Condition: Alzheimer's Disease
rs2740488 in
ABCA1 gene and
Alzheimer's Disease
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs115550680 in
ABCA7 gene and
Alzheimer's Disease
PMID 23571587 2013 Genome-wide significance in fully adjusted models (sex, age, APOE genotype, population stratification) was observed for a SNP in ABCA7 (rs115550680, allele = G; frequency, 0.09 cases and 0.06 controls; odds ratio [OR], 1.79 [95% CI, 1.47-2.12]; P = 2.2 × 10(-9)), which is in linkage disequilibrium with SNPs previously associated with Alzheimer disease in Europeans (0.8 < D' < 0.9).
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 21460840 2011 Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
rs3795065 in
ABCA7;CNN2 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs16973424 in
ABCA8 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs7576531 in
ABCB11 gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs4311 in
ACE gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs476428 in
ACSL6 gene and
Alzheimer's Disease
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
rs442495 in
ADAM10 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs4575098 in
ADAMTS4;B4GALT3 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs10948374 in
ADGRF2 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs340635 in
AFF1 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs62013859 in
AGBL1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs2734897 in
AGFG2 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs11588387 in
AHCYL1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs141218484 in
AHNAK gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs3794318 in
AICDA gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs149454736 in
AKAP9 gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs12148780 in
ALDH1A2 gene and
Alzheimer's Disease
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs111816999 in
ALOX12-AS1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs76726049 in
ALPK2 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs4704171 in
ANKRD31 gene and
Alzheimer's Disease
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
rs4700060 in
ANKRD55 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs117556552 in
ANO3 gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs1399439 in
ANO4 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs10751667 in
AP2A2 gene and
Alzheimer's Disease
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
rs2293479 in
AP4M1 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs117618017 in
APH1B gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs2678379 in
APOB gene and
Alzheimer's Disease
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs3925681 in
APOC1 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30636644 2019 Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
PMID 22832961 2012 Genome-wide association study of Alzheimer's disease.
PMID 17998437 2008 Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
PMID 19734903 2009 Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 22005931 2012 Genome-wide association analysis of age-at-onset in Alzheimer's disease.
PMID 17975299 2008 Sorl1 as an Alzheimer's disease predisposition gene?
PMID 17474819 2007 A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.
PMID 28183528 2017 Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
PMID 23419831 2014 APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.
rs5112 in
APOC1P1 gene and
Alzheimer's Disease
PMID 19734903 2009 Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs9304644 in
APOC2;APOC4-APOC2 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs12721109 in
APOC4;APOC4-APOC2 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs1081105 in
APOE gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 19136949 2009 Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease.
PMID 22832961 2012 Genome-wide association study of Alzheimer's disease.
PMID 24755620 2014 Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.
PMID 19734903 2009 Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
PMID 30636644 2019 Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.
PMID 22005930 2012 Genome-wide association study of Alzheimer's disease with psychotic symptoms.
PMID 21379329 2011 Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 20885792 2010 Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.
PMID 25027320 2014 SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.
PMID 21123754 2011 Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
PMID 31055733 2019 Genetic heterogeneity of Alzheimer's disease in subjects with and without hypertension.
PMID 23419831 2014 APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.
PMID 23565137 2013 SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
PMID 23562540 2013 GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
rs281865161 in
APP gene and
Alzheimer's Disease
PMID 23649480 2013 Swedish mutant APP suppresses osteoblast differentiation and causes osteoporotic deficit, which are ameliorated by N-acetyl-L-cysteine.
PMID 21335619 2011 Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation.
PMID 8810256 1996 Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice.
PMID 27858710 2017 APP Mutations in Cerebral Amyloid Angiopathy with or without Cortical Calcifications: Report of Three Families and a Literature Review.
PMID 28350801 2017 APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases.
PMID 27000221 2016 Iowa APP mutation-related hereditary cerebral amyloid angiopathy (CAA): A new family from Spain.
PMID 11441013 2001 Pathogenic effects of D23N Iowa mutant amyloid beta -protein.
PMID 26402770 2015 Modeling the Aggregation Propensity and Toxicity of Amyloid-β Variants.
PMID 24878480 2014 Familial cerebral amyloid angiopathy due to the Iowa mutation in an Irish family.
PMID 26104569 2015 Iowa-type hereditary cerebral amyloid angiopathy in a Polish family.
PMID 20228223 2010 Iowa variant of familial Alzheimer's disease: accumulation of posttranslationally modified AbetaD23N in parenchymal and cerebrovascular amyloid deposits.
