rs3132610 in ABCF1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs2303745 in ABHD8;DDA1 gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

rs77150043 in ADCY7 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs2066363 in ADGRL2 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs340630 in AFF1 gene and Lupus Erythematosus, Systemic

PMID 22291604 2012 In addition, we identified a novel association of a variant in the AF4/FMR2 family, member 1 (AFF1) gene at 4q21 with SLE susceptibility (rs340630; P = 8.3×10(-9), odds ratio = 1.21).

rs11154801 in AHI1 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs7100025 in ANKRD30A;LINC00993 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs4850410 in ANKRD44 gene and Lupus Erythematosus, Systemic

PMID 25338677 2015 Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus.

rs7731626 in ANKRD55 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs1535001 in ANKS1A gene and Lupus Erythematosus, Systemic

PMID 23740937 2013 A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs1217393 in AP4B1-AS1 gene and Lupus Erythematosus, Systemic

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

rs2476601 in AP4B1-AS1;PTPN22 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 27193031 2017 A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus.

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

rs494003 in AP5B1 gene and Lupus Erythematosus, Systemic

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

rs2269368 in ARHGAP4 gene and Lupus Erythematosus, Systemic

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

rs4948496 in ARID5B gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs11013210 in ARMC3 gene and Lupus Erythematosus, Systemic

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

rs36001488 in ATG16L1 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs2299864 in ATG5 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 23740937 2013 A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

PMID 19838193 2009 Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

PMID 27193031 2017 A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus.

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

rs2071591 in ATP6V1G2-DDX39B;ATP6V1G2;NFKBIL1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs370504038 in ATRIP-TREX1;ATRIP;SHISA5;TREX1 gene and Lupus Erythematosus, Systemic

PMID 17660818 2007 Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

PMID 23979357 2013 The TREX1 C-terminal region controls cellular localization through ubiquitination.

PMID 20131292 2010 Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutières syndrome.

rs762011967 in ATRIP-TREX1;ATRIP;TREX1 gene and Lupus Erythematosus, Systemic

PMID 23979357 2013 The TREX1 C-terminal region controls cellular localization through ubiquitination.

PMID 20131292 2010 Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutières syndrome.

PMID 17660818 2007 Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

rs72556554 in ATRIP;TREX1;ATRIP-TREX1 gene and Lupus Erythematosus, Systemic

PMID 17660818 2007 Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

PMID 23979357 2013 The TREX1 C-terminal region controls cellular localization through ubiquitination.

PMID 20131292 2010 Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutières syndrome.

rs17603856 in ATXN1 gene and Lupus Erythematosus, Systemic

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs10774625 in ATXN2 gene and Lupus Erythematosus, Systemic

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs12928404 in ATXN2L gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs597325 in BACH2 gene and Lupus Erythematosus, Systemic

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

rs1077393 in BAG6 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs3117582 in BAG6;APOM gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs10028805 in BANK1 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 18204447 2008 In a genome-wide scan using 85,042 SNPs, we identified an association between SLE and a nonsynonymous substitution (rs10516487, R61H) in the B-cell scaffold protein with ankyrin repeats gene, BANK1.

PMID 18204447 2008 Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs13277113 in BLK gene and Lupus Erythematosus, Systemic

PMID 18204098 2008 Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.

PMID 19838193 2009 Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

PMID 23053960 2012 Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis.

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

PMID 19165918 2008 Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.

PMID 26663301 2016 Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

rs13195509 in BTN2A1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs1980493 in BTNL2;TSBP1-AS1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs229541 in C1QTNF6 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs11580078 in C1orf141;IL23R gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs558702 in C2;ZBTB12;CYP21A2 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs1108131 in CAMK1D gene and Lupus Erythematosus, Systemic

PMID 26980576 2016 Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus.

rs11145763 in CARD9 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs35789010 in CARMIL1 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs2731763 in CCDC113;LOC105371293 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs5754467 in CCDC116;YDJC gene and Lupus Erythematosus, Systemic

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

rs223889 in CCL22 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs704853 in CD247 gene and Lupus Erythematosus, Systemic

PMID 22004975 2012 The association of CD247 with SLE in Asian populations was confirmed (rs704853: odds ratio [OR] = 0.

rs4810485 in CD40 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs2222631 in CD80 gene and Lupus Erythematosus, Systemic

PMID 25862617 2016 Single nuclear polymorphism rs2222631 was found associated with SLE with genome-wide significance (P_all=4.5E-08, OR=0.86) and is independent of rs6804441 in CD80, whose association was reported previously.

