Gene: ERLIN1
Alternate names for this Gene: C10orf69|Erlin-1|KE04|KEO4|SPFH1|SPG62
Gene Summary: The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.
Gene is located in Chromosome: 10
Location in Chromosome : 10q24.31
Description of this Gene: ER lipid raft associated 1
Type of Gene: protein-coding