PMID 10656250 1999 Identification of a novel aspartic protease (Asp 2) as beta-secretase.
PMID 10677483 2000 Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein.
PMID 1678058 1991 Mis-sense mutation Val----Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease.
PMID 1415269 1992 Linkage and mutational analysis of familial Alzheimer disease kindreds for the APP gene region.
PMID 1671712 1991 Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease.
PMID 11063718 2000 Nonfibrillar diffuse amyloid deposition due to a gamma(42)-secretase site mutation points to an essential role for N-truncated A beta(42) in Alzheimer's disease.
PMID 10867787 2000 Early-onset Alzheimer disease caused by a new mutation (V717L) in the amyloid precursor protein gene.
PMID 11311152 2001 In vitro studies of amyloid beta-protein fibril assembly and toxicity provide clues to the aetiology of Flemish variant (Ala692-->Gly) Alzheimer's disease.
PMID 1303275 1992 More missense in amyloid gene.
PMID 1465129 1992 Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production.
PMID 9754958 1998 Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692Ala-->Gly mutation.
PMID 9328472 1997 A new pathogenic mutation in the APP gene (I716V) increases the relative proportion of A beta 42(43).
PMID 15365148 2004 A family with Alzheimer disease and strokes associated with A713T mutation of the APP gene.
PMID 12034808 2002 An Iranian family with Alzheimer's disease caused by a novel APP mutation (Thr714Ala).
PMID 8577393 1995 A mutation in codon 717 of the amyloid precursor protein gene in an Australian family with Alzheimer's disease.
PMID 15201367 2004 Novel amyloid precursor protein gene missense mutation (D678N) in probable familial Alzheimer's disease.
PMID 1302033 1992 A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid.
PMID 11528419 2001 The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation.
PMID 8267572 1993 Characterization of amyloid fibril beta-peptide in familial Alzheimer's disease with APP717 mutations.
PMID 1303239 1992 Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene.
PMID 15201367 2004 The production and accumulation of mutated Abeta (Asn7-Abeta) or the misfunction of D678N mutant APP may have pathogenic properties for the development of Alzheimer's disease in this pedigree.
PMID 15365148 2004 This indicates that the A713T mutation of the APP gene, lying at the gamma-secretase cleavage site, can be responsible for AD with symptomatic cerebral amyloid angiopathy.
PMID 24829003 2014 Fourth Canadian Consensus Conference on the Diagnosis and Treatment of Dementia: recommendations for family physicians.
PMID 20831773 2010 EFNS guidelines for the diagnosis and management of Alzheimer's disease.
PMID 21500874 2010 Preventing Alzheimer's disease and cognitive decline.
PMID 19281847 2009 Mutations in amyloid precursor protein affect its interactions with presenilin/gamma-secretase.
PMID 15776278 2005 Novel mutations and repeated findings of mutations in familial Alzheimer disease.
PMID 1925564 1991 A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease.
PMID 25138979 2014 Early-onset Alzheimer's disease in two Iranian families: a genetic study.
PMID 11978821 2002 Although these data open perspectives for therapy of AD by gamma-secretase inhibition, the neuronal absence of PS1 failed to rescue the cognitive defect, assessed by the object recognition test, of the parent APP[V717I] transgenic mice.
PMID 7806491 1994 APP717 missense mutation affects the ratio of amyloid beta protein species (A beta 1-42/43 and a beta 1-40) in familial Alzheimer's disease brain.
PMID 24650794 2014 Mutational analysis in early-onset familial Alzheimer's disease in Mainland China.
PMID 27838006 2017 Clinical characterization of an APP mutation (V717I) in five Han Chinese families with early-onset Alzheimer's disease.
PMID 24524897 2014 The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons.
PMID 12034808 2002 An Iranian family with Alzheimer's disease caused by a novel APP mutation (Thr714Ala).
rs116105213 in
ARAP2 gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs326946 in
ARHGAP20 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs2732703 in
ARL17B gene and
Alzheimer's Disease
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
rs144191434 in
ARVCF;TANGO2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs11983798 in
ATXN7L1 gene and
Alzheimer's Disease
PMID 22881374 2012 Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene.
rs6468852 in
AZIN1-AS1 gene and
Alzheimer's Disease
PMID 22881374 2012 Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene.
rs116677506 in
B3GALT1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs1135062 in
BCAM gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 22832961 2012 Genome-wide association study of Alzheimer's disease.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
rs72832584 in
BCAS3 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs889555 in
BCKDK gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs10401176 in
BCL3 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 19734903 2009 Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
PMID 24755620 2014 Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.
