Gene: GPR35
Alternate names for this Gene: -
Gene Summary:
Gene is located in Chromosome: 2
Location in Chromosome : 2q37.3
Description of this Gene: G protein-coupled receptor 35
Type of Gene: protein-coding
rs4676410 in
GPR35 gene and
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1
PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
rs4676410 in
GPR35 gene and
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 2
PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
rs4676410 in
GPR35 gene and
AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 6
PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
rs3749171 in
GPR35 gene and
Ankylosing spondylitis
PMID 26974007 2016 Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
PMID 23749187 2013 Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci.
rs4676410 in
GPR35 gene and
Autoimmune Diseases
PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
rs4676410 in
GPR35 gene and
Autoimmune thyroiditis
PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
rs4676410 in
GPR35 gene and
Celiac Disease
PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
rs3749171 in
GPR35 gene and
Cholangitis, Sclerosing
PMID 26974007 2016 Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
PMID 22821403 2013 Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4.
rs4676410 in
GPR35 gene and
Common Variable Immunodeficiency
PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
rs3749171 in
GPR35 gene and
Crohn Disease
PMID 26974007 2016 Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
PMID 25489960 2015 We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.
PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
rs4676410 in
GPR35 gene and
Diabetes Mellitus, Insulin-Dependent
PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
rs4676410 in
GPR35 gene and
Eosinophil count procedure
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs3749171 in
GPR35 gene and
Inflammatory Bowel Diseases
PMID 23128233 2012 Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
PMID 26192919 2015 Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
rs4676410 in
GPR35 gene and
Juvenile arthritis
PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
rs4676410 in
GPR35 gene and
Lupus Erythematosus, Systemic
PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
rs34236350 in
GPR35 gene and
Monocyte count procedure
PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
rs34236350 in
GPR35 gene and
Monocyte count result
PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
rs3749171 in
GPR35 gene and
Psoriasis
PMID 26974007 2016 Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
rs3749171 in
GPR35 gene and
Ulcerative Colitis
PMID 29562276 2018 Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis.
PMID 26974007 2016 Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
PMID 26192919 2015 Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.