Gene: CORO1C

Alternate names for this Gene: HCRNN4

Gene Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Three transcript variants encoding two different isoforms have been found for this gene.

Gene is located in Chromosome: 12

Location in Chromosome : 12q24.11

Description of this Gene: coronin 1C

Type of Gene: protein-coding

rs3741782 in CORO1C gene and Coronary Artery Disease PMID 30525989 2018 Bivariate Genome-Wide Association Scan Identifies 6 Novel Loci Associated With Lipid Levels and Coronary Artery Disease.

rs750134 in CORO1C gene and High density lipoprotein measurement PMID 26879886 2016 A common variant association study reveals novel susceptibility loci for low HDL-cholesterol levels in ethnic Arabs.

rs4964273 in CORO1C gene and Intelligence PMID 29844566 2018 Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

rs3741782 in CORO1C gene and Low density lipoprotein cholesterol measurement PMID 30525989 2018 Bivariate Genome-Wide Association Scan Identifies 6 Novel Loci Associated With Lipid Levels and Coronary Artery Disease.