PMID 22832961 2012 Genome-wide association study of Alzheimer's disease.
rs76320948 in
BHMG1 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs10194375 in
BIN1 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 22005930 2012 Genome-wide association study of Alzheimer's disease with psychotic symptoms.
rs111243475 in
BLOC1S3;MARK4 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs17169634 in
BMPER gene and
Alzheimer's Disease
PMID 24770881 2014 ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
rs58370486 in
BZW2 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs117850870 in
C10orf71 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs181319480 in
C3orf67 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs191342285 in
C8orf44-SGK3;SGK3 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs117964204 in
CACNA1G gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs12706411 in
CADPS2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs6014724 in
CASS4 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
rs858502 in
CASTOR3 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs112450640 in
CBLC gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs7364180 in
CCDC134 gene and
Alzheimer's Disease
PMID 21123754 2011 Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.
rs11821654 in
CCDC83 gene and
Alzheimer's Disease
PMID 22832961 2012 Genome-wide association study of Alzheimer's disease.
rs117983694 in
CCDC89 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs6808835 in
CCRL2;CCR5AS gene and
Alzheimer's Disease
PMID 25340798 2014 Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.
rs10948363 in
CD2AP gene and
Alzheimer's Disease
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
rs3865444 in
CD33 gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs382216 in
CDC42SE2 gene and
Alzheimer's Disease
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
rs77894924 in
CDH13 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs62400067 in
CDKAL1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs2965163 in
CEACAM16;LOC107985305 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs142034848 in
CEACAM19;LOC107985305 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs80257887 in
CEACAM20 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs11083742 in
CEACAM22P gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs10838725 in
CELF1 gene and
Alzheimer's Disease
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
rs201099 in
CELF2 gene and
Alzheimer's Disease
PMID 21379329 2011 Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
rs56357845 in
CHN2-AS1;CHN2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs2741342 in
CHRNA2 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs112481437 in
CLASRP gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs9302457 in
CLEC16A gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
rs115102486 in
CLMN gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs11672748 in
CLPTM1 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs11136000 in
CLU gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 19734903 2009 Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
PMID 19734902 2009 These associations were replicated in stage 2 (2,023 cases and 2,340 controls), producing compelling evidence for association with Alzheimer's disease in the combined dataset (rs11136000, P = 8.5 x 10(-10), odds ratio = 0.86; rs3851179, P = 1.3 x 10(-9), odds ratio = 0.86).
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs9331888 in
CLU;MIR6843 gene and
Alzheimer's Disease
PMID 19734903 2009 Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
rs111278892 in
CNN2;ABCA7 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs114360492 in
CNTNAP2 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
PMID 26049409 2015 A genome-wide association study of late-onset Alzheimer's disease in a Japanese population.
rs36099249 in
COL12A1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs79985863 in
COL18A1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs59904869 in
COL4A4 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs137929838 in
COLGALT2 gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs12036785 in
CR1 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 19734903 2009 Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
PMID 21460840 2011 Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
rs11118328 in
CR1L gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs61144803 in
CRADD gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs2046197 in
CSMD1 gene and
Alzheimer's Disease
PMID 30514930 2018 Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs6738962 in
CTNNA2 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs1861525 in
CYCS gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs2228467 in
CYP8B1;KRBOX1;ACKR2 gene and
Alzheimer's Disease
PMID 25340798 2014 Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.
rs79480822 in
DCAF7 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs12500118 in
DCHS2 gene and
Alzheimer's Disease
PMID 22005931 2012 Genome-wide association analysis of age-at-onset in Alzheimer's disease.
rs11220271 in
DDX25 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs75290158 in
DLX5 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs116348108 in
DMXL1 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs139934868 in
DSCAML1 gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs8093731 in
DSG2 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs185968827 in
DST;DST-AS1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs1975804 in
EIF3E;LOC105375704 gene and
Alzheimer's Disease
PMID 21379329 2011 Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
rs2392492 in
ELMO1 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs2718058 in
EPDR1;GPR141 gene and
Alzheimer's Disease
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs10808026 in
EPHA1 gene and
Alzheimer's Disease
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs11763230 in
EPHA1-AS1 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
rs3935067 in
EPHA1;EPHA1-AS1 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs2269461 in
EPHX2 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs4732728 in
EPHX2;GULOP gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs346757 in
EXOC3L2;MARK4 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 24755620 2014 Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.
