Gene: HAL
Alternate names for this Gene: HIS|HSTD
Gene Summary: Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids. Several transcript variants encoding different isoforms have been found for this gene.
Gene is located in Chromosome: 12
Location in Chromosome : 12q23.1
Description of this Gene: histidine ammonia-lyase
Type of Gene: protein-coding