365631 2012 Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.
rs12898460 in
LINC02694 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
PMID 18711365 2008 Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.
PMID 20351715 2011 Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.
PMID 23070075 2013 Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.
rs12563333 in
LINC02779 gene and
Bipolar Disorder
PMID 22205951 2011 Genome-wide association study in bipolar patients stratified by co-morbidity.
rs75062117 in
LINC02822 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs10968749 in
LINGO2 gene and
Bipolar Disorder
PMID 25944848 2015 Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs.
rs2271893 in
LMAN2L gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
PMID 28072414 2017 Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder.
rs76082815 in
LMO7 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs17785382 in
LOC100507564;LRP8 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs12325410 in
LOC101927026 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs9862857 in
LOC101927995;LOC105377013 gene and
Bipolar Disorder
PMID 25944848 2015 Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs.
rs10745843 in
LOC101928937;ANKS1B gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs36030485 in
LOC101930053;LOC105375956 gene and
Bipolar Disorder
PMID 27890468 2017 Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis.
rs72977016 in
LOC102724068 gene and
Bipolar Disorder
PMID 24322204 2014 Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.
rs12300899 in
LOC105370052 gene and
Bipolar Disorder
PMID 24322204 2014 Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.
rs17541406 in
LOC105370982 gene and
Bipolar Disorder
PMID 24322204 2014 Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.
rs12149074 in
LOC105371357 gene and
Bipolar Disorder
PMID 26433762 2016 A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region.
rs7544145 in
LOC105371433 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs186197500 in
LOC105371630;RASAL2 gene and
Bipolar Disorder
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
rs2813164 in
LOC105371677 gene and
Bipolar Disorder
PMID 19416921 2009 Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.
rs12966547 in
LOC105372125 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs7240206 in
LOC105372213 gene and
Bipolar Disorder
PMID 26503763 2016 Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.
rs76087671 in
LOC105372577 gene and
Bipolar Disorder
PMID 29391396 2018 Bipolar disorder with binge eating behavior: a genome-wide association study implicates PRR5-ARHGAP8.
rs6090435 in
LOC105372725 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs4959270 in
LOC105374875 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs4947962 in
LOC105375284 gene and
Bipolar Disorder
PMID 26503763 2016 Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.
rs7004633 in
LOC105375630 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs62535709 in
LOC105376033;ZCCHC7 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs71420669 in
LOC105376755 gene and
Bipolar Disorder
PMID 27890468 2017 Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis.
rs11191454 in
LOC107984265;BORCS7-ASMT;AS3MT gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs9633553 in
LOC107984292;ANK3 gene and
Bipolar Disorder
PMID 24618891 2014 Genome-wide association study reveals two new risk loci for bipolar disorder.
rs10858583 in
LOC107984478 gene and
Bipolar Disorder
PMID 26433762 2016 A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region.
rs11829119 in
LOC107984527 gene and
Bipolar Disorder
PMID 25944848 2015 Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs.
rs115777110 in
LOC107985255 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs17662626 in
LOC107985969 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs72874541 in
LOC107986043 gene and
Bipolar Disorder
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
rs2205829 in
LOC107986584 gene and
Bipolar Disorder
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
rs115769866 in
LOC107986586 gene and
Bipolar Disorder
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
rs16923209 in
LOC107986945 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs2571521 in
LOC107987027 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs57646126 in
LTN1 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs11231677 in
MACROD1 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs6079468 in
MACROD2 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs10275045 in
MAD1L1 gene and
Bipolar Disorder
PMID 24280982 2014 Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
PMID 27329760 2016 Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.