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

rs58688157 in CDHR5 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs34330 in CDKN1B;GPR19 gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

rs7683537 in CENPU gene and Lupus Erythematosus, Systemic

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

rs586995 in CEPT1 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs1270942 in CFB;CYP21A2 gene and Lupus Erythematosus, Systemic

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs12599402 in CLEC16A gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

rs9603612 in COG6 gene and Lupus Erythematosus, Systemic

PMID 27193031 2017 A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus.

rs6689858 in CRB1 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs12822507 in CREBL2 gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

rs3130618 in CSNK2B;GPANK1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs887369 in CXorf21 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs2242665 in CYP21A2;SLC44A4 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs389883 in CYP21A2;STK19 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs4625 in DAG1 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs12615624 in DARS1 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs41264285 in DCST1-AS1;ADAM15 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs9398235 in DDO gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs13101828 in DGKQ gene and Lupus Erythematosus, Systemic

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs4852324 in DGUOK-AS1 gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

rs35677470 in DNASE1L3 gene and Lupus Erythematosus, Systemic

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

rs4622329 in DRAM1 gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

rs652888 in EHMT2-AS1;EHMT2;LOC107986588;CYP21A2 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs535586 in EHMT2;CYP21A2 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs659445 in EHMT2;CYP21A2;C2 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs7329174 in ELF1 gene and Lupus Erythematosus, Systemic

PMID 21044949 2011 Although a direct association of rs7329174 with the three forms of transcripts for this gene was not detected, these findings support an important role of ELF1 in SLE susceptibility and suggest a potentially tight regulation for the expression of this gene.

rs4869313 in ERAP2;ERAP1 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs1128334 in ETS1 gene and Lupus Erythematosus, Systemic

PMID 20169177 2010 By a genome-wide association study (320 patients and 1,500 controls) and subsequent replication altogether involving a total of 3,300 Asian SLE patients from Hong Kong, Mainland China, and Thailand, as well as 4,200 ethnically and geographically matched controls, genetic variants in ETS1 and WDFY4 were found to be associated with SLE (ETS1: rs1128334, P = 2.33x10(-11), OR = 1.29; WDFY4: rs7097397, P = 8.15x10(-12), OR = 1.30).

PMID 26663301 2016 Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

rs11578098 in EVI5 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs7836059 in FAM167A-AS1 gene and Lupus Erythematosus, Systemic

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

rs2955587 in FAM86B3P gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs11073328 in FAM98B gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs1801274 in FCGR2A gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

rs10988542 in FNBP1 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs1235162 in GABBR1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs11845506 in GALC gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs7300146 in GLT1D1 gene and Lupus Erythematosus, Systemic

PMID 29967481 2018 In conclusion, cSLE is associated with a high cumulative SLE-risk effect and two novel SNPs rs7460469 and rs7300146, providing the first predictive model for cSLE in Koreans.

rs10845606 in GPR19 gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

rs4676410 in GPR35 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs204990 in GPSM3 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs36023980 in GRB2 gene and Lupus Erythematosus, Systemic

PMID 29848360 2018 Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus.

rs2267828 in GTF2IRD1 gene and Lupus Erythematosus, Systemic

PMID 26663301 2016 Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

rs200953 in H1-5 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs13194781 in H2BC15 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs3129791 in HCG15 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs2844773 in HCG17;TRIM26BP gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs3130380 in HCG18;HCG17 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs3132580 in HCG21;SFTA2;MUCL3 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs2395488 in HCP5 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs1167796 in HIP1 gene and Lupus Erythematosus, Systemic

PMID 19838193 2009 Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

PMID 26663301 2016 Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

rs3132685 in HLA-A;HCG9 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs2596501 in HLA-B gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs6457374 in HLA-B;LOC112267902 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs1480380 in HLA-DMB gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs9273076 in HLA-DQA1;LOC107986589 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs2051549 in HLA-DQB2 gene and Lupus Erythematosus, Systemic

PMID 23053960 2012 The most significant result of SLE GWAS meta-analysis concerned rs2051549 in the human leukocyte antigen (HLA) region (p = 3.36E-22).

