Gene: CERS2

Alternate names for this Gene: L3|LASS2|SP260|TMSG1

Gene Summary: This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described.

Gene is located in Chromosome: 1

Location in Chromosome : 1q21.3

Description of this Gene: ceramide synthase 2

Type of Gene: protein-coding

rs267738 in CERS2 gene and Creatinine measurement, serum (procedure) PMID 28452372 2017 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.

rs267738 in CERS2 gene and Glomerular Filtration Rate PMID 31152163 2019 A catalog of genetic loci associated with kidney function from analyses of a million individuals.

PMID 31015462 2019 Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis.

PMID 28452372 2017 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.

PMID 30604766 2019 Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.

rs267738 in CERS2 gene and High density lipoprotein measurement PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.

rs267738 in CERS2 gene and Rhegmatogenous retinal detachment PMID 23585552 2013 Genome-wide association study identifies genetic risk underlying primary rhegmatogenous retinal detachment.