Gene: LHPP

Alternate names for this Gene: HDHD2B

Gene Summary:

Gene is located in Chromosome: 10

Location in Chromosome : 10q26.13

Description of this Gene: phospholysine phosphohistidine inorganic pyrophosphate phosphatase

Type of Gene: protein-coding

rs7908284 in LHPP gene and Adolescent idiopathic scoliosis PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs34997829 in LHPP gene and Alcohol-Induced Disorders PMID 27531626 2017 The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene.

rs34997829 in LHPP gene and Alcohol-Related Disorders PMID 27531626 2017 The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene.

rs34997829 in LHPP gene and Alcoholic Intoxication, Chronic PMID 27531626 2017 The clinical relevance of the result was confirmed by the significant interaction between LHPP rs34997829 and AD with respect to self-reported sexually transmitted disease (STD; z=-2.809, p=4.97 × 10<sup>-3</sup>).

rs1563278 in LHPP gene and Body Height PMID 31562340 2019 Characterizing rare and low-frequency height-associated variants in the Japanese population.

PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs145811080 in LHPP gene and Ferritin measurement PMID 28334935 2017 Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?

rs35837782 in LHPP gene and Precursor B-Cell Lymphoblastic Leukemia-Lymphoma PMID 27694927 2017 A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1.

PMID 29632299 2018 Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia.

rs7908284 in LHPP gene and SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs145811080 in LHPP gene and Serum ferritin measurement PMID 28334935 2017 Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?

rs61408740 in LHPP gene and Testicular Germ Cell Tumor PMID 28604732 2017 Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor.