Gene: KCTD10

Alternate names for this Gene: BTBD28|MSTP028|ULRO61|hBACURD3

Gene Summary: The protein encoded by this gene binds proliferating cell nuclear antigen (PCNA) and may be involved in DNA synthesis and cell proliferation. In addition, the encoded protein may be a tumor suppressor. Several protein-coding and non-protein coding transcript variants have been found for this gene.

Gene is located in Chromosome: 12

Location in Chromosome : 12q24.11

Description of this Gene: potassium channel tetramerization domain containing 10

Type of Gene: protein-coding

rs2338104 in KCTD10 gene and Coronary heart disease PMID 21347282 2011 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

rs2058804 in KCTD10 gene and High density lipoprotein measurement PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.

PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.

PMID 18193043 2008 Newly identified loci that influence lipid concentrations and risk of coronary artery disease.

rs2338104 in KCTD10 gene and Serum HDL cholesterol measurement PMID 18193043 2008 Newly identified loci that influence lipid concentrations and risk of coronary artery disease.

PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.