Gene: BIN3

Alternate names for this Gene: -

Gene Summary: The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.

Gene is located in Chromosome: 8

Location in Chromosome : 8p21.3

Description of this Gene: bridging integrator 3

Type of Gene: protein-coding

rs4872526 in BIN3 gene and Glomerular Filtration Rate PMID 31152163 2019 A catalog of genetic loci associated with kidney function from analyses of a million individuals.

rs6558172 in BIN3 gene and High density lipoprotein measurement PMID 30275891 2018 Family-based genome-wide association of inflammation biomarkers and fenofibrate treatment response in the GOLDN study.

rs2280104 in BIN3 gene and Parkinson Disease PMID 28892059 2017 A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.

rs6558172 in BIN3 gene and Triglycerides measurement PMID 30275891 2018 Family-based genome-wide association of inflammation biomarkers and fenofibrate treatment response in the GOLDN study.