Gene: EIF3G
Alternate names for this Gene: EIF3-P42|EIF3S4|eIF3-delta|eIF3-p44
Gene Summary: This gene encodes a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex, which is required for initiation of protein translation. An N-terminal caspase cleavage product of the encoded protein may stimulate degradation of DNA. A mutation in this gene is associated with narcolepsy.
Gene is located in Chromosome: 19
Location in Chromosome : 19p13.2
Description of this Gene: eukaryotic translation initiation factor 3 subunit G
Type of Gene: protein-coding
Gene: PPAN-P2RY11
Alternate names for this Gene: BXDC3|P2RY11|P2Y11|PPAN|SSF1|Ssf-1
Gene Summary: This locus represents naturally occurring read-through transcription between the adjacent PPAN and P2RY11 genes. Alternative splicing results in two transcript variants, one of which encodes a fusion protein that shares sequence identity with each individual gene product. This transcript is found to be ubiquitously expressed and is up-regulated by agents inducing granulocytic differentiation. However, its functional significance in vivo remains unclear.
Gene is located in Chromosome: 19
Location in Chromosome : 19p13.2
Description of this Gene: PPAN-P2RY11 readthrough
Type of Gene: protein-coding
Gene: P2RY11
Alternate names for this Gene: P2Y11
Gene Summary: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product.
Gene is located in Chromosome: 19
Location in Chromosome : 19p13.2
Description of this Gene: purinergic receptor P2Y11
Type of Gene: protein-coding