Gene: CDAN1

Alternate names for this Gene: CDA1|CDAI|CDAN1A|DLT|PRO1295

Gene Summary: This gene encodes a protein that appears to play a role in nuclear envelope integrity, possibly related to microtubule attachments. Mutations in this gene cause congenital dyserythropoietic anemia type I, a disease resulting in morphological and functional abnormalities of erythropoiesis.

Gene is located in Chromosome: 15

Location in Chromosome : 15q15.2

Description of this Gene: codanin 1

Type of Gene: protein-coding

rs12594483 in CDAN1 gene and Bipolar Disorder PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.

rs120074166 in CDAN1 gene and Congenital dyserythropoietic anemia, type I PMID 12434312 2002 Congenital dyserythropoietic anemia type I is caused by mutations in codanin-1.

PMID 16141353 2006 Congenital dyserythropoietic anemia type I (CDA I): molecular genetics, clinical appearance, and prognosis based on long-term observation.

PMID 16754775 2006 Linkage and mutational analysis of the CDAN1 gene reveals genetic heterogeneity in congenital dyserythropoietic anemia type I.

PMID 29901818 2018 Clinical and genetic features of congenital dyserythropoietic anemia (CDA).

PMID 18575862 2008 Congenital dyserythropoietic anemia in a Chinese family with a mutation of the CDAN1-gene.

PMID 22407294 2012 Codanin-1, mutated in the anaemic disease CDAI, regulates Asf1 function in S-phase histone supply.

rs112968809 in CDAN1 gene and Depressed bipolar I disorder PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.

rs16957091 in CDAN1 gene and Smoking PMID 26183928 2015 Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung.

rs16957091 in CDAN1 gene and Smoking Behaviors PMID 26183928 2015 Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung.