Gene: CHL1

Alternate names for this Gene: CALL|L1CAM2

Gene Summary: The protein encoded by this gene is a member of the L1 gene family of neural cell adhesion molecules. It is a neural recognition molecule that may be involved in signal transduction pathways. The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome. This protein may also play a role in the growth of certain cancers. Alternate splicing results in both coding and non-coding variants.

Gene is located in Chromosome: 3

Location in Chromosome : 3p26.3

Description of this Gene: cell adhesion molecule L1 like

Type of Gene: protein-coding

rs892295 in CHL1 gene and Alanine aminotransferase measurement PMID 23251661 2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

rs892295 in CHL1 gene and Aspartate aminotransferase measurement PMID 23251661 2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

rs9809528 in CHL1 gene and Hair Color PMID 30531825 2018 Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability.

rs892295 in CHL1 gene and Polysomnography PMID 23251661 2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

rs892295 in CHL1 gene and Serum Alanine Aminotransferase Measurement PMID 23251661 2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.