Gene: IRF3
Alternate names for this Gene: IIAE7
Gene Summary: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important in the innate immune response against DNA and RNA viruses. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene is located in Chromosome: 19
Location in Chromosome : 19q13.33
Description of this Gene: interferon regulatory factor 3
Type of Gene: protein-coding