rs11770757 in
EXOC4 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs17062407 in
EYA4 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs6927354 in
F13A1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
PMID 21116278 2011 Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.
rs117161928 in
FAM181A;FAM181A-AS1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs6491411 in
FARP1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs75002042 in
FBXL7 gene and
Alzheimer's Disease
PMID 26339675 2015 F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease.
rs17125944 in
FERMT2 gene and
Alzheimer's Disease
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
rs17125924 in
FERMT2;LOC105370500 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs11742761 in
FGF10 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs12091371 in
FMN2 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs758324 in
FNIP1 gene and
Alzheimer's Disease
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
rs17314229 in
FRMD4A gene and
Alzheimer's Disease
PMID 22430674 2013 Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease.
rs186127414 in
G3BP1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs1007837 in
GAB2 gene and
Alzheimer's Disease
PMID 17553421 2007 GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
rs901104 in
GAB2;USP35 gene and
Alzheimer's Disease
PMID 17553421 2007 GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
rs147028191 in
GABRA2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs74006954 in
GABRG3 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs78620885 in
GEMIN7-AS1;MARK4;GEMIN7 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs183321458 in
GEMIN7-AS1;ZNF296;GEMIN7 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs7251911 in
GEMIN7;GEMIN7-AS1 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs8100183 in
GEMIN7;MARK4;GEMIN7-AS1 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs60239918 in
GEMIN7;ZNF296;GEMIN7-AS1 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs117969561 in
GGACT gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs514716 in
GLIS3 gene and
Alzheimer's Disease
PMID 23562540 2013 We performed the largest genome-wide association study for cerebrospinal fluid (CSF) tau/ptau levels published to date (n = 1,269), identifying three genome-wide significant loci for CSF tau and ptau: rs9877502 (p = 4.89 × 10⁻⁹ for tau) located at 3q28 between GEMC1 and OSTN, rs514716 (p = 1.07 × 10⁻⁸ and p = 3.22 × 10⁻⁹ for tau and ptau, respectively), located at 9p24.2 within GLIS3 and rs6922617 (p = 3.58 × 10⁻⁸ for CSF ptau) at 6p21.1 within the TREM gene cluster, a region recently reported to harbor rare variants that increase AD risk.
rs4955783 in
GOLIM4 gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs143258881 in
GPC6 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs140442947 in
GSK3B gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs17172199 in
HECW1 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs8033755 in
HERC2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs9269853 in
HLA-DRB1 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs139675748 in
HSD17B12 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs2445130 in
HSPG2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs11083743 in
IGSF23 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs539159088 in
IGSF23;LOC107985305 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs2243170 in
IL19 gene and
Alzheimer's Disease
PMID 25649651 2015 Genetic Determinants of Survival in Patientswith Alzheimer’s Disease.
rs78927322 in
IL34 gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs1800795 in
IL6-AS1;IL6;STEAP1B gene and
Alzheimer's Disease
PMID 26545630 2016 A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin.
rs61812598 in
IL6R gene and
Alzheimer's Disease
PMID 25340798 2014 Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.
rs190500289 in
INHCAP;TF gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs10933431 in
INPP5D gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
rs191603973 in
INSIG1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs17488073 in
IRF2 gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs75009721 in
ITSN2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs59735493 in
KAT8 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs72639058 in
KAZN gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs4705644 in
KCNN2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs188911996 in
KDM1B gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs140996952 in
KHDRBS2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs62076840 in
L3MBTL4 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs183708309 in
LAMA1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs146168866 in
LAMP1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs2962508 in
LARS1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs79846291 in
LINC00271 gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs115694210 in
LINC00343 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs7047415 in
LINC00476 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs2298369 in
LINC00515 gene and
Alzheimer's Disease
PMID 30636644 2019 Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.
rs11768400 in
LINC00972 gene and
Alzheimer's Disease
PMID 19734903 2009 Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
rs146579248 in
LINC01184 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs115291397 in
LINC01185 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs6479525 in
LINC01508 gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs4907035 in
LINC01725 gene and
Alzheimer's Disease
PMID 21098978 2011 Identification of novel candidate genes for Alzheimer's disease by autozygosity mapping using genome wide SNP data.
