Gene: LOC100507053

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 4

Location in Chromosome : 4q23

Description of this Gene: uncharacterized LOC100507053

Type of Gene: ncRNA

Gene: ADH4

Alternate names for this Gene: ADH-2|HEL-S-4

Gene Summary: This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.

Gene is located in Chromosome: 4

Location in Chromosome : 4q23

Description of this Gene: alcohol dehydrogenase 4 (class II), pi polypeptide

Type of Gene: protein-coding

rs17028615 in LOC100507053;ADH4 gene and Alcohol-Induced Disorders PMID 24166409 2014 Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.

rs17028615 in LOC100507053;ADH4 gene and Alcohol-Related Disorders PMID 24166409 2014 Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.

rs17028615 in LOC100507053;ADH4 gene and Alcoholic Intoxication, Chronic PMID 24166409 2014 Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.

rs1800759 in LOC100507053;ADH4 gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs13110764 in LOC100507053;ADH4 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

rs17028615 in LOC100507053;ADH4 gene and Serum albumin measurement PMID 24625756 2014 Genetic determinants influencing human serum metabolome among African Americans.