Gene: CPNE8

Alternate names for this Gene: -

Gene Summary: Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus.

Gene is located in Chromosome: 12

Location in Chromosome : 12q12

Description of this Gene: copine 8

Type of Gene: protein-coding

rs185880008 in CPNE8 gene and Bipolar Disorder PMID 28115744 2018 A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.

rs4595586 in CPNE8 gene and Circadian Rhythms PMID 26835600 2016 GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person.

rs826838 in CPNE8 gene and RESTING HEART RATE PMID 29769521 2018 Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system.

rs826838 in CPNE8 gene and heart rate PMID 23583979 2013 Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.