PMID 20061627 2010 Genome-wide scan of copy number variation in late-onset Alzheimer's disease.
rs186971130 in
LINC01965 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs142710255 in
LINC02008 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs76930906 in
LINC02268 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs150511909 in
LINC02325 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs2588969 in
LINC02625 gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
rs73320584 in
LINC02653 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs115514216 in
LINC02699 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs11605427 in
LINC02705 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs35816125 in
LIPG gene and
Alzheimer's Disease
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs7225151 in
LOC100130950;SCIMP gene and
Alzheimer's Disease
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
rs139471609 in
LOC100506974;COX10-AS1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs1936246 in
LOC101927293 gene and
Alzheimer's Disease
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
rs73976310 in
LOC101928000;ZNF232 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs187370608 in
LOC101929555 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs137967137 in
LOC102724084 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs28394864 in
LOC102724596 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs1925458 in
LOC102724749;LOC105374976 gene and
Alzheimer's Disease
PMID 31055733 2019 Genetic heterogeneity of Alzheimer's disease in subjects with and without hypertension.
rs11610206 in
LOC105369746 gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 19118814 2009 Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease.
PMID 20885792 2010 Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.
rs79335261 in
LOC105369782;PA2G4;ERBB3 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs187293782 in
LOC105369844 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs185806653 in
LOC105370067 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs912322 in
LOC105370356;MYO16 gene and
Alzheimer's Disease
PMID 30636644 2019 Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.
rs1977412 in
LOC105373166 gene and
Alzheimer's Disease
PMID 30514930 2018 Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
rs11680911 in
LOC105373605 gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 22832961 2012 Genome-wide association study of Alzheimer's disease.
PMID 21390209 2011 Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
PMID 21627779 2011 The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.
rs75932628 in
LOC105375056;TREM2 gene and
Alzheimer's Disease
PMID 23150908 2013 A rare missense mutation (rs75932628-T) in the gene encoding the triggering receptor expressed on myeloid cells 2 (TREM2), which was predicted to result in an R47H substitution, was found to confer a significant risk of Alzheimer's disease in Iceland (odds ratio, 2.92; 95% confidence interval [CI], 2.09 to 4.09; P=3.42×10(-10)).
rs11773349 in
LOC105375328 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs62496419 in
LOC105375416 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs7920721 in
LOC105376412;LOC105376413 gene and
Alzheimer's Disease
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 28183528 2017 Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
rs11257238 in
LOC105376413;LOC105376412 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 28183528 2017 Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
rs211257 in
LOC105376485;LOC107984219 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs7374058 in
LOC105377002 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs61142792 in
LOC105377750;FAM193B gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs9372110 in
LOC105377923 gene and
Alzheimer's Disease
PMID 30514930 2018 Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
rs188951355 in
LOC105378208 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs61860854 in
LOC105378318 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs59616746 in
LOC105378387;SH2D4B gene and
Alzheimer's Disease
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
rs190780914 in
LOC105378392 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs11952762 in
LOC105379143 gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
rs56176358 in
LOC107984979 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs2795228 in
LOC107985037;LINC01712 gene and
Alzheimer's Disease
PMID 30514930 2018 Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
rs111740474 in
LOC107985305 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 22832961 2012 Genome-wide association study of Alzheimer's disease.
PMID 19734903 2009 Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
rs12150984 in
LOC107985305;CEACAM16 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs2919845 in
LOC107985305;CEACAM19 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs714948 in
LOC107985305;CEACAM19;PVR gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 24755620 2014 Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.
rs10426401 in
LOC107985305;PVR gene and
Alzheimer's Disease
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs2965156 in
LOC107985306;LOC107985305 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs150927461 in
LOC107985536 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs6448799 in
LOC107986178 gene and
Alzheimer's Disease
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs9381040 in
LOC107986595 gene and
Alzheimer's Disease
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
rs857551 in
LOC107987301 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs11154851 in
LOC644135;PDE7B gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs189794920 in
LOC652276 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs191975838 in
LOC730100 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs201825 in
LRAT gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
rs2043948 in
LTBP2 gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
rs12361953 in
LUZP2 gene and
Alzheimer's Disease
PMID 22881374 2012 Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene.
rs10501320 in
MADD;MADD-AS1 gene and
Alzheimer's Disease
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs2233083 in
MAPK7;MFAP4 gene and
Alzheimer's Disease
PMID 30636644 2019 Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.
