rs12006002 in ADAMTSL1 gene and Alcoholic Intoxication, Chronic

PMID 23089632 2013 A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.

rs1154433 in ADH1B gene and Alcoholic Intoxication, Chronic

PMID 30940813 2019 Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.

PMID 23456092 2013 In case-control analysis, ADH1B rs1229984 (H47R) showed the most significant association with the risk of AD (p = 2.63 × 10(-21), OR = 2.35).

PMID 24166409 2014 Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.

PMID 31090166 2019 In the trans-ancestral meta-analysis, rs1229984 was associated with multiple phenotypes and two additional loci were genome-wide significant: rs61826952 (chromosome 1, DSM-IV AD, P = 8.42E-11); rs7597960 (chromosome 2, Time spent drinking, P = 1.22E-08).

PMID 28714907 2017 Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis.

PMID 22004471 2012 Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.

PMID 31591379 2019 Genome-wide association study of alcohol dependence in male Han Chinese and cross-ethnic polygenic risk score comparison.

rs1612735 in ADH1B;ADH1C gene and Alcoholic Intoxication, Chronic

PMID 30940813 2019 Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.

PMID 24166409 2014 Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.

rs1789924 in ADH1C gene and Alcoholic Intoxication, Chronic

PMID 28714907 2017 Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis.

rs12639833 in ADH1C;ADH1B gene and Alcoholic Intoxication, Chronic

PMID 24166409 2014 Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.

rs5860563 in ADH4;LOC100507053 gene and Alcoholic Intoxication, Chronic

PMID 30940813 2019 Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.

rs147247472 in AGBL4-IT1;AGBL4 gene and Alcoholic Intoxication, Chronic

PMID 31462767 2019 We identified and replicated three novel loci that were associated with the common risk of heroin, methamphetamine addiction, and alcoholism: ANKS1B rs2133896 (P_meta = 3.60 × 10^-9), AGBL4 rs147247472 (P_meta = 3.40 × 10^-12), and CTNNA2 rs10196867 (P_meta = 4.73 × 10^-9).

rs671 in ALDH2 gene and Alcoholic Intoxication, Chronic

PMID 24277619 2014 When rs671 was considered as a candidate SNP in females, it explained 23.6% of the variation in flushing response, but alcohol consumption rates were too low among females-despite familial enrichment for AD-for an adequate test of association for either AD or maximum drinks.

rs2133896 in ANKS1B gene and Alcoholic Intoxication, Chronic

PMID 31462767 2019 We identified and replicated three novel loci that were associated with the common risk of heroin, methamphetamine addiction, and alcoholism: ANKS1B rs2133896 (P_meta = 3.60 × 10^-9), AGBL4 rs147247472 (P_meta = 3.40 × 10^-12), and CTNNA2 rs10196867 (P_meta = 4.73 × 10^-9).

rs2253612 in AOX3P;AOX3P-AOX2P gene and Alcoholic Intoxication, Chronic

PMID 26365420 2015 The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores.

rs35951 in ARL15 gene and Alcoholic Intoxication, Chronic

PMID 24962325 2014 Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.

rs11066001 in BRAP gene and Alcoholic Intoxication, Chronic

PMID 31591379 2019 Genome-wide association study of alcohol dependence in male Han Chinese and cross-ethnic polygenic risk score comparison.

PMID 24277619 2014 "ALDH2 is associated to alcohol dependence and is the major genetic determinant of ""daily maximum drinks"" in a GWAS study of an isolated rural Chinese sample."

rs8040009 in C15orf32 gene and Alcoholic Intoxication, Chronic

PMID 21529783 2011 A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.

rs3743832 in C16orf72 gene and Alcoholic Intoxication, Chronic

PMID 23942779 2013 A genome-wide association study of behavioral disinhibition.

rs10913569 in C1orf220 gene and Alcoholic Intoxication, Chronic

PMID 20202923 2010 A genome-wide association study of alcohol dependence.

rs62313897 in CCSER1 gene and Alcoholic Intoxication, Chronic

PMID 28990359 2017 Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.

rs10211296 in CSRNP3 gene and Alcoholic Intoxication, Chronic

PMID 28990359 2017 Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.

rs10196867 in CTNNA2 gene and Alcoholic Intoxication, Chronic

PMID 31462767 2019 We identified and replicated three novel loci that were associated with the common risk of heroin, methamphetamine addiction, and alcoholism: ANKS1B rs2133896 (P_meta = 3.60 × 10^-9), AGBL4 rs147247472 (P_meta = 3.40 × 10^-12), and CTNNA2 rs10196867 (P_meta = 4.73 × 10^-9).

rs72737330 in ESRRG gene and Alcoholic Intoxication, Chronic

PMID 29071344 2017 Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.

rs2002594 in FAM162A gene and Alcoholic Intoxication, Chronic

PMID 28990359 2017 Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.

rs115460205 in FSTL5 gene and Alcoholic Intoxication, Chronic

PMID 28990359 2017 Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.

rs11075992 in FTO gene and Alcoholic Intoxication, Chronic

PMID 30940813 2019 Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.

rs1260326 in GCKR gene and Alcoholic Intoxication, Chronic

PMID 30940813 2019 Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.

rs1316543 in GRK5 gene and Alcoholic Intoxication, Chronic

PMID 28990359 2017 Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.

rs6060124 in GSS gene and Alcoholic Intoxication, Chronic

PMID 23089632 2013 A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.

rs12898370 in HMG20A gene and Alcoholic Intoxication, Chronic

PMID 28990359 2017 Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.

rs11825659 in IGSF9B gene and Alcoholic Intoxication, Chronic

PMID 29071344 2017 Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.

rs10483038 in KCNJ6 gene and Alcoholic Intoxication, Chronic

PMID 22554406 2012 Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6.

rs2835898 in KCNJ6;LOC107985507 gene and Alcoholic Intoxication, Chronic

PMID 22554406 2012 Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6.

rs1057302 in KIAA0040 gene and Alcoholic Intoxication, Chronic

PMID 21703634 2011 A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.

rs58598658 in KLF12 gene and Alcoholic Intoxication, Chronic

PMID 29071344 2017 Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.

rs34997829 in LHPP gene and Alcoholic Intoxication, Chronic

PMID 27531626 2017 The clinical relevance of the result was confirmed by the significant interaction between LHPP rs34997829 and AD with respect to self-reported sexually transmitted disease (STD; z=-2.809, p=4.97 × 10^-3).

rs6716455 in LINC01818 gene and Alcoholic Intoxication, Chronic

PMID 21529783 2011 A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.

rs55768019 in LINC02268 gene and Alcoholic Intoxication, Chronic

PMID 26365420 2015 The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores.

rs7906104 in LINC02661 gene and Alcoholic Intoxication, Chronic

PMID 30940813 2019 Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.

rs12898460 in LINC02694 gene and Alcoholic Intoxication, Chronic

PMID 23089632 2013 A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.

rs904092 in LOC100507053 gene and Alcoholic Intoxication, Chronic

PMID 24166409 2014 Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.

rs17028615 in LOC100507053;ADH4 gene and Alcoholic Intoxication, Chronic

PMID 24166409 2014 Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.

rs12427267 in LOC105369901 gene and Alcoholic Intoxication, Chronic

PMID 23691058 2013 Dosage transmission disequilibrium test (dTDT) for linkage and association detection.

rs181048070 in LOC105374754 gene and Alcoholic Intoxication, Chronic

PMID 26365420 2015 The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores.

rs1867877 in LOC105376579;IGSF22 gene and Alcoholic Intoxication, Chronic

PMID 28990359 2017 Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.

rs12482570 in LOC107985507;KCNJ6 gene and Alcoholic Intoxication, Chronic

PMID 22554406 2012 Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6.

rs896543 in LOC107986001 gene and Alcoholic Intoxication, Chronic

PMID 23089632 2013 A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.

