Gene: EDN1
Alternate names for this Gene: ARCND3|ET1|HDLCQ7|PPET1|QME
Gene Summary: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
Gene is located in Chromosome: 6
Location in Chromosome : 6p24.1
Description of this Gene: endothelin 1
Type of Gene: protein-coding