Gene: DNAJB4
Alternate names for this Gene: DNAJW|DjB4|HLJ1
Gene Summary: The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene.
Gene is located in Chromosome: 1
Location in Chromosome : 1p31.1
Description of this Gene: DnaJ heat shock protein family (Hsp40) member B4
Type of Gene: protein-coding
Gene: GIPC2
Alternate names for this Gene: SEMCAP-2|SEMCAP2
Gene Summary:
Gene is located in Chromosome: 1
Location in Chromosome : 1p31.1
Description of this Gene: GIPC PDZ domain containing family member 2
Type of Gene: protein-coding