PMID 24166486 2013 GWAS meta analysis identifies TSNARE1 as a novel Schizophrenia / Bipolar susceptibility locus.
rs2011503 in
MAU2 gene and
Bipolar Disorder
PMID 24618891 2014 Genome-wide association study reveals two new risk loci for bipolar disorder.
rs17418283 in
MCTP1 gene and
Bipolar Disorder
PMID 19416921 2009 Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.
rs12618769 in
MGAT4A gene and
Bipolar Disorder
PMID 21738484 2011 Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes.
rs1625579 in
MIR137HG gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs1511237 in
MIR708;TENM4 gene and
Bipolar Disorder
PMID 24618891 2014 Genome-wide association study reveals two new risk loci for bipolar disorder.
rs114034759 in
MKLN1 gene and
Bipolar Disorder
PMID 27769005 2017 A genome wide association study suggests the association of muskelin with early onset bipolar disorder: Implications for a GABAergic epileptogenic neurogenesis model.
rs182107583 in
MMADHC-DT gene and
Bipolar Disorder
PMID 29391396 2018 Bipolar disorder with binge eating behavior: a genome-wide association study implicates PRR5-ARHGAP8.
rs2721800 in
MPP6 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs74446114 in
MRPL33;RBKS gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs2302045 in
MTERF4;SNED1 gene and
Bipolar Disorder
PMID 25944848 2015 Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs.
rs3132581 in
MUCL3;HCG21;SFTA2 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs7959663 in
MYO1H gene and
Bipolar Disorder
PMID 29121268 2018 Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
rs4939921 in
MYO5B gene and
Bipolar Disorder
PMID 18317468 2008 Whole-genome association study of bipolar disorder.
rs2956395 in
MYRF-AS1;MYRF gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs1064395 in
NCAN gene and
Bipolar Disorder
PMID 21353194 2011 Our results provide evidence that rs1064395 is a common risk factor for BD.
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs12497998 in
NEK4 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs1927252 in
NEK7 gene and
Bipolar Disorder
PMID 21738484 2011 Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes.
rs1125777 in
NFIA gene and
Bipolar Disorder
PMID 22925353 2013 A genome-wide association study of seasonal pattern mania identifies NF1A as a possible susceptibility gene for bipolar disorder.
rs4926298 in
NFIX gene and
Bipolar Disorder
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
rs10489167 in
NFYC gene and
Bipolar Disorder
PMID 26297903 2016 Genetics of long-term treatment outcome in bipolar disorder.
rs34096808 in
NLGN1 gene and
Bipolar Disorder
PMID 27890468 2017 Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis.
rs17673138 in
NRG1 gene and
Bipolar Disorder
PMID 25944848 2015 Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs.
rs11191580 in
NT5C2 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs2333194 in
NUMB gene and
Bipolar Disorder
PMID 23092984 2012 These associations were present in all three samples, and both rs1171113 and rs2333194 were found to be overrepresented in an analysis of MICP cases compared with all other BP cases.
rs76371172 in
OTUD7A;LOC105370753 gene and
Bipolar Disorder
PMID 31164008 2019 GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.
rs10896090 in
PACS1 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs420259 in
PALB2 gene and
Bipolar Disorder
PMID 17554300 2007 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
PMID 21254220 2011 Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder.
rs57957974 in
PARP10 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs11720243 in
PBRM1 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
PMID 23070075 2013 Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.
rs10865974 in
PBRM1;GNL3 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs11714565 in
PBRM1;SMIM4 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs7122539 in
PC gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs11004733 in
PCDH15 gene and
Bipolar Disorder
PMID 31164008 2019 GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.
rs1039002 in
PDE10A gene and
Bipolar Disorder
PMID 22205951 2011 Bipolar disorder with psychosis and/or substance abuse in the absence of alcohol dependence was associated with the rare variant rs1039002 in the vicinity of the gene phosphodiesterase 10A (PDE10A) on chromosome 6q27 (p = 1.7×10⁻⁸).
rs66752127 in
PDE3B gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs13094687 in
PHF7 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs4356203 in
PIK3C2A gene and
Bipolar Disorder
PMID 24280982 2014 Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.
rs2299682 in
PLCB4 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs146727601 in
PLET1;PTS gene and
Bipolar Disorder
PMID 26503763 2016 Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.
rs113994095 in
POLG;MIR6766 gene and
Bipolar Disorder
PMID 23430834 2011 Stroke and Stroke-Like Symptoms in Patients with Mutations in the POLG1 Gene.
