Gene: CCRL2

Alternate names for this Gene: ACKR5|CKRX|CRAM|CRAM-A|CRAM-B|HCR

Gene Summary: This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.

Gene is located in Chromosome: 3

Location in Chromosome : 3p21.31

Description of this Gene: C-C motif chemokine receptor like 2

Type of Gene: protein-coding

Gene: CCR5AS

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rs6808835 in CCRL2;CCR5AS gene and Alzheimer's Disease PMID 25340798 2014 Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.