Gene: CRKL
Alternate names for this Gene: -
Gene Summary: This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Gene is located in Chromosome: 22
Location in Chromosome : 22q11.21
Description of this Gene: CRK like proto-oncogene, adaptor protein
Type of Gene: protein-coding