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

PMID 21408207 2011 Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

rs2239804 in HLA-DRA gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

rs660895 in HLA-DRB1 gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

PMID 19838193 2009 Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

rs9268832 in HLA-DRB9 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs3094073 in HLA-L;HCG17 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs6904596 in HNRNPA1P1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs2763979 in HSPA1B gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs12129787 in HSPA6;FCGR2A gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs10156091 in ICA1 gene and Lupus Erythematosus, Systemic

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs7258015 in ICAM3 gene and Lupus Erythematosus, Systemic

PMID 27193031 2017 A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus.

rs1990760 in IFIH1 gene and Lupus Erythematosus, Systemic

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs2041862 in IFNG-AS1;LOC107984526 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs17885785 in IGF2;IGF2-AS;INS-IGF2 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs2297550 in IKBKE gene and Lupus Erythematosus, Systemic

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

rs10048743 in IKZF2 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

rs143123127 in IKZF3 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 31407831 2019 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.

rs564799 in IL12A-AS1 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs10889681 in IL12RB2 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

rs11681718 in IL18RAP gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs3122605 in IL19 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs3024493 in IL19;IL10 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs62324212 in IL21-AS1 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs706778 in IL2RA gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs7764921 in ILRUN gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

rs1059702 in IRAK1 gene and Lupus Erythematosus, Systemic

PMID 26606652 2016 Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.

rs11741255 in IRF1-AS1 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs10954214 in IRF5 gene and Lupus Erythematosus, Systemic

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

PMID 26663301 2016 Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

PMID 21408207 2011 Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

rs1061502 in IRF7 gene and Lupus Erythematosus, Systemic

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs112006329 in IRF7;CDHR5 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs1143678 in ITGAM gene and Lupus Erythematosus, Systemic

PMID 19286673 2009 ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai.

PMID 21408207 2011 Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 26606652 2016 Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 23740937 2013 A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs11574637 in ITGAX gene and Lupus Erythematosus, Systemic

PMID 18204098 2008 In addition, variants on chromosome 16p11.22, near the genes encoding integrin alpha M (ITGAM, or CD11b) and integrin alpha X (ITGAX), were associated with SLE in the combined sample (rs11574637; odds ratio, 1.33; P=3x10(-11)).

PMID 21408207 2011 Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

rs3748079 in ITPR3 gene and Lupus Erythematosus, Systemic

PMID 18219441 2008 Here we report that an SNP (rs3748079) located in a promoter region of the inositol 1,4,5-triphosphate receptor type 3 (ITPR3) gene on chromosome 6p21 was significantly associated with SLE in two independent Japanese case-control samples [P=0.0000000178 with odds ratio of 1.88, 95% confidence interval (CI) of 1.51-2.35].

rs1887428 in JAK2 gene and Lupus Erythematosus, Systemic

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

rs10245867 in JAZF1 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 23740937 2013 A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

rs1444766 in KALRN gene and Lupus Erythematosus, Systemic

PMID 31407831 2019 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.

rs169080 in KDM4B gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs2275247 in KIAA0319L gene and Lupus Erythematosus, Systemic

PMID 23740937 2013 A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

rs2855772 in KIT gene and Lupus Erythematosus, Systemic

PMID 29494758 2018 Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese.

rs525410 in LAMC2 gene and Lupus Erythematosus, Systemic

PMID 21408207 2011 Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

rs17321999 in LBH gene and Lupus Erythematosus, Systemic

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

rs886424 in LINC00243 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs10032909 in LINC01088 gene and Lupus Erythematosus, Systemic

PMID 26606652 2016 Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.

rs1432296 in LINC01185 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs114846446 in LINC01250 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs461193 in LINC01511 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs6869688 in LINC01845 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs3117143 in LOC100129636 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs1041981 in LOC100287329;LTA gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs10753074 in LOC100506023;TNFSF4 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 26606652 2016 Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

PMID 23740937 2013 A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

rs1267499 in LOC101928354 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs10466455 in LOC102723568 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs4639966 in LOC105369519 gene and Lupus Erythematosus, Systemic

