Gene: ICAM3
Alternate names for this Gene: CD50|CDW50|ICAM-R
Gene Summary: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene is located in Chromosome: 19
Location in Chromosome : 19p13.2
Description of this Gene: intercellular adhesion molecule 3
Type of Gene: protein-coding