Gene: C8orf44-SGK3

Alternate names for this Gene: -

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring putative uncharacterized protein C8orf44 (GeneID 56260) and serine/threonine-protein kinase Sgk3 (GeneID 23678) genes on chromosome 8. The read-through transcript produces a protein that shares sequence identity with the downstream gene product.

Gene is located in Chromosome: 8

Location in Chromosome : 8q13.1

Description of this Gene: C8orf44-SGK3 readthrough

Type of Gene: protein-coding

Gene: SGK3

Alternate names for this Gene: CISK|SGK2|SGKL

Gene Summary: This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene is located in Chromosome: 8

Location in Chromosome : 8q13.1

Description of this Gene: serum/glucocorticoid regulated kinase family member 3

Type of Gene: protein-coding

rs191342285 in C8orf44-SGK3;SGK3 gene and Alzheimer's Disease PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.