rs10415983 in
MARK4;BLOC1S3 gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs10422797 in
MARK4;EXOC3L2 gene and
Alzheimer's Disease
PMID 21379329 2011 Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs28469095 in
MARK4;NKPD1;LOC105372420 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs10408847 in
MARK4;PPP1R37 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 23565137 2013 SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
rs11708767 in
MED12L gene and
Alzheimer's Disease
PMID 30514930 2018 Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
rs141568462 in
MEF2C-AS1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
rs143954261 in
MEGF10 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs142958719 in
MEIKIN gene and
Alzheimer's Disease
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
rs117250828 in
MICAL2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs243034 in
MIR4432HG gene and
Alzheimer's Disease
PMID 31055733 2019 Genetic heterogeneity of Alzheimer's disease in subjects with and without hypertension.
rs12808148 in
MMP12 gene and
Alzheimer's Disease
PMID 22832961 2012 Genome-wide association study of Alzheimer's disease.
rs2065108 in
MMP24-AS1-EDEM2;EDEM2 gene and
Alzheimer's Disease
PMID 18449908 2009 Genome screen of late-onset Alzheimer's extended pedigrees identifies TRPC4AP by haplotype analysis.
rs538867 in
MOBP gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs4145462 in
MPZL1 gene and
Alzheimer's Disease
PMID 22881374 2012 Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene.
rs474951 in
MS4A3 gene and
Alzheimer's Disease
PMID 24755620 2014 Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.
rs1026254 in
MS4A4A gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 21627779 2011 Meta-analysis of our data and independent replication datasets allowed us to confirm a novel genome-wide significant association of AD with the membrane-spanning 4-domains subfamily A (MS4A) gene cluster (rs1562990, P = 4.40E-11, odds ratio = 0.88, 95% confidence interval 0.85 to 0.91, n = 10,181 cases and 14,341 controls).
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs611267 in
MS4A4A;MS4A4E gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
rs11230201 in
MS4A4E;MS4A4A gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
rs12453 in
MS4A6A gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 21627779 2011 The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.
PMID 21460840 2011 Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs186552003 in
MSH2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs11754661 in
MTHFD1L gene and
Alzheimer's Disease
PMID 20885792 2010 Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.
rs150813880 in
MYO16 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs2409317 in
N6AMT1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs7588354 in
NCKAP5 gene and
Alzheimer's Disease
PMID 25649651 2015 Genetic Determinants of Survival in Patientswith Alzheimer’s Disease.
rs4836694 in
NCS1 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs249153 in
NDUFA12 gene and
Alzheimer's Disease
PMID 24755620 2014 Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.
rs10098778 in
NDUFAF6 gene and
Alzheimer's Disease
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
rs11665676 in
NECTIN2 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 21627779 2011 The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.
PMID 19734903 2009 Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 22832961 2012 Genome-wide association study of Alzheimer's disease.
PMID 23565137 2013 SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
PMID 20885792 2010 Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.
PMID 24755620 2014 Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.
PMID 28183528 2017 Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
PMID 30636644 2019 Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
PMID 22005930 2012 Genome-wide association study of Alzheimer's disease with psychotic symptoms.
PMID 21098978 2011 Identification of novel candidate genes for Alzheimer's disease by autozygosity mapping using genome wide SNP data.
PMID 22005931 2012 Genome-wide association analysis of age-at-onset in Alzheimer's disease.
PMID 23419831 2014 APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.
PMID 22159054 2011 A comprehensive genetic association study of Alzheimer disease in African Americans.
PMID 18823527 2008 A genome-wide association study for late-onset Alzheimer's disease using DNA pooling.
PMID 21379329 2011 Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
PMID 19136949 2009 Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease.
rs9749589 in
NFIC gene and
Alzheimer's Disease
PMID 28183528 2017 Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
rs2289506 in
NIT2 gene and
Alzheimer's Disease
PMID 30514930 2018 Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
rs117780815 in
NKAIN2 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs4557697 in
NKAIN3 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs10416371 in
NKPD1;LOC105372420;MARK4 gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 22832961 2012 Genome-wide association study of Alzheimer's disease.
rs10421247 in
NKPD1;MARK4;LOC105372420 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs3931397 in
NR3C2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs1347297 in
OSBPL6 gene and
Alzheimer's Disease
PMID 26830138 2016 Using a multivariate phenotype combining affection status and onset age, meta-analysis of the association results revealed three single nucleotide polymorphisms (SNPs) that achieved genome-wide significance for association with AD risk: rs7609954 in the gene PTPRG (P-value=3.98 × 10<sup>-8</sup>), rs1347297 in the gene OSBPL6 (P-value=4.53 × 10<sup>-8</sup>), and rs1513625 near PDCL3 (P-value=4.28 × 10<sup>-8</sup>).
