Gene: CSMD2

Alternate names for this Gene: dJ1007G16.1|dJ1007G16.2|dJ947L8.1

Gene Summary: The protein encoded by this gene is thought to be involved in the control of complement cascade of the immune system. Defects in this gene have been associated with schizophrenia. This gene may act as a tumor suppressor for colorectal cancer.

Gene is located in Chromosome: 1

Location in Chromosome : 1p35.1

Description of this Gene: CUB and Sushi multiple domains 2

Type of Gene: protein-coding

rs2281597 in CSMD2 gene and Attention deficit hyperactivity disorder PMID 18839057 2008 Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.

rs9662615 in CSMD2 gene and Bipolar Disorder PMID 26806518 2016 Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.

rs12031634 in CSMD2 gene and Body mass index PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs79024726 in CSMD2 gene and Endometrial Carcinoma PMID 30093612 2018 Identification of nine new susceptibility loci for endometrial cancer.

rs16835742 in CSMD2 gene and Intelligence PMID 22449649 2012 Genome-wide association study of intelligence: additive effects of novel brain expressed genes.

rs11590251 in CSMD2 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

rs506546 in CSMD2 gene and Major Depressive Disorder PMID 25897834 2015 The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response.

rs506546 in CSMD2 gene and response to SSRI PMID 25897834 2015 The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response.