Gene: DOCK6
Alternate names for this Gene: AOS2|ZIR1
Gene Summary: This gene encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with small GTPases and are components of intracellular signaling networks. The encoded protein is a group C DOCK protein and plays a role in actin cytoskeletal reorganization by activating the Rho GTPases Cdc42 and Rac1. Mutations in this gene are associated with Adams-Oliver syndrome 2.
Gene is located in Chromosome: 19
Location in Chromosome : 19p13.2
Description of this Gene: dedicator of cytokinesis 6
Type of Gene: protein-coding