PMID 21686371 2009 Reversible valproate hepatotoxicity due to mutations in mitochondrial DNA polymerase γ (POLG1).
PMID 20691285 2011 POLG exon 22 skipping induced by different mechanisms in two unrelated cases of Alpers syndrome.
PMID 22342071 2012 Polymerase gamma deficiency (POLG): clinical course in a child with a two stage evolution from infantile myocerebrohepatopathy spectrum to an Alpers syndrome and neuropathological findings of Leigh's encephalopathy.
PMID 23212759 2013 POLG mutation presenting with late-onset jerky torticollis.
PMID 22189570 2012 Sensory neuronopathy in patients harbouring recessive polymerase γ mutations.
PMID 24725338 2014 Valproic acid triggers increased mitochondrial biogenesis in POLG-deficient fibroblasts.
PMID 22616202 2011 Sensory ataxic neuropathy with dysarthria/dysphagia and ophthalmoplegia (SANDO). Two case reports.
PMID 22931735 2012 Early-onset ataxia with progressive external ophthalmoplegia associated with POLG mutation: autosomal recessive mitochondrial ataxic syndrome or SANDO?
PMID 26735972 2016 A Clinical, Neuropathological and Genetic Study of Homozygous A467T POLG-Related Mitochondrial Disease.
PMID 28771251 2018 Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test.
PMID 22995991 2013 An informatics approach to analyzing the incidentalome.
PMID 22006280 2011 Bowel obstruction in patients with Alpers-Huttenlocher syndrome.
PMID 23448099 2013 Prospective study of POLG mutations presenting in children with intractable epilepsy: prevalence and clinical features.
PMID 29588995 2018 The adjunctive application of transcranial direct current stimulation in the management of de novo refractory epilepsia partialis continua in adolescent-onset POLG-related mitochondrial disease.
PMID 27987238 2017 Enrichment of deleterious variants of mitochondrial DNA polymerase gene (POLG1) in bipolar disorder.
PMID 25286830 2014 Cranial nerve and cervical root enhancement in an infant with polymerase gamma mutation mitochondrial disease.
PMID 21993618 2012 Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE)-like phenotype: an expanded clinical spectrum of POLG1 mutations.
PMID 23783014 2013 Reduced mitochondrial DNA content and heterozygous nuclear gene mutations in patients with acute liver failure.
PMID 24272679 2014 Abnormalities in glycogen metabolism in a patient with alpers' syndrome presenting with hypoglycemia.
PMID 26104464 2016 The spectrum of epilepsy caused by POLG mutations.
PMID 20837861 2010 POLG1 variations presenting as multiple sclerosis.
PMID 18783964 2009 Proof of progression over time: finally fulminant brain, muscle, and liver affection in Alpers syndrome associated with the A467T POLG1 mutation.
PMID 21647632 2012 MELAS/SANDO overlap syndrome associated with POLG1 mutations.
PMID 18500570 2008 Normal biochemical analysis of the oxidative phosphorylation (OXPHOS) system in a child with POLG mutations: a cautionary note.
PMID 18546343 2008 Apraxia of lid opening mimicking ptosis in compound heterozygosity for A467T and W748S POLG1 mutations.
PMID 16368709 2006 Mitochondrial and nuclear DNA defects in Saccharomyces cerevisiae with mutations in DNA polymerase gamma associated with progressive external ophthalmoplegia.
PMID 19538466 2011 Mitochondrial DNA depletion and fatal infantile hepatic failure due to mutations in the mitochondrial polymerase γ (POLG) gene: a combined morphological/enzyme histochemical and immunocytochemical/biochemical and molecular genetic study.
PMID 21235791 2011 Molecular and biochemical characterisation of a novel mutation in POLG associated with Alpers syndrome.
PMID 19766516 2010 Cerebral folate deficiency and CNS inflammatory markers in Alpers disease.
PMID 20818383 2010 High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency.
PMID 19813183 2010 Sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO) in a sibling pair with a homozygous p.A467T POLG mutation.