PMID 24962325 2014 Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.

rs72900220 in LOC112267901 gene and Alcoholic Intoxication, Chronic

PMID 30940813 2019 Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.

rs1800973 in LYZ gene and Alcoholic Intoxication, Chronic

PMID 19581569 2009 Genome-wide association study of alcohol dependence.

rs9458121 in MAP3K4 gene and Alcoholic Intoxication, Chronic

PMID 21956439 2012 Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.

rs9556711 in MBNL2 gene and Alcoholic Intoxication, Chronic

PMID 21529783 2011 A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.

rs9378160 in MICB gene and Alcoholic Intoxication, Chronic

PMID 30940813 2019 Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.

rs12544026 in NCALD gene and Alcoholic Intoxication, Chronic

PMID 29071344 2017 Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.

rs6060038 in NCOA6 gene and Alcoholic Intoxication, Chronic

PMID 23089632 2013 A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.

rs11681792 in NRXN1 gene and Alcoholic Intoxication, Chronic

PMID 23942779 2013 A genome-wide association study of behavioral disinhibition.

rs17754467 in NRXN3 gene and Alcoholic Intoxication, Chronic

PMID 23691058 2013 Dosage transmission disequilibrium test (dTDT) for linkage and association detection.

rs3792686 in NSG1 gene and Alcoholic Intoxication, Chronic

PMID 22096494 2011 A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study.

rs7590720 in PECR;MREG gene and Alcoholic Intoxication, Chronic

PMID 19581569 2009 Genome-wide association study of alcohol dependence.

rs750338 in PKNOX2 gene and Alcoholic Intoxication, Chronic

PMID 21703634 2011 The top hit of PKNOX2 (rs750338 with p=1.47 × 10(-6)) in the meta-analysis was replicated with the Australian Twin-Family Study of 778 families (p=1.39 × 10(-2)) Furthermore, several flanking SNPs of the top hits in the meta-analysis demonstrated borderline associations with alcohol dependence in the family sample (top SNPs were rs2269655, rs856613, and rs10496768 with p=4.58 × 10(-3), 2.1 × 10(-4), and 2.86 × 10(-3) for KIAA0040, NRD1 and THSD7B, respectively).

rs6778524 in PLCL2 gene and Alcoholic Intoxication, Chronic

PMID 21956439 2012 Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.

rs3824435 in PLGRKT gene and Alcoholic Intoxication, Chronic

PMID 28990359 2017 Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.

rs10392 in PPP1R16B gene and Alcoholic Intoxication, Chronic

PMID 28714907 2017 Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis.

rs2094081 in RHBDL2 gene and Alcoholic Intoxication, Chronic

PMID 29071344 2017 Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.

rs1451724 in RHOG gene and Alcoholic Intoxication, Chronic

PMID 23089632 2013 A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.

rs12392447 in RN7SL697P gene and Alcoholic Intoxication, Chronic

PMID 19581569 2009 Genome-wide association study of alcohol dependence.

rs139438618 in SEMA3A gene and Alcoholic Intoxication, Chronic

PMID 29071344 2017 Under the linear regression model, rs139438618 at the semaphorin 3A (SEMA3A [OMIM 603961]) locus was significantly associated with AD and MD comorbidity in African American participants in the Yale-Penn 1 sample (β = 0.89; 95% CI, 0.57-1.20; P = 2.76 × 10-8).

rs4478858 in SERINC2 gene and Alcoholic Intoxication, Chronic

PMID 23455491 2013 NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent.

rs11922615 in SETD5 gene and Alcoholic Intoxication, Chronic

PMID 22096494 2011 A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study.

rs13107325 in SLC39A8 gene and Alcoholic Intoxication, Chronic

PMID 30940813 2019 Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.

rs12489456 in SLC6A6 gene and Alcoholic Intoxication, Chronic

PMID 21956439 2012 Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.

rs79246196 in STAG3 gene and Alcoholic Intoxication, Chronic

PMID 29071344 2017 Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.

rs11583322 in STK40 gene and Alcoholic Intoxication, Chronic

PMID 23691058 2013 Dosage transmission disequilibrium test (dTDT) for linkage and association detection.

rs1000579 in STX18-AS1 gene and Alcoholic Intoxication, Chronic

PMID 22004471 2012 Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.

PMID 28714907 2017 Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis.

rs1869324 in THSD7B gene and Alcoholic Intoxication, Chronic

PMID 21703634 2011 A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.

rs11623335 in TMEM260 gene and Alcoholic Intoxication, Chronic

PMID 21956439 2012 Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.

rs3736802 in TRPC4AP gene and Alcoholic Intoxication, Chronic

PMID 23089632 2013 A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.

rs57083693 in UTP20 gene and Alcoholic Intoxication, Chronic

PMID 24962325 2014 Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.