rs183562580 in
OTOF gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs117154046 in
OVCH1-AS1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs13283845 in
PALM2AKAP2 gene and
Alzheimer's Disease
PMID 23565137 2013 SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
rs75617873 in
PARVB gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs2573905 in
PCDH11X gene and
Alzheimer's Disease
PMID 19136949 2009 Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
rs10975167 in
PDCD1LG2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs112724034 in
PGAM5P1;LINC01848 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs183600932 in
PHF14 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs10501602 in
PICALM gene and
Alzheimer's Disease
PMID 22832961 2012 Genome-wide association study of Alzheimer's disease.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs1859788 in
PILRA gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs118048115 in
PLPP4 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs277470 in
PLXNA4 gene and
Alzheimer's Disease
PMID 25043464 2014 PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation.
rs116139393 in
PMS2CL gene and
Alzheimer's Disease
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
rs139090762 in
PNPLA7 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs1048699 in
PPP1R37;MARK4 gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs3748140 in
PPP1R3B gene and
Alzheimer's Disease
PMID 22832961 2012 Genome-wide association study of Alzheimer's disease.
rs182838111 in
PPP1R42 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs2421847 in
PRRC2C gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs12292911 in
PSMC3 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs10109834 in
PTK2B gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
rs7609954 in
PTPRG gene and
Alzheimer's Disease
PMID 26830138 2016 Using a multivariate phenotype combining affection status and onset age, meta-analysis of the association results revealed three single nucleotide polymorphisms (SNPs) that achieved genome-wide significance for association with AD risk: rs7609954 in the gene PTPRG (P-value=3.98 × 10<sup>-8</sup>), rs1347297 in the gene OSBPL6 (P-value=4.53 × 10<sup>-8</sup>), and rs1513625 near PDCL3 (P-value=4.28 × 10<sup>-8</sup>).
rs203709 in
PVR;LOC107985305 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs148273964 in
RAB3D;TSPAN16 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs17034806 in
RANBP2 gene and
Alzheimer's Disease
PMID 20885792 2010 Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.
rs6890695 in
RAPGEF6 gene and
Alzheimer's Disease
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
rs75885813 in
RBFOX1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs112380717 in
RELB gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs80011616 in
RNF165 gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs62187521 in
RSPO4 gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs148763909 in
SAP30L gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs485902 in
SCARA3 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs78194510 in
SCARB1 gene and
Alzheimer's Disease
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs113260531 in
SCIMP;LOC100130950 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs145049847 in
SDR42E2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs72728723 in
SETD7 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs4896030 in
SGK1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs9994441 in
SH3RF1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs13164495 in
SIMC1 gene and
Alzheimer's Disease
PMID 21379329 2011 Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
rs7303876 in
SLC16A7 gene and
Alzheimer's Disease
PMID 20885792 2010 Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.
rs10498633 in
SLC24A4 gene and
Alzheimer's Disease
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs114090132 in
SLC25A48 gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs147845115 in
SLC4A8 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs75847378 in
SLC8A1-AS1 gene and
Alzheimer's Disease
PMID 24770881 2014 ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
rs149038799 in
SMILR gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs34804891 in
SNX9 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs117792039 in
SORCS3 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs11218343 in
SORL1 gene and
Alzheimer's Disease
PMID 23565137 2013 SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
rs4794202 in
SP6 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs9369477 in
SPATS1 gene and
Alzheimer's Disease
PMID 30514930 2018 Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
rs3740688 in
SPI1 gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs11023139 in
SPON1 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs8035452 in
SPPL2A gene and
Alzheimer's Disease
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
rs140661185 in
SPRED2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs72807343 in
SQSTM1 gene and
Alzheimer's Disease
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
rs7009219 in
ST18 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs3936289 in
ST6GAL1 gene and
Alzheimer's Disease
PMID 28560309 2017 Single-nucleotide polymorphisms are associated with cognitive decline at Alzheimer's disease conversion within mild cognitive impairment patients.
rs4727449 in
STAG3;CASTOR3 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs35305377 in
STAG3L5P;PMS2P1;STAG3L5P-PVRIG2P-PILRB gene and
Alzheimer's Disease
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
rs78647349 in
STK32B gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs34111070 in
STRADA gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs62256378 in
SUCLG2 gene and
Alzheimer's Disease
PMID 25027320 2014 Clinically, rs62256378 was associated with rate of cognitive decline in AD dementia patients (P = 3.1 × 10(-3)).
