Gene: IRF7

Alternate names for this Gene: IMD39|IRF-7|IRF-7H|IRF7A|IRF7B|IRF7C|IRF7H

Gene Summary: IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established.

Gene is located in Chromosome: 11

Location in Chromosome : 11p15.5

Description of this Gene: interferon regulatory factor 7

Type of Gene: protein-coding

Gene: CDHR5

Alternate names for this Gene: MLPCDH|MU-PCDH|MUCDHL|MUPCDH

Gene Summary: This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene is located in Chromosome: 11

Location in Chromosome : 11p15.5

Description of this Gene: cadherin related family member 5

Type of Gene: protein-coding

rs112006329 in IRF7;CDHR5 gene and Lupus Erythematosus, Systemic PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.