Gene: KAT8
Alternate names for this Gene: LIGOWS|MOF|MYST1|ZC2HC8|hMOF
Gene Summary: This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene is located in Chromosome: 16
Location in Chromosome : 16p11.2
Description of this Gene: lysine acetyltransferase 8
Type of Gene: protein-coding
rs59735493 in
KAT8 gene and
Alzheimer's Disease
PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
rs59735493 in
KAT8 gene and
Anxiety
PMID 29942085 2018 Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.
rs9925964 in
KAT8 gene and
Body mass index
PMID 30108127 2018 A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.
PMID 26426971 2015 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
PMID 25673413 2015 Genetic studies of body mass index yield new insights for obesity biology.
PMID 28443625 2017 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
rs9925964 in
KAT8 gene and
Smoking
PMID 28443625 2017 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
rs1549293 in
KAT8 gene and
Waist Circumference
PMID 25673412 2015 New genetic loci link adipose and insulin biology to body fat distribution.