rs147991290 in
SYNJ1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs182798940 in
SZT2;HYI gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs71377714 in
TCAM1P gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs17747324 in
TCF7L2 gene and
Alzheimer's Disease
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs17072596 in
TENM3-AS1;TENM3 gene and
Alzheimer's Disease
PMID 17998437 2008 Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
rs117496069 in
TEX33 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs181424343 in
TGFB2 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs34972666 in
TGM6 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs142200609 in
THSD4 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs2456930 in
TLN2 gene and
Alzheimer's Disease
PMID 20197096 2010 Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.
rs118099348 in
TMC5 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs144288546 in
TMEM132C gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs8045064 in
TNRC6A;LINC01567 gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs10119 in
TOMM40 gene and
Alzheimer's Disease
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
PMID 22832961 2012 Genome-wide association study of Alzheimer's disease.
PMID 19734903 2009 Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
PMID 23565137 2013 SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
PMID 24770881 2014 ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 30636644 2019 Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.
PMID 29777097 2018 GWAS on family history of Alzheimer's disease.
PMID 21123754 2011 Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.
PMID 20885792 2010 Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.
PMID 19125160 2010 Examination of the current top candidate genes for AD in a genome-wide association study.
PMID 21627779 2011 The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.
PMID 24755620 2014 Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.
PMID 21379329 2011 Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
PMID 19136949 2009 Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease.
PMID 22005930 2012 Genome-wide association study of Alzheimer's disease with psychotic symptoms.
PMID 22005931 2012 Genome-wide association analysis of age-at-onset in Alzheimer's disease.
PMID 26993346 2016 Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease.
PMID 20460622 2010 Genome-wide analysis of genetic loci associated with Alzheimer disease.
PMID 20061627 2010 Genome-wide scan of copy number variation in late-onset Alzheimer's disease.
PMID 29107063 2018 Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses.
PMID 19734902 2009 Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
PMID 21098978 2011 Identification of novel candidate genes for Alzheimer's disease by autozygosity mapping using genome wide SNP data.
PMID 26339675 2015 F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease.
PMID 23419831 2014 APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs61960582 in
TPTE2P3;LINC00345 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs143332484 in
TREM2;LOC105375056 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs3850930 in
TRIM51CP gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs74615166 in
TRIP4 gene and
Alzheimer's Disease
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
rs56214552 in
TRIQK gene and
Alzheimer's Disease
PMID 29274321 2018 Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
rs1885119 in
TRPC4AP gene and
Alzheimer's Disease
PMID 18449908 2009 Genome screen of late-onset Alzheimer's extended pedigrees identifies TRPC4AP by haplotype analysis.
rs149916999 in
TRPM1 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs2632516 in
TSPOAP1-AS1;MIR142 gene and
Alzheimer's Disease
PMID 28183528 2017 Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs116886320 in
TULP4 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs5754166 in
UBE2L3 gene and
Alzheimer's Disease
PMID 30805717 2019 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis.
rs56039743 in
UBXN11 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs137875858 in
UNC5C gene and
Alzheimer's Disease
PMID 25419706 2014 On the basis of these data and the enriched hippocampal expression of UNC5C in the adult nervous system, we propose that one possible mechanism in which T835M UNC5C contributes to the risk of Alzheimer's disease is by increasing susceptibility to neuronal cell death, particularly in vulnerable regions of the Alzheimer's disease brain.
PMID 27068745 2016 An Alzheimer Disease-linked Rare Mutation Potentiates Netrin Receptor Uncoordinated-5C-induced Signaling That Merges with Amyloid β Precursor Protein Signaling.
rs1385600 in
USP35;GAB2 gene and
Alzheimer's Disease
PMID 17553421 2007 GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
PMID 21460841 2011 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
rs9934540 in
VAT1L gene and
Alzheimer's Disease
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs1033301 in
VSNL1 gene and
Alzheimer's Disease
PMID 22005930 2012 Genome-wide association study of Alzheimer's disease with psychotic symptoms.
PMID 22005930 2012 SNPs upstream of SLC2A9 (rs6834555, P=3.0 × 10(-7)) and within VSNL1 (rs4038131, P=5.9 × 10(-7)) showed strongest evidence for association with AD+P when compared with controls.
rs181666690 in
WAC gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs116300850 in
WDR41 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs6714710 in
ZAP70 gene and
Alzheimer's Disease
PMID 26993346 2016 Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease.
rs1476679 in
ZCWPW1 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
rs1925690 in
ZNF292 gene and
Alzheimer's Disease
PMID 21116278 2011 Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.
rs2927694 in
ZNF813 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
rs116932763 in
ZNF862 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.