Gene: G3BP1

Alternate names for this Gene: G3BP|HDH-VIII

Gene Summary: This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Gene is located in Chromosome: 5

Location in Chromosome : 5q33.1

Description of this Gene: G3BP stress granule assembly factor 1

Type of Gene: protein-coding