Gene: FRMD4A
Alternate names for this Gene: CCAFCA|FRMD4|bA295P9.4
Gene Summary: This gene encodes a FERM domain-containing protein that regulates epithelial cell polarity. It connects ADP ribosylation factor 6 (ARF6) with the Par protein complex, which regulates the remodeling of adherens junctions and linear actin cable formation during epithelial cell polarization. Polymorphisms in this gene are associated with Alzheimer's disease, and also with nicotine dependence. Alternative splicing results in multiple transcript variants.
Gene is located in Chromosome: 10
Location in Chromosome : 10p13
Description of this Gene: FERM domain containing 4A
Type of Gene: protein-coding