PMID 15824347 2005 Autosomal recessive mitochondrial ataxic syndrome due to mitochondrial polymerase gamma mutations.
PMID 16024923 2005 The common A467T mutation in the human mitochondrial DNA polymerase (POLG) compromises catalytic efficiency and interaction with the accessory subunit.
PMID 20576279 2010 [Mitochondrial DNA depletion and POLG mutations in a patient with sensory ataxia, dysarthria and ophthalmoplegia].
PMID 19501198 2009 De novo mutation in POLG leads to haplotype insufficiency and Alpers syndrome.
PMID 21515089 2011 Parieto-occipital lobe epilepsy caused by a POLG1 compound heterozygous A467T/W748S genotype.
PMID 20138553 2010 POLG DNA testing as an emerging standard of care before instituting valproic acid therapy for pediatric seizure disorders.
PMID 15917273 2005 Functional defects due to spacer-region mutations of human mitochondrial DNA polymerase in a family with an ataxia-myopathy syndrome.
PMID 11431686 2001 Mutation of POLG is associated with progressive external ophthalmoplegia characterized by mtDNA deletions.
PMID 15122711 2004 POLG mutations associated with Alpers' syndrome and mitochondrial DNA depletion.
rs7618915 in
PPM1M gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs17387100 in
PROM1 gene and
Bipolar Disorder
PMID 24964207 2014 Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study.
rs1171113 in
PRSS35 gene and
Bipolar Disorder
PMID 23092984 2012 These associations were present in all three samples, and both rs1171113 and rs2333194 were found to be overrepresented in an analysis of MICP cases compared with all other BP cases.
rs13061878 in
PTPRG gene and
Bipolar Disorder
PMID 27890468 2017 Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis.
rs17173608 in
RARRES2 gene and
Bipolar Disorder
PMID 24964207 2014 Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study.
rs17211233 in
RASGRF2 gene and
Bipolar Disorder
PMID 30552317 2018 Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression.
rs2287921 in
RASIP1 gene and
Bipolar Disorder
PMID 23070075 2013 Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.
rs4377455 in
RBMS3 gene and
Bipolar Disorder
PMID 20451256 2010 A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample.
rs2252865 in
RERE gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs17790731 in
RFESD gene and
Bipolar Disorder
PMID 25944848 2015 Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs.
rs2463709 in
RIMS1 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs1359582 in
RNLS gene and
Bipolar Disorder
PMID 26297903 2016 Genetics of long-term treatment outcome in bipolar disorder.
rs74417947 in
RPN2 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs16836940 in
RPRD2 gene and
Bipolar Disorder
PMID 30626913 2019 Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression.
rs10455979 in
RPS6KA2 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs10489744 in
RXRG gene and
Bipolar Disorder
PMID 27890468 2017 Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis.
rs17183814 in
SCN2A gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs6703335 in
SDCCAG8 gene and
Bipolar Disorder
PMID 24166486 2013 GWAS meta analysis identifies TSNARE1 as a novel Schizophrenia / Bipolar susceptibility locus.
rs55945116 in
SEC11A gene and
Bipolar Disorder
PMID 30552317 2018 Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression.
rs116323614 in
SESTD1 gene and
Bipolar Disorder
PMID 26503763 2016 Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.
rs12575685 in
SHANK2 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs138321 in
SLC25A17 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs145763646 in
SLC25A26 gene and
Bipolar Disorder
PMID 29391396 2018 Bipolar disorder with binge eating behavior: a genome-wide association study implicates PRR5-ARHGAP8.
rs10134944 in
SLC35F4 gene and
Bipolar Disorder
PMID 21254220 2011 Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder.
rs56037433 in
SLC4A10 gene and
Bipolar Disorder
PMID 27890468 2017 Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis.
rs138449918 in
SLC8A1-AS1 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs35425515 in
SLIT1 gene and
Bipolar Disorder
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
rs2251219 in
SMIM4;PBRM1 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs9362426 in
SMIM8 gene and
Bipolar Disorder
PMID 26297903 2016 Genetics of long-term treatment outcome in bipolar disorder.