PMID 19838193 2009 Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

rs17466626 in LOC105369736;LRRK2 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs3117426 in LOC105375005;OR14J1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs1966115 in LOC105375911 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs7090925 in LOC105376397 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs2732549 in LOC105376626 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

rs353592 in LOC105376627 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs877819 in LOC105378299;WDFY4 gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

rs4388254 in LOC105379185 gene and Lupus Erythematosus, Systemic

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs602662 in LOC105447645;FUT2 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs958476 in LOC107984410;BARX2 gene and Lupus Erythematosus, Systemic

PMID 26980576 2016 Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus.

rs9311676 in LOC107986092 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs2187668 in LOC107986589;HLA-DQA2;HLA-DQA1 gene and Lupus Erythematosus, Systemic

PMID 18204098 2008 Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

PMID 21408207 2011 Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

PMID 26316170 2016 Identification of a New Susceptibility Locus for Systemic Lupus Erythematosus on Chromosome 12 in Individuals of European Ancestry.

rs7834765 in LOC107986971 gene and Lupus Erythematosus, Systemic

PMID 24925725 2014 Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.

rs7819602 in LOC112268022 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs6762714 in LPP gene and Lupus Erythematosus, Systemic

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

rs1913517 in LRRC18;WDFY4 gene and Lupus Erythematosus, Systemic

PMID 19838193 2009 Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

rs912784 in LRRC63;LOC107984578;LCP1 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs7042370 in LURAP1L-AS1;LURAP1L gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs9267531 in LY6G5B;CSNK2B gene and Lupus Erythematosus, Systemic

PMID 26316170 2016 Identification of a New Susceptibility Locus for Systemic Lupus Erythematosus on Chromosome 12 in Individuals of European Ancestry.

rs805294 in LY6G6C;MPIG6B gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs2667978 in LYN gene and Lupus Erythematosus, Systemic

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

rs4660116 in LYST gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

rs1734787 in MECP2 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs1039917 in MFHAS1 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs11887156 in MGAT5 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 31407831 2019 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.

rs2251396 in MICA-AS1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs2855812 in MICB gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs3099844 in MICB-DT gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs4252665 in MIEN1;ERBB2 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs12802200 in MIR210HG gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs3131379 in MSH5;MSH5-SAPCD1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

PMID 26316170 2016 Identification of a New Susceptibility Locus for Systemic Lupus Erythematosus on Chromosome 12 in Individuals of European Ancestry.

rs886403 in MUC21 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs1634718 in MUC22 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs3794060 in NADSYN1 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs13306575 in NCF2;SMG7 gene and Lupus Erythematosus, Systemic

PMID 26606652 2016 Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs630379 in NELFE;CYP21A2 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs8012283 in NIN gene and Lupus Erythematosus, Systemic

PMID 24925725 2014 Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.

rs117372389 in NKD1 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs17484292 in NMNAT2 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

rs835573 in NOTCH2 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs3131296 in NOTCH4 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs3749971 in OR12D3;OR5V1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs62149377 in PAPOLG gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs204994 in PBX2 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs13211507 in PGBD1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs4963128 in PHRF1 gene and Lupus Erythematosus, Systemic

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

rs6679677 in PHTF1 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs1804182 in PLAT gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs2196171 in PLCL1 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs2286672 in PLD2 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs1048257 in PLD4;AHNAK2 gene and Lupus Erythematosus, Systemic

PMID 26663301 2016 Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

rs1049564 in PNP gene and Lupus Erythematosus, Systemic

PMID 25338677 2015 Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus.

rs9262143 in PPP1R18 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs12664535 in PRIM2 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs7897633 in PRKG1 gene and Lupus Erythematosus, Systemic

PMID 25338677 2015 Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus.

rs76246107 in PRR12 gene and Lupus Erythematosus, Systemic

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

rs1046089 in PRRC2A gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs3115663 in PRRC2A;MIR6832 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs3130564 in PSORS1C1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs11066301 in PTPN11 gene and Lupus Erythematosus, Systemic

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

rs11590283 in PUSL1 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs12156002 in PVT1 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs180977001 in PXK gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 23740937 2013 A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

rs4902562 in RAD51B gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs13385731 in RASGRP3 gene and Lupus Erythematosus, Systemic

