Gene: KDM1B

Alternate names for this Gene: AOF1|C6orf193|LSD2

Gene Summary: Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (Karytinos et al., 2009 [PubMed 19407342]).[supplied by OMIM, Oct 2009].

Gene is located in Chromosome: 6

Location in Chromosome : 6p22.3

Description of this Gene: lysine demethylase 1B

Type of Gene: protein-coding

rs188911996 in KDM1B gene and Alzheimer's Disease PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.

rs34969716 in KDM1B gene and Atrial Fibrillation PMID 30061737 2018 Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.

PMID 29892015 2018 Multi-ethnic genome-wide association study for atrial fibrillation.