Gene: GULOP
Alternate names for this Gene:
Gene Summary:
Gene is located in Chromosome:
Location in Chromosome :
Description of this Gene:
Type of Gene:
Gene: EPHX2
Alternate names for this Gene: ABHD20|CEH|SEH
Gene Summary: This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described.
Gene is located in Chromosome: 8
Location in Chromosome : 8p21.2-p21.1
Description of this Gene: epoxide hydrolase 2
Type of Gene: protein-coding
rs59724122 in
GULOP;EPHX2 gene and
Bipolar Disorder
PMID 29121268 2018 Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
rs11783093 in
GULOP;EPHX2 gene and
Schizophrenia
PMID 29483656 2018 Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
PMID 29121268 2018 Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
PMID 31268507 2019 Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study.
rs11783093 in
GULOP;EPHX2 gene and
Smoking
PMID 30643258 2019 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.