PMID 19838193 2009 Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 26663301 2016 Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

rs9261290 in RNF39 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs3134945 in RNF5;MIR6833;AGPAT1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs1749792 in RNU4-36P;ZFP90 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs4917385 in RPEL1 gene and Lupus Erythematosus, Systemic

PMID 26606652 2016 Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.

rs2953898 in RPS20 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs10995092 in RTKN2 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs1133906 in SAMD9L gene and Lupus Erythematosus, Systemic

PMID 23740937 2013 A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

rs9889107 in SBK1 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs2289583 in SCAMP5 gene and Lupus Erythematosus, Systemic

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs11057864 in SCARB1 gene and Lupus Erythematosus, Systemic

PMID 26980576 2016 Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus.

rs2071725 in SCUBE1;LOC105373051 gene and Lupus Erythematosus, Systemic

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

rs7795074 in SKAP2 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs437179 in SKIV2L;CYP21A2 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs1878186 in SLC12A1;LOC112267905 gene and Lupus Erythematosus, Systemic

PMID 26606652 2016 Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.

rs1059312 in SLC15A4 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

PMID 19838193 2009 Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

rs494620 in SLC44A4;CYP21A2 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs274068 in SLC5A11 gene and Lupus Erythematosus, Systemic

PMID 24925725 2014 Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.

rs72743477 in SMAD3 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs10911363 in SMG7;NCF2 gene and Lupus Erythematosus, Systemic

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs1780813 in SMYD3 gene and Lupus Erythematosus, Systemic

PMID 29848360 2018 Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus.

rs497273 in SPPL3 gene and Lupus Erythematosus, Systemic

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

rs268134 in SPRED2 gene and Lupus Erythematosus, Systemic

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs55849330 in ST8SIA4 gene and Lupus Erythematosus, Systemic

PMID 29848360 2018 Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus.

rs10168266 in STAT4 gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

PMID 21408207 2011 Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 26606652 2016 Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 26663301 2016 Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

PMID 19165918 2008 Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.

PMID 18204098 2008 Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.

PMID 21408207 2011 For example, rs7574865 in STAT4 had an OR for anti-dsDNA + SLE of 1.77 (95% CI 1.57-1.99, p = 2.0E-20) compared to an OR for anti-dsDNA - SLE of 1.26 (95% CI 1.12-1.41, p = 2.4E-04), with p(heterogeneity)<0.0005.

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

PMID 19838193 2009 Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

PMID 23053960 2012 Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis.

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

PMID 26316170 2016 Identification of a New Susceptibility Locus for Systemic Lupus Erythematosus on Chromosome 12 in Individuals of European Ancestry.

PMID 23740937 2013 A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

rs389884 in STK19;CYP21A2;DXO gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs10819689 in STX17-AS1;LOC101928438 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs11788118 in STX17-AS1;LOC107987012 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs1689510 in SUOX gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs17005500 in SYT1 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs428073 in TAOK3 gene and Lupus Erythematosus, Systemic

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

rs7750641 in TCF19 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs9394274 in TCP11 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs10069690 in TERT gene and Lupus Erythematosus, Systemic

PMID 31407831 2019 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.

rs6705628 in TET3;DGUOK-AS1 gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

rs1131265 in TIMMDC1 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs12636784 in TMEM39A gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs56154925 in TMEM86B gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs2230926 in TNFAIP3 gene and Lupus Erythematosus, Systemic

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 19838193 2009 Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

PMID 26663301 2016 Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

PMID 19165918 2008 We carried out a genome-wide association scan and replication study and found an association between SLE and a variant in TNFAIP3 (rs5029939, meta-analysis P = 2.89 x 10(-12), OR = 2.29).

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs5029924 in TNFAIP3;WAKMAR2 gene and Lupus Erythematosus, Systemic

PMID 27193031 2017 A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus.

rs4246905 in TNFSF15 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs2205960 in TNFSF4 gene and Lupus Erythematosus, Systemic

PMID 19838193 2009 Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

rs1012507 in TNFSF4;LOC100506023 gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

PMID 18204446 2008 Aside from the expected strong association between SLE and the HLA region on chromosome 6p21 and the previously confirmed non-HLA locus IRF5 on chromosome 7q32, we found evidence of association with replication (1.1 x 10(-7) < P(overall) < 1.6 x 10(-23); odds ratio = 0.82-1.62) in four regions: 16p11.2 (ITGAM), 11p15.5 (KIAA1542), 3p14.3 (PXK) and 1q25.1 (rs10798269).