rs13086738 in
SOX2-OT gene and
Bipolar Disorder
PMID 26433762 2016 A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region.
rs6954854 in
SP4 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs12635140 in
SPCS1;GLT8D1 gene and
Bipolar Disorder
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs312262717 in
SPG11 gene and
Bipolar Disorder
PMID 19194956 2009 SPG11 mutations cause Kjellin syndrome, a hereditary spastic paraplegia with thin corpus callosum and central retinal degeneration.
rs7872515 in
SPTLC1 gene and
Bipolar Disorder
PMID 22688191 2012 Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.
rs10035291 in
SSBP2 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs4447398 in
STARD9 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs137928907 in
STX2 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs1203233 in
SYNE1 gene and
Bipolar Disorder
PMID 28072414 2017 Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder.
PMID 20351715 2011 Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
PMID 21926972 2011 Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
PMID 23070075 2013 Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs7089973 in
TAF9BP2;ABLIM1 gene and
Bipolar Disorder
PMID 27890468 2017 Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis.
rs77866734 in
TCF3 gene and
Bipolar Disorder
PMID 26503763 2016 Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.
rs11152369 in
TCF4 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs12772424 in
TCF7L2 gene and
Bipolar Disorder
PMID 24322204 2014 Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.
rs28625169 in
TENM3 gene and
Bipolar Disorder
PMID 26806518 2016 Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.
rs10501439 in
TENM4 gene and
Bipolar Disorder
PMID 24618891 2014 Genome-wide association study reveals two new risk loci for bipolar disorder.
PMID 21926972 2011 Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
PMID 23070075 2013 Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs113779084 in
THSD7A gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs72966520 in
TLCD4-RWDD3;TLCD4 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs914715 in
TLE4 gene and
Bipolar Disorder
PMID 21254220 2011 Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder.
rs7296262 in
TMEM132C gene and
Bipolar Disorder
PMID 21423239 2012 A genome-wide association study of attempted suicide.
rs7939917 in
TMPRSS5 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs6568686 in
TRAF3IP2-AS1 gene and
Bipolar Disorder
PMID 26297903 2016 Genetics of long-term treatment outcome in bipolar disorder.
rs11129735 in
TRANK1 gene and
Bipolar Disorder
PMID 24618891 2014 Genome-wide association study reveals two new risk loci for bipolar disorder.
PMID 22182935 2013 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.
rs2021722 in
TRIM26 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs79436609 in
TRIM42 gene and
Bipolar Disorder
PMID 24322204 2014 Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.
rs3818253 in
TRPC4AP gene and
Bipolar Disorder
PMID 23070075 2013 Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.
rs116403057 in
TSBP1-AS1;TSBP1 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs1705236 in
TSPAN8 gene and
Bipolar Disorder
PMID 18317468 2008 Whole-genome association study of bipolar disorder.
rs7219021 in
TTLL6 gene and
Bipolar Disorder
PMID 24280982 2014 Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.
rs6738485 in
UXS1 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs149268645 in
WDR12;CARF gene and
Bipolar Disorder
PMID 31164008 2019 GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.
rs139459337 in
ZBTB20 gene and
Bipolar Disorder
PMID 30217971 2018 Genome-wide association study of seasonal affective disorder.
rs11557713 in
ZCCHC2 gene and
Bipolar Disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs9297357 in
ZFPM2;LOC105375695 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs9393813 in
ZNF204P gene and
Bipolar Disorder
PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
rs62110082 in
ZNF577 gene and
Bipolar Disorder
PMID 24322204 2014 Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.
rs1715 in
ZNF615 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
rs74796725 in
ZNF740 gene and
Bipolar Disorder
PMID 29064472 2017 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
rs62200793 in
ZNF804A gene and
Bipolar Disorder
PMID 29121268 2018 Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
rs10405744 in
ZNF93 gene and
Bipolar Disorder
PMID 25944848 2015 Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs.
rs8321 in
ZNRD1 gene and
Bipolar Disorder
PMID 23453885 2013 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.