Gene: FGF21

Alternate names for this Gene: -

Gene Summary: Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.33

Description of this Gene: fibroblast growth factor 21

Type of Gene: protein-coding

Gene: FUT1

Alternate names for this Gene: H|HH|HSC

Gene Summary: This gene encodes a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the synthesis of soluble A and B antigens. This is one of two genes encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.33

Description of this Gene: fucosyltransferase 1 (H blood group)

Type of Gene: protein-coding

rs838133 in FGF21;FUT1 gene and Homocysteine measurement PMID 23824729 2013 Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.

rs838133 in FGF21;FUT1 gene and Sodium measurement PMID 31409800 2019 GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits.

rs838133 in FGF21;FUT1 gene and Triglycerides measurement PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.