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 26663301 2016 Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs10036748 in TNIP1 gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 19838193 2009 Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 26606652 2016 Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

PMID 23740937 2013 A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

rs10239340 in TNPO3 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

PMID 21408207 2011 Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

PMID 18204098 2008 Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 23053960 2012 Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis.

PMID 27193031 2017 A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus.

PMID 26606652 2016 Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

rs13239597 in TNPO3;TPI1P2 gene and Lupus Erythematosus, Systemic

PMID 23740937 2013 A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

rs1150753 in TNXB gene and Lupus Erythematosus, Systemic

PMID 26316170 2016 Identification of a New Susceptibility Locus for Systemic Lupus Erythematosus on Chromosome 12 in Individuals of European Ancestry.

PMID 21408207 2011 Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

PMID 18058064 2008 Stratified analysis also revealed that the association of SNP rs3130342 with SLE was independent of the HLA-DRB1*1501 allele that has been shown to be associated with SLE.

rs17630235 in TRAFD1 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs10018951 in TRAPPC11 gene and Lupus Erythematosus, Systemic

PMID 29494758 2018 Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese.

rs72556555 in TREX1;ATRIP-TREX1;SHISA5;ATRIP gene and Lupus Erythematosus, Systemic

PMID 20131292 2010 Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutières syndrome.

PMID 23979357 2013 The TREX1 C-terminal region controls cellular localization through ubiquitination.

PMID 17660818 2007 Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

rs148833270 in TREX1;SHISA5;ATRIP-TREX1;ATRIP gene and Lupus Erythematosus, Systemic

PMID 17660818 2007 Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

PMID 23979357 2013 The TREX1 C-terminal region controls cellular localization through ubiquitination.

PMID 20131292 2010 Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutières syndrome.

rs2523987 in TRIM31-AS1;TRIM31 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs2517598 in TRIM31;TRIM31-AS1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs3115553 in TSBP1-AS1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs1003878 in TSBP1-AS1;TSBP1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

rs6457536 in TSBP1;TSBP1-AS1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs11085725 in TYK2 gene and Lupus Erythematosus, Systemic

PMID 30573655 2019 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs131654 in UBE2L3 gene and Lupus Erythematosus, Systemic

PMID 19838193 2009 Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 27193031 2017 A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus.

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs11755393 in UHRF1BP1 gene and Lupus Erythematosus, Systemic

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

rs707928 in VWA7 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs3757173 in WAKMAR2;TNFAIP3 gene and Lupus Erythematosus, Systemic

PMID 23273568 2013 Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

rs10857635 in WDFY4 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

PMID 26606652 2016 Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 20169177 2010 By a genome-wide association study (320 patients and 1,500 controls) and subsequent replication altogether involving a total of 3,300 Asian SLE patients from Hong Kong, Mainland China, and Thailand, as well as 4,200 ethnically and geographically matched controls, genetic variants in ETS1 and WDFY4 were found to be associated with SLE (ETS1: rs1128334, P = 2.33x10(-11), OR = 1.29; WDFY4: rs7097397, P = 8.15x10(-12), OR = 1.30).

PMID 26663301 2016 Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

rs2663054 in WDFY4;LRRC18 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs11783247 in XKR6 gene and Lupus Erythematosus, Systemic

PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

PMID 29967481 2018 In conclusion, cSLE is associated with a high cumulative SLE-risk effect and two novel SNPs rs7460469 and rs7300146, providing the first predictive model for cSLE in Koreans.

rs3747093 in YDJC gene and Lupus Erythematosus, Systemic

PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs1170426 in ZFP90 gene and Lupus Erythematosus, Systemic

PMID 27399966 2016 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs967005 in ZKSCAN4 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs1250563 in ZMIZ1 gene and Lupus Erythematosus, Systemic

PMID 26301688 2015 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

rs1194 in ZNF76 gene and Lupus Erythematosus, Systemic

PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.

rs8321 in ZNRD1 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs1419183 in ZSCAN26 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

rs853676 in ZSCAN31 gene and Lupus Erythematosus, Systemic

PMID 24871463 2014 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.